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discordant anomaly

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Chapter 11 - Management of Discordant Fetal Anomaly
- By Rajit Narayan, Jon Hyett
Edited by Leanne Bricker, Julian N. Robinson, Baskaran Thilaganathan, St George's Hospital Medical School, University of London
Book:

Management of Multiple Pregnancies

Published online:

11 October 2022

Print publication:

27 October 2022, pp 112-122
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Summary

Twin pregnancies may be complicated in a number of ways, including through presentation with fetal abnormality. Pregnancies that are discordant for fetal anomaly may be impacted by a range of complications which are dependent on zygosity, chorionicity and the specific anomaly concerned. Discordance is defined as “occurrence of a trait or disease in only one member of a matched pair of subjects, especially twins”. In this chapter, we have reviewed the prevalence of various fetal anomalies in twin pregnancies, identified means for detecting these prenatally and reviewed a range of approaches to managing these anomalies considering the impact on the affected fetus, the co-twin and the wider family.