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adjuvant radiation therapy

Journal of Radiotherapy in Practice (1)

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Liposarcoma of the left hemithorax and implications of MDM2
Michael Stolten, Deepak Sahasrabudhe, Louis Constine
Journal:

Journal of Radiotherapy in Practice / Volume 18 / Issue 4 / December 2019

Published online by Cambridge University Press:

28 May 2019, pp. 397-399
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Background:
Use of molecular information to guide clinical management of thoracic liposarcoma following resection.
Case presentation:
We present a case of a large liposarcoma of the left hemithorax. Initial biopsy consistent with lipoma however following resection pathology showed well-differentiated liposarcoma. Clinical data and molecular information including MDM2 from the tumour were employed in decision making regarding subsequent adjuvant radiation therapy versus close observation.
Conclusion:
Improved molecular characterisation has increased the precision of histological diagnoses and prediction of outcomes for many cancers. These may continue to help guide and strengthen clinical decision making and recommendations as they pertain to adjuvant therapy versus observation in the case of this patient.