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1 results

  • Malignant glomus tumour of larynx: first case report and literature review

  • N Aslam, Z-U-S Qazi, A H Ahmad, R U Khan
  • Journal:
    The Journal of Laryngology & Otology / Volume 126 / Issue 7 / July 2012
    Published online by Cambridge University Press:
    14 May 2012, pp. 743-746
    Print publication:
    July 2012
  • Objective:

    We describe the first reported case of a malignant glomus tumour of the larynx.

    Method:

    Case report and review of the world literature concerning malignant glomus tumours.

    Results:

    A 37-year-old man presented with progressive hoarseness and dyspnoea. A smooth, right-sided laryngeal mass was found on flexible nasolaryngoscopy. Initial biopsy of this lesion was reported as a true ‘glomus tumour’, which is a benign lesion. Wide local excision was performed. The final histology of this specimen showed it to be a ‘malignant glomus tumour’. Immunohistochemistry was positive for smooth muscle actin, collagen type IV, vimentin and cluster of differentiation 34 glycoprotein. Total laryngectomy was then performed as a definitive curative procedure.

    Conclusion:

    Glomus tumour is rarely found in visceral locations. This tumour and its malignant counterpart are rare differential diagnoses of laryngeal masses.