Southampton provides tertiary services for a population of approximately 650 000 children. As part of the complex treatment of children referred to Southampton, a number require Parenteral Nutrition (PN) for greater than 28 days. We describe the trends in prolonged PN usage at our centre over the last 10 years.

Children who received PN for >28 days were identified from PN prescriptions managed by pharmacy. Data was collected retrospectively from patient records. Babies who received PN solely on the neonatal unit were excluded as were those who only received PN on the Paediatric Intensive Care Unit.

74 (35 female) children were identified having 81 episodes of PN >28 days. New and total number of patients per year, are shown in the table. Median age at start of PN episode was 2.9 years with range of 0 to 18 years. Duration of PN ranged from 29 days to 2108 days (6 years), median duration was 63 days. 30 children had 31 episodes of PN >90 days. 57 children came off PN, ten are currently at home on PN, four children died; two from their oncological diagnosis and two had intractable gut disease. Two children were transferred to adults and one to another centre. In total 18 children received home PN in this 10 year period.19 children received PN due to complications of oncological diagnoses or treatment, 16 due to surgical intra-abdominal crises, 8 for Inflammatory Bowel Disease, 4 for Hirschprung's, 9 for enteropathies and 11 for congenital defects including 7 with gastroschisis and 7 for other reasons.

Prolonged use of PN has increased over the last 10 years with a growing number of children receiving PN at home. Despite increasing numbers, the majority of children come off PN. There is a need for collaborative working with adult PN teams as some children require transfer to adult services. The management of these children is complex and requires a dedicated multidisciplinary team. A sustained rise in incident cases would have implications for those planning regional and national services.