We report the first non-indigenous dottyback Pseudochromis persicus record in the Mediterranean Sea. A single individual was documented several times at the same location on October 2024 in Bat Galim reef, a shallow rocky shelf of Rosh Carmel underwater ridge on the northern coast of Israel. This record represents the first sighting of Pseudochromidae, a family native to the Indo-Pacific Ocean, in the Mediterranean Sea. It is also the first record of P. persicus beyond its native range in the Persian Gulf and the Arabian Sea.