Conformal image registration has always been an area of interest among modern researchers, particularly in the field of medical imaging. The idea of image registration is not new. In fact, it was coined nearly 100 years ago by the pioneer D’Arcy Wentworth Thompson, who conjectured the idea of image registration among the biological forms. According to him, several images of different species are related by a conformal transformations. Thompson’s examples motivated us to explore his claim using image registration. In this paper, we present a conformal image registration (for the two-dimensional grey scaled images) along with a penalty term. This penalty term, which is based on the Cauchy–Riemann equations, aims to enforce the conformality.