Observations of CO can provide constraints on the density and temperature of the dense star-forming gas in galaxies, while observations of [CI] trace photon-dominated regions and provide information on the amount of atomic carbon in molecular clouds. In this paper, I review CO and [CI] observations of nearby galaxies, with an emphasis on galaxies for which high-resolution observations of multiple transitions and isotopologues are available. I also briefly discuss upper limits on water emission from nearby starburst galaxies and on O2 emission in the SMC obtained with the Odin satellite.