This study investigates the effects of learning orientation and global mindset on virtual team member’s willingness to cooperate. It also explores the mediating role of self-efficacy in these relationships. To test the hypothesized relationships, the study used a sample of 224 employees from five global companies in South Korea. The results show that while global mindset is directly and positively related to virtual team members’ willingness to cooperate, learning orientation is not. Self-efficacy serves as a mediator in these relationships. The study concludes with a discussion of the theoretical contributions and managerial implications for improving virtual team members’ cooperative behavior.