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1 results

  • Chapter 17 - Head and Neck Cancer

  • Edited by Laurie J. Mckenzie, University of Texas MD Anderson Cancer Center, Houston, Denise R. Nebgen, University of Texas MD Anderson Cancer Center, Houston
  • Book:
    Caring for the Female Cancer Patient
    Published online:
    23 October 2024
    Print publication:
    17 October 2024, pp 284-303

  • Summary

    Human papillomavirus (HPV) is a leading cause of cancer and cancer-related death in women, overwhelmingly attributed to rates of cervical cancer in low and middle-income countries. However, in the U.S., HPV-related oropharyngeal cancer (OPC) has surpassed cervical cancer as the most common HPV-related cancer, although it is much more common (5-fold) in men than women. Similar to other head and neck cancer, HPV-related OPCs typically require complex multidisciplinary treatments often with major lifelong sequelae. However, HPV-related OPCs have much better cancer cure rates and lower second primary malignancy rates than tobacco-related head and neck cancer. Unique patterns of second primary malignancies, related to HPV exposures, are often a concern for female patients. This chapter will focus on HPV-related OPC, its associations with other malignancies in women, and prevention / screening recommendations and potentials for women with HPV-related OPC.