Kinetic collisionless expansion of a spherical cluster composed of light and heavy cold ions and hot electrons is studied for arbitrary electron temperature. A wide set of regimes of plasma expansion, from nearly quasi-neutral to Coulomb explosion, is described from a unified description. The time evolution of the velocity, density, and energy spectra for accelerated ions is studied. The study demonstrates that an optimum light ion concentration from few percent to few tens percent, depending on the electron temperature, leads to a quasi-monoenergetic spectra with numbers as high as 70–80% of the total number of light ions.