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Chapter 53 - Thrombotic Thrombocytopenic Purpura in Pregnancy
from Section 9 - Hematologic Conditions in Pregnancy
- By Paula D. James, Laura M. Gaudet
Edited by Amira El-Messidi, McGill University, Montréal, Alan D. Cameron, University of Glasgow
Book:

OSCEs in Obstetrics and Maternal-Fetal Medicine

Published online:

23 February 2023

Print publication:

16 February 2023, pp 680-689
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Summary

During your call duty, a healthy 32-year-old primigravida at 22+3 weeks’ gestation, confirmed by first-trimester sonography, presents to the obstetrics emergency assessment unit of your hospital center with new-onset, asymptomatic port-wine-colored urine with chills and an oral temperature of 39.1°C at home; she also notes a two-day history of headache, now accompanied by visual changes. Your obstetric trainee informs you that clinical history is not suggestive of an infectious etiology, although comprehensive investigations are pending. She has no obstetric complaints, and fetal viability was ascertained upon presentation. Routine prenatal laboratory investigations, aneuploidy screening, and fetal morphology survey were unremarkable. The laboratory urgently notifies you that the platelet concentration is 12 × 109/L, confirmed on manual count; other requested laboratory tests are in progress.