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Hypertrophic cardiomyopathy in Duchenne muscular dystrophy: a case series

Published online by Cambridge University Press:  13 November 2024

Eleanor Greiner Open the ORCID record for Eleanor Greiner [Opens in a new window] ,
Nobuyuki Ikeda ,
Thomas D. Ryan Open the ORCID record for Thomas D. Ryan [Opens in a new window]  and
Chet R. Villa
Eleanor Greiner
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
Nobuyuki Ikeda
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
Thomas D. Ryan
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
Chet R. Villa*
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
*
Corresponding author: Chet R. Villa; Email: [email protected]
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Abstract

Duchenne muscular dystrophy is characterised by fibrofatty replacement of muscle, resulting in dilated cardiomyopathy. Hypertrophic cardiomyopathy affects 1:200–1:500 people and is characterised by asymmetric ventricular septal hypertrophy. To date, there have been two separately reported cases describing the combined pathology of these disorders. Herein, we expand upon these reports with a case series describing longitudinal findings in three patients with Duchenne muscular dystrophy who developed hypertrophic cardiomyopathy.

Keywords

Cardiomyopathymuscular dystrophyhypertrophy
Type
Brief Report
Information
Cardiology in the Young , Volume 34 , Issue 10 , October 2024 , pp. 2272 - 2274
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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