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3 results

  • Stage is a prognostic factor for surgically treated patients with early-stage lip cancer for whom a ‘wait and see’ policy in terms of neck status has been implemented

  • G Eskiizmir, E Ozgur, G Karaca, P Temiz, N Hacioglu Yanar, B Cengiz Ozyurt
  • Journal:
    The Journal of Laryngology & Otology / Volume 131 / Issue 10 / October 2017
    Published online by Cambridge University Press:
    15 August 2017, pp. 889-894
    Print publication:
    October 2017
  • Objectives:

    To determine the locoregional control and survival rates (in terms of risk factors) of patients who underwent surgical resection of early-stage lip cancer and for whom a ‘wait and see’ policy in terms of neck status had been implemented.

    Methods:

    The sociodemographic data, tumour stage, tumour characteristics and histopathological features of 41 patients with early-stage lip cancer were evaluated. Factors predictive of survival and locoregional recurrence were analysed. The five-year overall survival and disease-free survival rates were determined, and the prognostic risk factors were compared.

    Results:

    The mean follow-up period was 60.5 months (range, 4–92 months). Age, sex, tumour stage, tumour thickness and volume, and perineural involvement were not predictive of locoregional recurrence or survival. Pathological tumour stage (T1vs T2) was a prognostic factor for both five-year overall survival (87.3 vs 65.6 per cent, p = 0.042) and disease-free survival (88.6 vs 65.6 per cent, p = 0.037).

    Conclusion:

    Tumour stage was clearly a major factor affecting the prognosis of surgically treated patients with early-stage lip cancer for whom a ‘wait and see’ policy in terms of neck status had been implemented.

  • Early stage squamous cell carcinoma of the lower lip: predictive factors for recurrence

  • Y Ozkul, M Songu, A Imre, E Tunc, Z Ozkul, S Arslanoglu, E Pinar, K Onal
  • Journal:
    The Journal of Laryngology & Otology / Volume 130 / Issue 4 / April 2016
    Published online by Cambridge University Press:
    10 February 2016, pp. 369-372
    Print publication:
    April 2016
  • Objective:

    This study aimed to evaluate the effect of tumour thickness on other clinicopathological parameters in early stage lower lip squamous cell carcinoma.

    Methods:

    Forty-six consecutive patients with lower lip squamous cell carcinoma were included in the study. Demographic, clinical and pathological data were retrospectively collected.

    Results:

    The mean follow-up period for all patients was 32.0 ± 18.9 months. Forty-four tumours were staged as T1 and two were T2. Twelve patients underwent neck dissection. Two patients presented with neck metastasis in the follow-up period. Four patients (8.7 per cent) had local recurrence. Correlation analysis revealed a significant relationship between microscopic tumour thickness and local tumour recurrence (r = 0.328, p = 0.045).

    Conclusion:

    Surgical margin control is important to prevent local recurrence, especially in thicker tumours. In addition, neck metastasis is rare in early stage lower lip squamous cell carcinoma. A ‘wait and see’ policy might be preferred in early stage T1 lower lip squamous cell carcinoma cases.

  • True mailgnant mixed tumour of a minor salivary gland

  • S. C. Toynton, M. J. Wilkins, H. T. Cook, N. D. S. Stafford
  • Journal:
    The Journal of Laryngology & Otology / Volume 108 / Issue 1 / January 1994
    Published online by Cambridge University Press:
    29 June 2007, pp. 76-79
    Print publication:
    January 1994

  • True malignant mixed tumours (carcinosarcomas) of salivary gland origin are rare and not widely recognized lesions. These tumours account for approximately 0.2 per cent of all malignancies of the major salivary glands (Stephen et al., 1986). They usually occur in pre-existing pleomorphic ademonas of major salivary glands and have an aggressive and often rapidly fatal progression.

    We report a case of carcinosarcoma in a minor salivary gland of the upper lip. Its management and the use of immunocy-tochemical stains to demonstrate the separate epithelial and connective issue components are discussed.