Let S be a countable set and let Q = (qij, i, j ∈ S) be a conservative q-matrix over S with a single instantaneous state b. Suppose that we are given a real number μ ≥ 0 and a strictly positive probability measure m = (mj, j ∈ S) such that ∑i∈Smiqij = −μmj, j ≠ b. We prove that there exists a Q-process P(t) = (pij(t), i, j ∈ S) for which m is a μ-invariant measure, that is ∑i∈Smipij(t) = e−μtmj, j∈S. We illustrate our results with reference to the Kolmogorov ‘K1’ chain and a birth-death process with catastrophes and instantaneous resurrection.