The Submillimeter Wave Astronomy Satellite (SWAS) has recently completed 5.5 years of successful operation. Among the legacies of the mission has been a greater understanding of the abundance and spatial distribution of H2O and O2 within molecular clouds. We summarize SWAS results and discuss how the measured low abundance of water vapor and non-detections of molecular oxygen are suggestive of a general lack of atomic oxygen in the dense centers of molecular clouds. We also present a new more comprehensive model for the oxygen chemistry in the interstellar medium.