A specimen of bigscale jawfish, Opistognathus macrolepis (Perciformes: Opistognathidae) was collected from the travelling water screen of Madras Atomic Power Station pump house, located at Kalpakkam, south-east coast of India. Opistognathus macrolepis was previously known only from central west Pacific, from the Gulfs of Thailand and Carpentaria, Australia. The present study reports the first record of its occurrence in the Indian Ocean from the east coast of India and constitutes a new addition to the Indian coastal ichthyofauna.