One century after its initial excavation, this article presents the first absolute chronology for the settlement of Karanis in Egypt. Radiocarbon dates from crops retrieved from settlement structures suggest that the site was inhabited beyond the middle of the fifth century AD, the time at which it was previously believed to have been abandoned. These dates add to the complex picture of population fluctuations and the remodelling and reuse of structures at Karanis. Two dates reach into the middle of the seventh century, placing the abandonment of the site in a period of political and environmental transition that changed the physical and social landscape of the Fayum region and beyond.