Background
Prevalence of child and adolescent mental illness has increased over time. Repeated UK surveys show a six fold increase in reported prevalence of ‘long standing’ MH conditions in England (Pitchforth et al. Reference Pitchforth, Fahy, Ford, Wolpert, Viner and Hargreaves2019). Similar increased rates have been reported in the USA with the 12-month prevalence of depression increasing from 8.7% to 11.3% in adolescents between 2005 and 2014, reaching 12.9% by 2016 (Lu, Reference Lu2019). Whether such increases in prevalence apply to Ireland is more difficult to establish, as data collection on Child and Adolescent Medical Health Services (CAMHS) activity is fragmented. By 2018, estimates were that 1.6% of under 18-year-olds were attending CAMHS at any given time, increasing from 1.5% in 2013 (Ryan, Reference Ryan2020). Recent issues relating to the Covid-19 pandemic were predicted to further increase demand, and empirical data has confirmed this (McNicholas et al. Reference McNicholas, Kelleher, Hedderman, Lynch, Healy, Thornton, Barry, Kelly, McDonald and Holmes2021). High levels of staff burnout were present pre-pandemic, some attributable to a sense of unrealistic public expectations of what can be delivered within the limited resources (Doody et al. Reference Doody, O’Connor and McNicholas2021).
In this context of CAMHS under unprecedented pressure, robust epidemiological data on mental illness among youth in Ireland is needed to understand need and allow appropriate service planning and resource allocation.
Aims
This systematic review aims to present robust data on rates of mental health disorders in children and adolescents in Republic of Ireland.
Methods
A systematic search was conducted using Embase, PubMed, PsycInfo and CINAHL, to retrieve literature on prevalence of mental illness in children and adolescents aged under 18 in the Republic of Ireland (ROI). Search terminology is presented in Table 1. Past issues of Irish peer-reviewed publications (Irish Medical Journal, Irish Journal of Psychological Medicine, and Irish Journal of Medical Science) were hand-checked from January 1980 to July 2021 to identify any additional relevant studies. References of selected papers were reviewed for further qualifying studies and, given the prominence of the Growing Up in Ireland (GUI) study, a further search was conducted for relevant reports published by the GUI Research Team. The CoCoPop Framework (Condition, Context, Population) was used to structure the search (Munn et al. Reference Munn, Moola, Lisy, Riitano and Tufanaru2015). The Joanna Briggs Institute criteria were also independently applied to evaluate quality of studies and risk of bias (Munn et al. Reference Munn, Moola, Riitano and Lisy2014). Titles, abstracts and full text articles were screened against eligibility criteria by at least two independent reviewers and any disagreements mediated through a third team member. Only studies with empirical data for under-18s, conducted using data on ROI and using psychometric questionnaires or interviews, were included. Duplicates were excluded using EndNote. Reasons for exclusion were documented under the following headings: 1 = Population not ROI or cannot separate; 2 = Population not under 18 or cannot separate; 3 = population is a specific vulnerable group, clinical setting but not general population; 4 = no quantitative data for ROI; 5 = data not related to mental illness or no validated psychometric instrument used. The systematic review was prospectively registered in PROSPERO (the International Prospective Register of Systematic Reviews) by the first author (SL). A PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart displays the articles examined at each stage, detailing the number of papers included and excluded, and reasons for exclusions. Data extraction included study author(s), publication year, study population, main outcome measure used, sample size, prevalence/incidence, study design, year data collected. A narrative approach was used to synthesize the findings and prevalence data was grouped according to main cohorts examined (e.g. Growing up in Ireland, My World Survey) or by diagnostic/psychological groups (i.e. eating disorder, psychosis etc.).
Table 1. Search Terminology.
Although self-harm or suicidal ideation do not always imply a psychiatric illness, or a need for psychiatric treatment, given their frequent co-occurrence in mental illness and their link with subsequent suicide, the intention of this review was to seek estimates of prevalence rates and include them in the report. However, on further study scrutiny, there were significant differences in terminology, definitions and timeframes used, making it very difficult to combine. These findings will therefore be the subject of a separate paper.
Results
A total of 38 studies were identified (Table 2) as meeting study criteria, with some papers reporting on the same study population. As such, data is presented in groups according to the main data source, i.e. (i) Growing up in Ireland, (ii) My World Survey (iii) Challenging Times study and (iv) a final group reporting on various studies conducted among community samples. Details of quality assessment of all included papers is presented in the supplementary online table.
Table 2. Included studies (N = 38)
GUI: Growing Up in Ireland; MWS: My World Survey; EPICA: Eating Problems in Irish Children and Adolescents; HBSC: Health behaviour in School-aged Children; SEYLE: Saving and Empowering Young Lives in Europe; CASE: Child and adolescent Self-harm in Europe study.
Growing Up in Ireland study
The Growing Up in Ireland (GUI) study, funded by the Department of Children and Youth Affairs (DCYA) and Atlantic Philanthropies, is probably the most important study offering insight into the MH and psycho-social functioning of youth in Ireland. This prospective longitudinal study recruited an infant (11,100 infants) and child cohort (8,570 9-year-olds), which were followed up at 3 time points over 9 years. An online survey, completed by 3,301 12-year-olds from the infant cohort, reported on emotional wellbeing during Covid-19 (Murray et al. Reference Murray, McNamara, O’Mahony, Smyth and Watson2021). The Strength and Difficulties questionnaire (SDQ) (Goodman et al. Reference Goodman, Ford, Simmons, Gatward and Meltzer2000) was the main outcome measure, along with some study-specific questions enquiring about MH or treatment. Methodological strengths include longitudinal follow-up, large sample size drawn from a representative national sample and study sample weights which ensure representativeness to general population, high original response rate (57% child cohort and 81% infant cohort), low attrition rate, multi-modal interviews with validated youth, and parents’ questionnaires at each wave, supported by in-person interviews and (at age 9) teachers’ questionnaires. The statistical weighting system used by GUI (GROSS) uses a standard iterative adjustment procedure to compensate for unequal selection, non-response, or differences in sample selection with reference to population census data on socio-economic status, social class and family structure. Recognized limitations of GUI include using a categorical rather than dimensional approach to define psychopathology, lack of validated clinical information, lack of impairment criteria and reliance in general on primary carer report rather than multi-informant in waves 1 & 2. GUI received ethical approval from the Irish Health Research Board’s Research Ethics Committee. Details of methodology and findings are accessible at https://www.growingup.ie/ including a list of 165 associated peer-reviewed publications. For this review, all titles and abstracts were scrutinized to help identify material related to MH disorders.
A number of reports produced by the GUI team discuss social and emotional outcomes. Of the child cohort at age 9 (n = 8570), 7% had a problematic or abnormal SDQ score (Williams et al. Reference Williams, Greene, Doyle, Harris, Layte, McCoy, McCrory, Murray, Nixon and O'dowd2009). Parents also reported that 11% of 9-year-olds had either a chronic illness or disability (boys 13%, girls 10%), of whom 19% reported it as ‘a mental and behavioural problem’ (boys 24%, girls 12%) (Williams et al. Reference Williams, Greene, Doyle, Harris, Layte, McCoy, McCrory, Murray, Nixon and O'dowd2009). At age 13 (n = 7423), Nixon (Reference Nixon2021) states 6% (n = 444) of adolescents were in the abnormal SDQ range, while Watson et al. (Reference Watson, Maître, Whelan and Williams2014) using the same cohort (n = 7423) describes 6.5% (n = 481) in the abnormal range. Of this cohort, 16% scored above the cut-off on the Short Mood and Feelings Questionnaire (SMF) (Angold et al. Reference Angold, Costello, Messer and Pickles1995) indicating risk of depression, with significantly more girls (18%) than boys (14%) categorised in the ‘at risk’ group (Nixon, Reference Nixon2021). When this child cohort reached age 17/18, in a sample of 6,216 youth, 20% scored above the SMF cut-off, with the rate continuing to be substantially higher for girls (24%) than boys (16%) (McNamara et al. Reference McNamara, Murphy, Murray, Smyth and Watson2020). 10% of the sample self-reported they have been ‘diagnosed’ with depression or anxiety and more girls than boys reporting hurting themselves on purpose (17% overall: girls 23%, boys 12%) (Growing Up in Ireland, 2020).
In addition to information from the GUI reports, the search strategy identified a further 7 GUI-related publications, replicating reported findings described above (Reulbach et al. Reference Reulbach, O'Dowd, McCrory and Layte2010; Cotter et al. Reference Cotter, Healy, Cathain, Williams, Clarke and Cannon2019), with some papers providing additional analysis (Gallagher et al. Reference Gallagher, Galvin, Robinson, Murphy, Conway and Perry2020; Healy et al. Reference Healy, Coughlan, Williams, Clarke, Kelleher and Cannon2019a; O’Connor et al. Reference O’Connor, Reulbach, Gavin and McNicholas2018). O’Connor and colleagues reported a slightly higher rate of general psychopathology (Total SDQ 17–40, or ‘abnormal’) as 7.3% of 9-year-olds and 6.5% of 13-year-olds (n = 7,488: respondents to both waves). Examining the overall continuity rate (i.e. the proportion who retained the same classification in both waves), 2–3% of youth were considered to have ‘chronic’ MH problems. Healy et al. Reference Healy, Coughlan, Williams, Clarke, Kelleher and Cannon(2019a) measured psychotic experiences (PEs) at age 13 (n = 7,423) using six questions from the 7-question Adolescent Psychotic Symptoms Screener (APSS) (Kelleher et al. Reference Kelleher, Harley, Murtagh and Cannon2011), included in the GUI dataset, of whom 13% (n = 934) had at least one psychotic experience. At age 17/18 (n = 6,216), 9% were in the at risk category based on the APSS score (McNamara et al. Reference McNamara, Murphy, Murray, Smyth and Watson2020). Gallagher and colleagues reported that 17.4% (n = 1,304) of 13-year-olds had at least one developmental disability, more prevalent in males (19.8%) than females (15%), based on the response by the primary care giver as to whether their child had received any developmental disability diagnosis from the following: physical disability (hearing or vision), specific or general learning disability, autism spectrum disorder or ‘an emotional and behavioural disorder’ (EBD). Relevant to this paper, 1.5% (n = 118) were reported as having EBD and 1.3% (n = 97) ASD (Gallagher et al. Reference Gallagher, Galvin, Robinson, Murphy, Conway and Perry2020).
Whilst psychopathology is more prevalent in young boys, psychological wellbeing improves in boys, so that by age 17 there are more males in the normal range than girls (McNamara et al. Reference McNamara, Murphy, Murray, Smyth and Watson2020). Girls improve from ages 9 to 13, but by age 17 more girls have abnormal scores than boys, a pattern which often continues into adulthood (McNamara et al. Reference McNamara, Murphy, Murray, Smyth and Watson2020) (Table 3). At age 17, 10% stated they had been diagnosed with depression or anxiety by a doctor, and 4% of the total sample self-reported current treatment from a MH professional (Growing Up in Ireland, 2020).
Table 3. GUI and prevalence of psychopathology
SDQ: Strengths and difficulties Questionnaire; ADHD: attention deficit hyperactivity disorder; SMFQ: Short Mood & Feelings Questionnaire; APSS: adolescent Psychotic Screening Scale; ASD: Autism Spectrum Disorder.
The GUI datasets include weights to adjust the sample to known population parameters (socio-economic status, social class and family structure) and, while all papers use these weights in their detailed statistical analysis, not all apply weights to initial descriptive tables (Burke, Reference Burke2020; McDonnell, Reference McDonnell2016) and therefore report problematic SDQ prevalence rates below those of the GUI reports.
A brief survey was conducted during Covid-19, with 3,301 12-year-olds from Cohort ’08 (Murray et al. Reference Murray, McNamara, O’Mahony, Smyth and Watson2021). When responding to a five-item questionnaire (MHI5) (Berwick et al. Reference Berwick, Murphy, Goldman, Ware, Barsky and Weinstein1991), 22% of 12-year-olds reported ‘low mood’ (Murray et al. Reference Murray, McNamara, O’Mahony, Smyth and Watson2021).
My World Survey
A second seminal and methodologically rigorous representative cross-sectional study is the My World Survey (MWS), which collected data on over 14,000 young people aged 12–25 (Dooley & Fitzgerald, Reference Dooley and Fitzgerald2012). Data from second level students aged 12–19 (n = 6,085) are pertinent to this systematic review, and described as the Adolescent Sample – MWS-SL or Second Level (MWS1-SL, https://jigsaw.ie/wp-content/uploads/2020/07/MWS1_Full_Report_PDF.pdf).
72 post-primary schools were recruited from which 6,085 students completed the survey. The study used a variety of methods to determine positive and negative mental health domains, including some validated MH questionnaires. The Depression, Anxiety and Stress Scale (DASS-11) was used to screen for rates of depression and anxiety, enquiring about negative emotions over the previous week (Lovibond & Lovibond, Reference Lovibond and Lovibond1995). Different cut-offs identify youth as displaying normal, mild, moderate, severe and extremely severe mood related symptoms and the authors provide the percentage of the sample scoring above the various cut off. However, given the time duration of 1 week, this does not easily allow an estimate of rate of depression or anxiety, but offers a useful metric to identify risk, especially if those scoring in the most extreme category, ‘very severe’, are considered.
Over one-third of the sample of young people were outside the normal range for both depression (35% overall, 4% very severe) and anxiety (34.5% overall, 7% very severe), more common among females, and 4% identified as having very severe psychological difficulties, while 2% had very severe stress (Dooley & Fitzgerald, Reference Dooley and Fitzgerald2012). A study-specific question asked about receiving specialist mental health therapeutic support; 11% responded affirmatively, with no gender effect. This increased with age; 8% of respondents in first year received support, increasing to 17% of sixth year students. 60% reported such contact was ‘helpful’. When asked about serious mental health problems in the prior year that needed formal support, 9% felt they had such problems but only 6% had sought formal support. Those self-identifying a need for specialist mental health support had higher rates of depression or anxiety as measured by standardized questionnaires, suggesting validity of measures.
A second survey, was conducted in 2019 with 10,459 adolescents in secondary school, aged 12–19, referred to as MWS-2-Second Level (MWS-2-SL). This showed a notable increase in rates scoring in the abnormal range for anxiety (49%) and depression (40%). In both surveys, rates were higher in females (Dooley et al. Reference Dooley, O’Connor, Fitzgerald and O’Reilly2019).
The search strategy identified two additional relevant MWS publications. Dooley et al. Reference Dooley, Fitzgerald and Giollabhui(2015) reported on risk and protective factors; 8% of the sample were reported to have severe or very severe depressive symptoms and 11.3% anxiety symptoms in the prior week. Dolphin et al. (Reference Dolphin, Dooley and Fitzgerald2015) examined prevalence and correlates of psychotic-like experiences (PLE), based on questions from the Adolescent Psychotic-Like Symptom Screener (APSS) (Kelleher et al. Reference Kelleher, Harley, Murtagh and Cannon2011). 13.7% reported auditory hallucinations, 10.4% visual hallucinations and 13.1% paranoid thoughts.
The Challenging Times cohort
The search identified two publications which, according to the authors, reflect the first large scale two-stage study design (N = 723) conducted in Ireland specifically investigating rates of psychopathology among youth (aged 12-–15) (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004). Challenging Times used two commonly used screening questionnaires: SDQ (Goodman et al. Reference Goodman, Ford, Simmons, Gatward and Meltzer2000) and Children’s Depression Inventory (CDI) (Kovacs, Reference Kovacs1992) to identify those scoring in the clinical range. This was followed by an interview phase. 723 secondary school pupils completed the self-reported questionnaires allowing researchers to establish prevalence for general psychopathology. Suicidal intent was defined as an affirmative answer to the CDI item 9; ‘I want to kill myself’ and suicidal ideation by answering yes to ‘I think of killing myself but I would not do it’. Despite the large and representative sample from schools in a defined geographical area of Dublin, study limitations include low response rate, 51.2% (n = 723), and the gatekeeping nature of any school screening survey (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004). 17.8% (n = 129) scored above cut off levels on SDQ (>17) and 4.7% (n = 37) scored above cut-off on the CDI (>65) (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2006), indicating possible depressive disorder in the prior 2 weeks, 4.1% (n = 30) scored in clinical range on both CDI and SDQ. Screen-positive youth (n = 140) and a subsample of controls (n = 174), randomly selected, were invited for a semi-structured interview (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2006), of whom 101 (72%) and 94 (54%) respectively, agreed. The Schedule for Affective Disorders and Schizophrenia for School-aged Children, Present and Lifetime Version (K-SADS-PL) (Kaufman et al. Reference Kaufman, Birmaher, Brent, Rao, Flynn, Moreci, Williamson and Ryan1997) was used, giving a DSM IV current and past MH diagnosis of 15.6% and 19.9% respectively. Rates were 4.5% for affective disorder, 3.7% anxiety and 3.7% ADHD. Lower rates were found for conduct disorders (1.2%), oppositional defiant disorders (1.2%), with only one adolescent meeting criteria for tic and eating disorder. No youth met criteria for bipolar disorder. An additional paper (Mills et al. Reference Mills, Guerin, Lynch, Daly and Fitzpatrick2004) reported on the relationship between depression, suicidal thoughts and bullying, and on self-harm rates. This sample included both an ‘at risk group’ (n = 101) and controls (n = 108) and analysis presented based on bullying status. As the data analysis was not weighted to reflect attrition or sample bias, it was not possible to generate population prevalence.
Various community samples
Lawlor & James (Reference Lawlor and James2000) report on prevalence of psychological disorders in a community sample of 16-year-old school-going adolescents in northeastern Ireland (n = 779). Using the Youth Self-Report (YSR) scales (Achenbach, Reference Achenbach2001), 21.3% of the sample were classified in the clinical range for total problems, more girls (23%) than boys (19%). A 1 year follow up on a subset (n = 110 students) revealed similar rates (James et al. Reference James, Lawlor and Sofroniou2004). An additional study in the same region, with 992 adolescents aged between 13 and 17 was carried out (O’Farrell et al. Reference O’Farrell, Flanagan, Bedford, James and Howell2005). Using the Centre for Epidemiological Studies-Depression (CES-D) scale (Radloff, Reference Radloff1977), 206 (20.6%) of respondents had a depression score above cut-off, significantly more females (n = 152, 39%) than males (n = 54, 9%; p < 0.001).
Martyn et al. (Reference Martyn, Andrews and Byrne2014) studied prevalence of mental health difficulties in 237 adolescents 16–17 years of age in a rural western county. Assessments included the YSR, CDI, the Coping Inventory for Stressful Situations-Adolescent (Endler & Parker, Reference Endler and Parker1990) and The Family Assessment Device (Epstein et al. Reference Epstein, Baldwin and Bishop1983). 16.9% of participants reported clinically significant difficulties based on self-report questionnaire scores, with 5.5% scoring in the clinical range for depression.
Using the SDQ (Goodman et al. Reference Goodman, Ford, Simmons, Gatward and Meltzer2000) 14.6% of a sample of 1,131 youth aged 11–13 years recruited from primary schools from two geographical areas in Ireland (north Dublin city and county Kildare), scored in the borderline range (14-–16) and 6.9% abnormal (SDQ > 16) (Coughlan et al. Reference Coughlan, Tiedt, Clarke, Kelleher, Tabish, Molloy, Harley and Cannon2014). Subsequent interviews (n = 212) using the Kiddie-SADs revealed that 27.4% (n = 58) met diagnostic criteria for a ‘current’ Axis 1 disorder and 36.8% (n = 78) received a ‘lifetime’ diagnosis (Coughlan et al. Reference Coughlan, Tiedt, Clarke, Kelleher, Tabish, Molloy, Harley and Cannon2014). Removing phobias from the criteria, rates fell to 15.4% (current) and 31.2% (lifetime). A small cross-sectional sample (n = 93, age 15–18) reported on rates of psychological maladjustment and mental health service support among secondary school pupils in the south-east (Brennan & McGilloway, Reference Brennan and McGilloway2012). The Reynolds Adolescence Adjustment Screening Inventory (RAASI) (Reynolds, Reference Reynolds2001) classified 25% of participants as displaying psychological adjustment difficulties.
Eating problems were studied using a national sample of 3,031 second-level students aged between 12 and 19, from 48 schools across Ireland (McNicolas et al. Reference McNicholas, Dooley, Keogh, Lydon, Lennon, Ahern, Coyle, Whelan and Donoghue2010). 10.8% (n = 199) of females and 2.4% (n = 28) of males scored above clinically significant cut-off of 20 on the Eating Attitude Test (EAT-26) (Garner & Garfinkel, Reference Garner and Garfinkel1979; Garner et al. Reference Garner, Olmsted, Bohr and Garfinkel1982). 1.2% of females (0% males) were described as ‘at risk’ for anorexia nervosa, defined by a high EAT score low body mass index (BMI) and current dieting status (McNicolas et al. Reference McNicholas, Dooley, Keogh, Lydon, Lennon, Ahern, Coyle, Whelan and Donoghue2010). Murrin et al. (Reference Murrin, McNicholas, Keogh, Shiely, Corrigan, Gabhainn and Kelleher2007) used the 2002 Health Behaviour in School Aged Children (HBSC) data (n = 2,469) to examine BMI and perceived body size (Currie et al. Reference Currie, Roberts, Settertobulte, Morgan, Smith, Samdal, Barnekow Rasmussen and Organization2004) 3.5% (n = 86) were consider at risk of eating pathology, where they ‘thought they were too fat’, despite being in the underweight BMI category (BMI < 18.5 kg m2).
Kelleher et al. (Reference Kelleher, Murtagh, Molloy, Roddy, Clarke, Harley and Cannon2012) aimed to identify prevalence of prodromal risk syndromes among adolescents aged 11–13 attending schools in the east. Two hundred and twelve youth who scored above cut off on the SDQ had subsequent semi-structured interviews: Kiddie Schedule for Affective Disorders and Schizophrenia interview (K-SADS) (Kaufman et al. Reference Kaufman, Birmaher, Brent, Rao, Flynn, Moreci, Williamson and Ryan1997), Structured Interview for Prodromal Syndrome (SIPS) (Yung et al. Reference Yung, Phillips, Yuen, Francey, McFarlane, Hallgren and McGorry2003) and Comprehensive Assessment of At Risk Mental States (CAARMS) (Yung et al. Reference Yung, Phillips, Yuen and McGorry2006). A total of 22.6% (n = 53) reported psychotic symptoms, primarily auditory hallucinations, with 0.9% and 8% meting criteria for an ‘at risk’ syndrome, depending on whether a 30% reduction in impairment criteria was applied.
Sharkey & McNicholas (Reference Sharkey and McNicholas2012) studied the prevalence of selective mutism in all primary school children (n = 10,927) of a CAMHS catchment area in Dublin. This was a two-stage design: teacher questionnaires identified potential cases for psychiatric interview, following which a prevalence rate of 0.18% was established.
Discussion
Prevalence rates of mental health difficulties varied significantly, with overall current prevalence varying from 4.4% to 27.4%, likely reflecting heterogeneity of samples and methodologies. “Growing up in Ireland” and the “My World Study” are important large methodologically robust and representative studies that help paint a landscape of the extent of psychological difficulties under age 18. However, GUI SDQ data suggest lower than expected rates, while MWS report much higher rates.
GUI records between 4.8% and 7.3% of youth at various ages have mental health difficulties, with the highest rates at age 9 (7.3%). However, much higher rates (17.8%) were reported in the “Challenging Times” (CT) study (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004) using identical screening measure (SDQ) and cut offs. An inner-city sample in CT might contribute to higher psychopathology. However, in the most recent UK national survey (Vizard et al. Reference Vizard, Sadler, Ford, Newlove-Delgado, McManus, Marcheselli, Davis, Williams, Leach, Mandalia and Cart-Wright2020) of very similar design to GUI, 16% of youth aged 5–16 had ‘a probable mental health disorder’ rising to 20% in 16–20 year olds. Whilst this systematic review found one other study (Coughlan et al. Reference Coughlan, Tiedt, Clarke, Kelleher, Tabish, Molloy, Harley and Cannon2014) with rates similar to GUI (6.9%), the remaining Irish studies reported higher rates; 21% of 16 year olds (Lawlor & James, Reference Lawlor and James2000; James et al. Reference James, Lawlor and Sofroniou2004), 16.9% of 16–17 year-olds (Martyn et al. Reference Martyn, Andrews and Byrne2014) and 25% among 15–18 year-olds (Brennan & McGilloway, Reference Brennan and McGilloway2012). Whilst the later studies used different questionnaires, and were conducted earlier, this is unlikely to account for this difference, as psychopathology rates increased over time in other countries where serial data are available (Vizard et al. Reference Vizard, Sadler, Ford, Newlove-Delgado, McManus, Marcheselli, Davis, Williams, Leach, Mandalia and Cart-Wright2020). As such, this finding regarding lower rates of overall pathology as measured by SDQ in GUI is difficult to explain.
In terms of depression, 16% of GUI 13-year-olds rated above cut-off (Nixon, Reference Nixon2021), slightly lower than 20.8% reported by O’Farrell and colleagues (2005) but comparable to other international epidemiological studies (Costello et al. Reference Costello, Copeland and Angold2011). These rates were much lower than MWS. The first MWS reported 35% with raised scores for either depression or anxiety (Dooley & Fitzgerald, Reference Dooley and Fitzgerald2012), increasing to 40% and 49% respectively in their second study (Dooley et al. Reference Dooley, O’Connor, Fitzgerald and O’Reilly2019). Although more recent studies report a steady increase in adolescent depression (11.3% in 2014 to 12.9% in 2016), they do not reach rates reported in MWS (Lu, Reference Lu2019). Redefining the category in MWS to only the ‘most severe’ reduces rates of depressive (4%) and anxiety (7%) to be more aligned with both GUI and international data (Costello et al. Reference Costello, Copeland and Angold2011), highlighting the importance of the reader’s attention to methodological differences between studies.
By age 17/18, 10% of the GUI cohort reported having received a formal diagnosis of depression or anxiety from a doctor, psychologist or psychiatrist, with only 4% reporting current or past treatment. This is a similar rate to MWS where 11% of young people reported having seen a mental health professional, 9% self-identifying as having serious mental health issues and 6% having received treatment (Dooley & Fitzgerald, Reference Dooley and Fitzgerald2012). The gap in access to services in Ireland is much higher than reported in the UK, where in the most recent national mental health survey, 66.4% of youth with disorders had accessed services (Sadler et al. Reference Sadler, Vizard, Ford, Marchesell, Pearce, Mandalia, Davis, Brodie, Forbes and Goodman2018).
Neither GUI or MWS examined eating problems, and only one study was identified in the search, where 11% of females were reported to have eating concerns with 1.2% being at risk for anorexia nervosa (AN) (McNicolas et al. Reference McNicholas, Dooley, Keogh, Lydon, Lennon, Ahern, Coyle, Whelan and Donoghue2010). UK studies using an interview format found lower rates of 0.4% (Sadler et al. Reference Sadler, Vizard, Ford, Marchesell, Pearce, Mandalia, Davis, Brodie, Forbes and Goodman2018) and more recent studies suggest this has increased, especially under age 15, with lifetime prevalence rates of AN up to 4% among females and 0.3% among males (van Eeden et al. Reference Van Eeden, Van Hoeken and Hoek2021).
Some of the discrepancies between studies might be explained by methodological differences, including cohort selection, age group, different questionnaires and time frames examined. Studies fall short of identifying youth with more severe and enduring illness due to short timeframe of some questionnaires, lack of or inconsistent collateral school or multi-informant data, and lack of interview to determine persistence or degree of impairment or clinical psychopathology. Additionally, the use of different numbers in GUI-reported cohorts in various published papers, or different SDQ cut-offs, account for some slight differences in prevalence rates reported by different authors, even within the same cohort. Both GUI and MWS studies report a service gap between mental health need and access to treatment, highlighting the importance of ensuring services are both accessible and acceptable to youth.
Two-stage study design, including both screen-positive and a random sample of screen-negative youth, and using a well-validated research interview, should increase the validity of findings. However, despite this enhanced methodology, including the provision of weighted prevalence rates to generate estimates for the general population, prevalence rates in the studies identified by this review differed significantly.
Rates from semi-structured interviews also differed substantially. The “Challenging Times” study (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004) report rates of psychiatric disorder among 12–15 to be 15.6% (current) or 19.9% (lifetime). Rates for depressive disorder (4.5%), anxiety (3.7%) and ADHD (3.7%) were lower with no case found for schizophrenia or bipolar disorder (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004). Significantly higher rates (current 27.4%, lifetime 36.8%) were reported in a slightly older group (13–16) using a similar interview schedule and drawing from both urban and rural schools (Kelleher et al. Reference Kelleher, Murtagh, Molloy, Roddy, Clarke, Harley and Cannon2012). Rates of anxiety (13%) and depressive (13%) disorders were more than double the rates from the Challenging Times (CT) study (Kelleher et al. Reference Kelleher, Murtagh, Molloy, Roddy, Clarke, Harley and Cannon2012). Rates of attentional and behavioural disorders (7%) were also higher than the CT study (Kelleher et al. Reference Kelleher, Murtagh, Molloy, Roddy, Clarke, Harley and Cannon2012). The older age of Kelleher’s study cannot account for the higher rate as Coughlan et al. Reference Coughlan, Tiedt, Clarke, Kelleher, Tabish, Molloy, Harley and Cannon(2014) reported equally high rates (31.2%) in a slightly younger cohort (11–13years) (Coughlan et al. Reference Coughlan, Tiedt, Clarke, Kelleher, Tabish, Molloy, Harley and Cannon2014). When they excluded youth with phobias, considering them to be time-limited, potentially less impairing, and rarely needing CAMHS intervention, past month rates fell significantly from 27.4% to 15.4%. However, there was a much smaller reduction in rates of lifetime diagnosis (36.8–31.2%), and rates remained higher than rates reported in the CT study (Lynch et al. Reference Lynch, Mills, Daly and Fitzpatrick2004). Whilst the inner-city location was proposed as a plausible reason to explain the higher SDQ rates observed in the CT when compared to GUI, it is unlikely this can be used to explain lower rates following research interviews.
Variance between studies using similar methodology has also been reported in the UK studies. For example, Deighton and colleagues (Deighton et al. Reference Deighton, Lereya, Casey, Patalay, Humphrey and Wolpert2019) using the SDQ reported rates of psychopathology as high as 42.5% in their sample, higher than reported in other UK studies (Vizard et al. Reference Vizard, Sadler, Ford, Newlove-Delgado, McManus, Marcheselli, Davis, Williams, Leach, Mandalia and Cart-Wright2020), and used this to argue for radically increased service development. When critiqued, this discrepancy was attributed to methodological differences and reporting between studies (Ford & McManus, Reference Ford and McManus2020). Increased reported rates may be due to a true increase in pathology, changes in administrative prevalence, changes in access or acceptance criteria to services. They may also be due to or variations in help seeking, improved screening or increased recognition, leading to existing problems becoming recognized. Increased medicalization of transient and potentially normal emotional states, changing perceptions and personal understanding of health and wellbeing may also contribute to increase self-reported or clinically sought and given diagnosis. All of these factors may influence rates reported by various studies, especially when school cohorts in which other MH programmes have been running, might be used for recruitment.
Given the significant variations reported between studies of broadly similar design, it is difficult to present a unified picture of prevalence of MH disorders among youth in ROI.
As outlined, lower rates of general psychopathology emerged from GUI using SDQ (4.8–6.5%) than UK rates (Vizard et al. Reference Vizard, Sadler, Ford, Newlove-Delgado, McManus, Marcheselli, Davis, Williams, Leach, Mandalia and Cart-Wright2020) and from interview-based studies. Discrepancies in rates of diagnosis based on interview versus self-report is a recognised phenomena. Recent data from UK also alert to discrepancies between prevalence based on questionnaire data (lower) and study specific questions of perceived long-standing MH conditions (suggesting a higher prevalence) (Pitchforth et al. Reference Pitchforth, Fahy, Ford, Wolpert, Viner and Hargreaves2019). Should service planning in ROI therefore be based on GUI estimates alone, this might lead to an underestimate of true need and insufficient services. Given that fewer than half (44%) of those identified as in need of specialist MH services in ROI were accessing them, such underestimates of need will be unhelpful.
Many of the Irish studies found in this review were also limited by reliance on single informant report, data presented without adjustment for attrition or subsample groupings, and lack of adequate sample description such that potential confounders might be considered. For example, rural or urban setting, whether recruitment used an ‘opt in’ or ‘opt out’ design, reporting on response rate for both gate keepers such as schools, as well as response rate among participants. These methodological differences might explain the variance between prevalence rates reported among seemingly similar groups.
Epidemiological estimates of new and existing cases are needed for service planning. Such studies need to be large in order to accurately report on disorders with low prevalence rates and to examine change over time. For this, surveillance surveys have merit, offering a cheaper and more efficient way to gather information on rarer disorders. This methodology has been pioneered by the British Paediatric Surveillance Unit (BPSU) in 1986, which has completed 120 studies (British Paediatric Surveillance Unit team | RCPCH). A ‘report card’ is sent to clinicians requesting specific information on low prevalence clinical cases of interest, thus provided a cost-effective way of collating large amounts of information on aetiology, treatment and outcomes (see: https://www.rcpch.ac.uk/work-we-do/bpsu). Their surveillance has facilitated research into over 100 rare conditions, influencing health policy and clinical care. The search strategy for this review identified some studies from the Child and Adolescent Psychiatry Surveillance System which reported data on child mental health disorders across the UK, including Ireland. However, these had to be excluded as there were no data presented separately for Ireland.
Limitations
This systematic review is subject to some limitations. The heterogeneity in the studies found, including considerable variation in age of study participants, sample selection; mental illness and diagnostic instruments meant a meta-analysis could not be carried out. There was also considerable variation in sample size across included studies, mix of cross-sectional and longitudinal, and quantitative and qualitative methodologies. Therefore, this review presents a narrative synthesis of findings.
Conclusion
Given the pressure to adequately provide for youth with serious and enduring mental health disorders, it is essential to differentiate psychological distress from more severe pathology, and not conflate the two. Use of broad terminology and low cut-off scores can inadvertently inflate prevalence. Robustly conducted epidemiological studies using impairment criteria will help in this regard but such data is currently lacking in ROI. Future studies should employ a two-stage design, with appropriate psychometric questionnaires followed by standardised interview and applying weighted analysis. This will allow the research to establish severity of symptoms, degree of functional impairment, and presence of a moderate-severe mental illness needing specialist treatment. Without routine systematic data collection, it is hard to ensure that the scare resources available are directed to the right services so that children with most need receive appropriate treatment. Given the evidence from other countries of increased prevalence of mental health disorders in youth over time, serial studies are needed. Although variance existed in rates of MH pathology, studies generally agreed that the majority of youth identified as meeting criteria for a psychiatric disorder were not receiving professional help and fewer still had contact with CAMHS. There is an urgent need for more extensive epidemiological surveys, with clear operational criteria for clinically impairing mental health difficulties to be conducted. This is essential to understand potential demand on services and the nature of illness such that services may adapt to meet the needs of their population.
Figure 1. PRISMA. *Reasons for exclusion: 1 = Population not ROI or cannot separate; 2 = Population not under 18 or cannot separate; 3 = population is a specific vulnerable group, clinical setting not general population; 4 = no quantitative data for ROI; 5 = data not related to mental illness or no validated psychometric instrument used.
Table 4. Rates of ‘at risk’ psychopathology and MH Diagnosis in Challenging Times study
All analysis were weighted to prevent an over-estimate given the interviews were conducted with a higher % of an at-risk group. SDQ: Strengths and Difficulties Questionnaire; CDI: Child Depression Inventory; K-SADS-PL: Kiddie Schedule for Affective disorders Past month and Lifetime version; MH: Mental health; ADHD: Attention Deficit Hyperactivity Disorder; CD: Conduct Disorder; ODD: Oppositional Defiant Disorder.
Table 5. General and specific psychopathology prevalence rates
SEYLE: Saving and Empowering Young Lives in Europe; SDQ: Strengths and Difficulties Questionnaire; K-SADS: Kiddie Schedule for Affective disorders; HBSC: Health behaviour in School-aged Children; BMI: Body mass index; EAT-26: Eating Attitude test-26; CES-D: Centre for Epidemiological Studies-Depression Scale; YSR: Youth Self-report.
Table 6. Mental health screening tools and interviews for children and adolescents
Supplementary material
To view supplementary material for this article, please visit http://doi.org/10.1017/ipm.2022.46
Author contribution
This study was conducted as a Summer Student Research Attachment (SL). All authors contributed to data selection, extraction and paper write up.
Financial support
This research received no specific grant from any funding agency, commercial or not-for-profit sectors.
Conflict of interest
The authors confirm they have no conflict of interest to declare.
Ethical standards
The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committee on human experimentation with the Helsinki Declaration of 1975, as revised in 2008.
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