Smooth barley is an annual weed species that is infesting crops and pastures in South Australia. Complicating control options is the presence of herbicide-resistant biotypes. A field trial was conducted to identify alternative herbicides for the management of acetyl coenzyme A carboxylase (ACCase)-inhibiting herbicide-resistant smooth barley in field pea. Preplant (PP) soil applications of pyroxasulfone; prosulfocarb plus S-metolachlor; dimethenamid-P; propyzamide; trifluralin alone or with triallate or with diuron; or imazamox applied POST were evaluated for their effectiveness and crop safety. Propyzamide, pyroxasulfone, or imazamox applied POST provided a high level of smooth barley control, did not cause any crop injury, and increased field pea grain or forage yield compared with the nontreated. Furthermore, propyzamide or pyroxasulfone reduced panicle density and seed production in smooth barley, whereas the effectiveness of POST imazamox varied over the two seasons. Dimethenamid-P reduced the impact of smooth barley on field pea yield, but cause stunting, and was less effective than propyzamide, pyroxasulfone, and imazamox in reducing smooth barley seed production. Negative relationship between field pea yield and smooth barley panicle density indicated that smooth barley is highly competitive in field pea crops and can cause large yield losses. The results of this investigation suggest that propyzamide or pyroxasulfone applied PP and imazamox applied POST could be used effectively in the field for the management of ACCase-inhibiting herbicide-resistant smooth barley in South Australia.