I discuss the right to participate in science, which is part of the UN Declaration of Human Rights (1948) and the International Covenant on Economic Social and Cultural Rights (1966). Building on my previous work on this right as an ‘epistemic-cultural’ right, in this paper my goal is to clarify how fulfilling this right requires engaging with varieties of local knowledges that are too often severed in scientific narratives. I tease out three main varieties of local knowledges and highlight their distinctive features and their intersectionalities. In the second part of the paper, I argue that a more careful appreciation of varieties of local knowledges is not only key for the fulfilment of the right to participate in science but also for other human rights. I focus my attention here selectively on the right to food, and right to clean water. I conclude by highlighting the implications of this discussion for ongoing legal debates on rights of nature.