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1 results

  • Three case reports of emergent dyskinesia with clozapine

  • Rafael Gafoor, Justin Brophy
  • Journal:
    European Psychiatry / Volume 18 / Issue 5 / August 2003
    Published online by Cambridge University Press:
    16 April 2020, pp. 260-261

  • Clozapine is indicated for the treatment of patients intolerant of conventional antipsychotic agents. It is often used to treat those patients who have developed movement disorders while on conventional antipsychotics. We report three cases of dyskinesia associated with clozapine induction. We suggest a mechanism that might explain an underlying dopaminergic hypersensitivity during this transitional period. Further, we identify groups that might be at high risk of developing dyskinesia and suggest strategies to reduce risk especially in these groups.