For a large class of neutral population models the asymptotics of the ancestral structure of a sample of n individuals (or genes) is studied, if the total population size becomes large. Under certain conditions and under a well-known time-scaling, which can be expressed in terms of the coalescence probabilities, weak convergence in DE([0,∞)) to the coalescent holds. Further the convergence behaviour of the jump chain of the ancestral process is studied. The results are used to approximate probabilities which are of certain interest in applications, for example hitting probabilities.

A variety of convergence results for genealogical and line-of-descendent processes are known for exchangeable neutral population genetics models. A general convergence-to-the-coalescent theorem is presented, which works not only for a larger class of exchangeable models but also for a large class of non-exchangeable population models. The coalescence probability, i.e. the probability that two genes, chosen randomly without replacement, have a common ancestor one generation backwards in time, is the central quantity to analyse the ancestral structure.

A simple convergence theorem for sequences of Markov chains is presented in order to derive new ‘convergence-to-the-coalescent’ results for diploid neutral population models.

For the so-called diploid Wright-Fisher model with selfing probability s and mutation rate θ, it is shown that the ancestral structure of n sampled genes can be treated in the framework of an n-coalescent with mutation rate ̃θ := θ(1-s/2), if the population size N is large and if the time is measured in units of (2-s)N generations.

‘Convergence-to-the-coalescent’ theorems for two-sex neutral population models are presented. For the two-sex Wright-Fisher model the ancestry of n sampled genes behaves like the usual n-coalescent, if the population size N is large and if the time is measured in units of 4N generations. Generalisations to a larger class of two-sex models are discussed.