War, captives, and human sacrifice were parts of Late Postclassic (AD 1250–1524) Maya culture in highland Guatemala. Las Casas (1958:152) wrote that the supreme lord “put the heads of the sacrificed on some poles on a certain altar dedicated only to this, where they had these for some time, after which they buried them.” These cultural aspects show up in human remains excavated at Iximche’, the Kaqchikel Maya capital. Here, we integrate previously published and unpublished results of stable isotope analyses and explore their implications for diets and the geographic origins of individuals who were buried at the site on the eve of the Spanish conquest. Data from Iximche’ are compared with available results from other ancient Maya sites.