We present X-ray properties of NGC 300 point sources, extracted from 66 ksec of XMM-Newton data taken in 2000 December and 2001 January. A total of 163 sources was detected in the energy range of 0.3–6 keV. We report on the global properties of the sources detected inside the $D_{25}$ optical disk, such as the hardness ratio and X-ray fluxes, and spectral fitting of the brightest sources. We also present some properties of their optical counterparts found in B, V, and R images from the 2.2 m MPG/ESO telescope. Furthermore, we cross-correlate the X-ray sources with SIMBAD, the USNO-A2.0 catalog, and radio catalogues.