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Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes

Published online by Cambridge University Press:  22 March 2022

Aki Nikolaidis ,
Charlotte Heleniak ,
Andrea Fields ,
Paul A. Bloom ,
Michelle VanTieghem ,
Anna Vannucci ,
Nicolas L. Camacho ,
Tricia Choy ,
Lisa Gibson  and
Chelsea Harmon
...Show all authors
Aki Nikolaidis*
Affiliation:
Child Mind Institute, New York, NY, USA
Charlotte Heleniak
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Andrea Fields
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Paul A. Bloom
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Michelle VanTieghem
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Anna Vannucci
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Nicolas L. Camacho
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Tricia Choy
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Lisa Gibson
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Chelsea Harmon
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Syntia S. Hadis
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Ian J. Douglas
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
Michael P. Milham
Affiliation:
Child Mind Institute, New York, NY, USA
Nim Tottenham
Affiliation:
Department of Psychology, Columbia University, New York, NY, USA
*
Corresponding author: Aki Nikolaidis, email: [email protected]
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Abstract

Early psychosocial adversities exist at many levels, including caregiving-related, extrafamilial, and sociodemographic, which despite their high interrelatedness may have unique impacts on development. In this paper, we focus on caregiving-related early adversities (crEAs) and parse the heterogeneity of crEAs via data reduction techniques that identify experiential cooccurrences. Using network science, we characterized crEA cooccurrences to represent the comorbidity of crEA experiences across a sample of school-age children (n = 258; 6–12 years old) with a history of crEAs. crEA dimensions (variable level) and crEA subtypes (subject level) were identified using parallel factor analysis/principal component analysis and graph-based Louvain community detection. Bagging enhancement with cross-validation provided estimates of robustness. These data-driven dimensions/subtypes showed evidence of stability, transcended traditional sociolegally defined groups, were more homogenous than sociolegally defined groups, and reduced statistical correlations with sociodemographic factors. Finally, random forests showed both unique and common predictive importance of the crEA dimensions/subtypes for childhood mental health symptoms and academic skills. These data-driven outcomes provide additional tools and recommendations for crEA data reduction to inform precision medicine efforts in this area.

Keywords

caregiving related early adversitiesheterogeneitypredictionsubtyping
Type
Special Issue Article
Information
Development and Psychopathology , Volume 34 , Issue 2: Special Issue: Dimensions of early experience and adaptive and maladaptive development , May 2022 , pp. 621 - 634
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© The Author(s), 2022. Published by Cambridge University Press

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References

Aber, J. L. (2013). Family and community level effects. In C. A. Nelson (Ed.), Threats to optimal development: Integrating biological, psychological, and social risk factors: The Minnesota symposia on child psychology (vol. 27, pp. 229). Psychology Press.Google Scholar
Achenbach, T. M., & Rescorla, L. A. Eds (2001). Manual for the Aseba school-age forms & profiles. University of Vermont, Research Center for Children, Youth, & Families.Google Scholar
Baram, T. Z., Davis, E. P., Obenaus, A., Sandman, C. A., Small, S. L., Solodkin, A.…Stern, H. (2012). Fragmentation and unpredictability of early-life experience in mental disorders. American Journal of Psychiatry, 169(9), 907–915. https://doi.org/10.1176/appi.ajp.2012.11091347 CrossRefGoogle ScholarPubMed
Barnet, O., Miller-Perrin, C. L., & Perrin, R. D. (2005). Child psychological maltreatment. In O. Barnett, C. L. Miller-Perrin, & R. D. Perrin (Eds.), Family violence across the lifespan: An introduction (2nd edn., pp. 151–178). Sage Publications.Google Scholar
Belsky, J., Schlomer, G. L., & Ellis, B. J. (2012). Beyond cumulative risk: Distinguishing harshness and unpredictability as determinants of parenting and early life history strategy. Developmental Psychology, 48(3), 662. https://doi.org/10.1037/a0024454 CrossRefGoogle ScholarPubMed
Benjet, C., Borges, G., & Medina-Mora, M. E. (2010). Chronic childhood adversity and onset of psychopathology during three life stages: Childhood, adolescence and adulthood. Journal of Psychiatric Research, 44(11), 732–740. https://doi.org/10.1016/j.jpsychires.2010.01.004 CrossRefGoogle Scholar
Berzenski, S. R., & Yates, T. M. (2011). Classes and consequences of multiple maltreatment: A person-centered analysis. Child Maltreatment, 16(4), 250–261. https://doi.org/10.1177/1077559511428353 CrossRefGoogle ScholarPubMed
Blondel, V. D., Guillaume, J.-L., Lambiotte, R., & Lefebvre, E. (2008). Fast unfolding of communities in large networks. Journal of Statistical Mechanics: Theory and Experiment, 2008(10), P10008.CrossRefGoogle Scholar
Bowlby, J. (1977). The making and breaking of affectional bonds: Ii. Some Principles of psychotherapy: The fiftieth Maudsley Lecture (expanded version). British Journal of Psychiatry, 130(5), 421–431. https://doi.org/10.1192/bjp.130.5.421 CrossRefGoogle Scholar
Bowlby, J., Ainsworth, M., Boston, M., & Rosenbluth, D. (1956). The effects of mother-child separation: A follow-up study. British Journal of Medical Psychology, 29(3-4), 211–247. https://doi.org/10.1111/j.2044-8341.1956.tb00915.x CrossRefGoogle Scholar
Breiman, L. (1996). Bagging predictors. Machine Learning, 24(2), 123–140.CrossRefGoogle Scholar
Brown, S. M., Rienks, S., McCrae, J. S., & Watamura, S. E. (2019). The co-occurrence of adverse childhood experiences among children investigated for child maltreatment: A latent class analysis. Child Abuse and Neglect, 87, 18–27. https://doi.org/10.1016/j.chiabu.2017.11.010 CrossRefGoogle ScholarPubMed
Chabernaud, C., Mennes, M., Kelly, C., Nooner, K., Di Martino, A., Castellanos, F. X.…Milham, M. P. (2012). Dimensional brain-behavior relationships in children with attention-deficit/hyperactivity disorder. Biological Psychiatry, 71(5), 434–442. https://doi.org/10.1016/j.biopsych.2011.08.013 CrossRefGoogle ScholarPubMed
Cicchetti, D., & Blender, J. A. (2004). A multiple-levels-of-analysis approach to the study of developmental processes in maltreated children. Procedings of the National Academy of Sciences of the United States of America, 101(50), 17325–17326. https://doi.org/10.1073/pnas.0408033101 CrossRefGoogle Scholar
Cicchetti, D., & Rizley, R. (1981). Developmental perspectives on the etiology, intergenerational transmission, and sequelae of child maltreatment. New Directions for Child and Adolescent Development, 1981(11), 31–55. https://doi.org/10.1002/cd.23219811104 CrossRefGoogle Scholar
Cicchetti, D., & Rogosch, F. A. (1996). Equifinality and multifinality in developmental psychopathology. Development and Psychopathology, 8(4), 597–600. https://doi.org/10.1017/S0954579400007318 CrossRefGoogle Scholar
Cicchetti, D., & Toth, S. L. (1993). Advances in applied developmental psychology: Child abuse, child development and social policy (pp. 7–73). Ablex Publishing Corp.Google Scholar
Cicchetti, D., & Toth, S. L. (2005). Child maltreatment. Annual Review of Clinical Psychology, 1, 409–438. https://doi.org/10.1146/annurev.clinpsy.1.102803.144029 CrossRefGoogle ScholarPubMed
Cicchetti, D., Toth, S. L., & Manly, J. T (2003). Maternal Maltreatment Classification Interview, Unpublished manuscript, Mt. Hope Family Center, Rochester, NY..Google Scholar
Cicchetti, D., Toth, S. L., & Maughan, A. (2000). An ecological-transactional model of child maltreatment. In Sameroff, A. J., Lewis, M., & Miller, S. M. (Eds.), Handbook of developmental psychopathology. Kluwer Academic Publishers, https://doi.org/10.1007/978-1-4615-4163-9_37 Google Scholar
Clark, C., Caldwell, T., Power, C., & Stansfeld, S. A. (2010). Does the influence of childhood adversity on psychopathology persist across the lifecourse? A 45-year prospective epidemiologic study. Annals of Epidemiology, 20(5), 385–394. https://doi.org/10.1016/j.annepidem.2010.02.008 CrossRefGoogle ScholarPubMed
Cohodes, E. M., Kitt, E. R., Baskin-Sommers, A., & Gee, D. G. (2021). Influences of early-life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology, 63, 153–172. https://doi.org/10.1002/dev.21969 CrossRefGoogle ScholarPubMed
Cowell, R. A., Cicchetti, D., Rogosch, F. A., & Toth, S. L. (2015). Childhood maltreatment and its effect on neurocognitive functioning: Timing and chronicity matter. Development and Psychopathology, 27(2), 521–533. https://doi.org/10.1017/S0954579415000139 CrossRefGoogle ScholarPubMed
Fair, D. A., Nigg, J. T., Iyer, S., Bathula, D., Mills, K. L., Dosenbach, N. U.…Milham, M. P. (2012). Distinct neural signatures detected for adhd subtypes after controlling for micro-movements in resting state functional connectivity MRI data. Frontiers in Systems Neuroscience, 6, 80. https://doi.org/10.3389/fnsys.2012.00080 Google ScholarPubMed
Feczko, E., & Fair, D. A. (2020). Methods and challenges for assessing heterogeneity. Biological Psychiatry, 88(1), 9–17. https://doi.org/10.1016/j.biopsych.2020.02.015 CrossRefGoogle ScholarPubMed
Feczko, E., Miranda-Dominguez, O., Marr, M., Graham, A. M., Nigg, J. T., & Fair, D. A. (2019). The heterogeneity problem: Approaches to identify psychiatric subtypes. Trends in Cognitive Sciences, 23(7), 584–601. https://doi.org/10.1016/j.tics.2019.03.009 CrossRefGoogle ScholarPubMed
Finkelhor, D., Ormrod, R. K., & Turner, H. A. (2007). Poly-victimization: A neglected component in child victimization. Child Abuse and Neglect, 31(1), 7–26. https://doi.org/10.1016/j.chiabu.2006.06.008 CrossRefGoogle ScholarPubMed
Fluke, J. D., Yuan, Y. Y., & Edwards, M. (1999). Recurrence of maltreatment: An application of the national child abuse and neglect data system (Ncands). Child Abuse and Neglect, 23(7), 633–650. https://doi.org/10.1016/s0145-2134(99)00039-3 CrossRefGoogle Scholar
Ford, J. D., Racusin, R., Rogers, K., Ellis, C., Schiffman, J., Ribbe, D.…Edwards, J. (2002). Traumatic Events Screening Inventory for Children (TESI-C) version 8.4. National Center for PTSD and Dartmouth Child Psychiatry Research Group, Dartmouth VT.Google Scholar
Green, J. G., McLaughlin, K. A., Berglund, P. A., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M.…Kessler, R. C. (2010). Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: Associations with first onset of Dsm-Iv disorders. Archives of General Psychiatry, 67(2), 113–123. https://doi.org/10.1001/archgenpsychiatry.2009.186 CrossRefGoogle ScholarPubMed
Green, M. J. (2014). Latent class analysis was accurate but sensitive in data simulations. Journal of Clinical Epidemiology, 67(10), 1157–1162. https://doi.org/10.1016/j.jclinepi.2014.05.005 CrossRefGoogle ScholarPubMed
Groark, C. J., & McCall, R. B. (2011). Improving institutions: Can we? Should we? How? International Journal of Child & Family Welfare, 14(2), 64–72.Google Scholar
Groark, C. J., McCall, R. B., Fish, L., & Team, W. C. I. E. (2011). Characteristics of environments, caregivers, and children in three central american orphanages. Infant Mental Health Journal, 32(2), 232–250. https://doi.org/10.1002/imhj.20292 CrossRefGoogle ScholarPubMed
Gunnar, M. R., Bruce, J., & Grotevant, H. D. (2000). International adoption of institutionally reared children: Research and policy. Development and Psychopathology, 12(4), 677–693. https://doi.org/10.1017/s0954579400004077 CrossRefGoogle ScholarPubMed
Hanson, J. L., Nacewicz, B. M., Sutterer, M. J., Cayo, A. A., Schaefer, S. M., Rudolph, K. D.…Davidson, R. J. (2015). Behavioral problems after early life stress: Contributions of the hippocampus and amygdala. Biological Psychiatry, 77(4), 314–323. https://doi.org/10.1016/j.biopsych.2014.04.020 CrossRefGoogle ScholarPubMed
Hart, S. N., & Brassard, M. R. (1987). A major threat to children’s mental health: Psychological maltreatment. American Psychologist, 42(2), 160–165. https://doi.org/10.1037//0003-066x.42.2.160 CrossRefGoogle Scholar
Hazen, A. L., Connelly, C. D., Roesch, S. C., Hough, R. L., & Landsverk, J. A. (2009). Child maltreatment profiles and adjustment problems in high-risk adolescents. Journal of Interpersonal Violence, 24(2), 361–378. https://doi.org/10.1177/0886260508316476 CrossRefGoogle ScholarPubMed
Herzog, J. I., Thome, J., Demirakca, T., Koppe, G., Ende, G., Lis, S.…Steil, R. (2020). Influence of severity of type and timing of retrospectively reported childhood maltreatment on female amygdala and hippocampal volume. Scientific Reports, 10(1), 1–10. https://doi.org/10.1038/s41598-020-57490-0 CrossRefGoogle ScholarPubMed
Horn, J. L. (1965). A rationale and test for the number of factors in factor analysis. Psychometrika, 30, 179–185. https://doi.org/10.1007/BF02289447 CrossRefGoogle ScholarPubMed
Hornor, G. (2012). Emotional maltreatment. Journal of Pediatric Health Care, 26(6), 436–442. https://doi.org/10.1016/j.pedhc.2011.05.004 CrossRefGoogle ScholarPubMed
Infurna, M. R., Reichl, C., Parzer, P., Schimmenti, A., Bifulco, A., & Kaess, M. (2016). Associations between depression and specific childhood experiences of abuse and neglect: A meta-analysis. Journal of Affective Disorders, 190, 47–55. https://doi.org/10.1016/j.jad.2015.09.006 CrossRefGoogle ScholarPubMed
Insel, T. R., & Cuthbert, B. N. (2015). Medicine. Brain disorders? Precisely. Science, 348(6234), 499–500, https://doi.org/10.1126/science.aab2358,CrossRefGoogle ScholarPubMed
Ivy, A. S., Brunson, K. L., Sandman, C., & Baram, T. Z. (2008). Dysfunctional nurturing behavior in rat dams with limited access to nesting material: A clinically relevant model for early-life stress. Neuroscience, 154(3), 1132–1142. https://doi.org/10.1016/j.neuroscience.2008.04.019 CrossRefGoogle ScholarPubMed
Karalunas, S. L., Fair, D., Musser, E. D., Aykes, K., Iyer, S. P., & Nigg, J. T. (2014). Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: Toward biologically based nosologic criteria. JAMA Psychiatry, 71(9), 1015–1024. https://doi.org/10.1001/jamapsychiatry.2014.763 CrossRefGoogle ScholarPubMed
Kessler, R. C., McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M.…Williams, D. R. (2010). Childhood adversities and adult psychopathology in the who world mental health surveys. British Journal of Psychiatry, 197(5), 378–385. https://doi.org/10.1192/bjp.bp.110.080499 CrossRefGoogle ScholarPubMed
Kim, H., & Drake, B. (2018). Child maltreatment risk as a function of poverty and race/ethnicity in the USA. International Journal of Epidemiology, 47(3), 780–787. https://doi.org/10.1093/ije/dyx280 CrossRefGoogle Scholar
Kim, K., Mennen, F. E., & Trickett, P. K. (2017). Patterns and correlates of co-occurrence among multiple types of child maltreatment. Child and Family Social Work, 22(1), 492–502. https://doi.org/10.1111/cfs.12268 CrossRefGoogle ScholarPubMed
Lacey, R. E., Howe, L. D., Kelly-Irving, M., Bartley, M., & Kelly, Y. (In Press). The Clustering of Adverse Childhood Experiences in the Avon Longitudinal Study of Parents and Children: Are Gender and Poverty Important? Journal of Interpersonal Violence. https://doi.org/10.1177/0886260520935096 Google Scholar
Lambert, H. K., King, K. M., Monahan, K. C., & McLaughlin, K. A. (2017). Differential associations of threat and deprivation with emotion regulation and cognitive control in adolescence. Development and Psychopathology, 29(3), 929–940. https://doi.org/10.1017/S0954579416000584 CrossRefGoogle ScholarPubMed
Maguire-Jack, K., Lanier, P., & Lombardi, B. (2020). Investigating racial differences in clusters of adverse childhood experiences. American Journal of Orthopsychiatry, 90(1), 106–114. https://doi.org/10.1037/ort0000405 CrossRefGoogle ScholarPubMed
Manly, J. T. (2005). Advances in research definitions of child maltreatment. Child Abuse and Neglect, 29(5), 425–439. https://doi.org/10.1016/j.chiabu.2005.04.001 CrossRefGoogle Scholar
Manly, J. T., Kim, J. E., Rogosch, F. A., & Cicchetti, D. (2001). Dimensions of child maltreatment and children’s adjustment: Contributions of developmental timing and subtype. Development and Psychopathology, 13(4), 759–782. https://doi.org/10.1017/S0954579401004023 CrossRefGoogle ScholarPubMed
Manly, J. T., Oshri, A., Lynch, M., Herzog, M., & Wortel, S. (2013). Child neglect and the development of externalizing behavior problems: Associations with maternal drug dependence and neighborhood crime. Child Maltreatment, 18(1), 17–29. https://doi.org/10.1177/1077559512464119 CrossRefGoogle ScholarPubMed
Matsumoto, M., Piersiak, H., Letterie, M., & Humphreys, K. (2020). Population-based estimates of associations between child maltreatment type: A meta-analysis. PsyArXiv, https://doi.org/10.31234/osf.io/cv5qw,Google Scholar
McLaughlin, K. A., Greif Green, J., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., & Kessler, R. C. (2012). Childhood adversities and first onset of psychiatric disorders in a national sample of US adolescents. Archives of General Psychiatry, 69(11), 1151–1160. https://doi.org/10.1001/archgenpsychiatry.2011.2277 CrossRefGoogle Scholar
McLaughlin, K. A., Sheridan, M., Humphreys, K. L., Belsky, J., & Ellis, B. J. (2021). The value of dimensional models of early experience: Thinking clearly about concepts and categories. Perspectives on Psychological Science, 16(6), 1463–1472. https://doi.org/doi.org/10.1177/1745691621992346 CrossRefGoogle ScholarPubMed
McLaughlin, K. A., Sheridan, M. A., & Lambert, H. K. (2014). Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience. Neuroscience and Biobehavioral Reviews, 47, 578–591. https://doi.org/10.1016/j.neubiorev.2014.10.012 CrossRefGoogle ScholarPubMed
Ney, P. G., Fung, T., & Wickett, A. R. (1994). The worst combinations of child abuse and neglect. Child Abuse and Neglect, 18(9), 705–714. https://doi.org/10.1016/0145-2134(94)00037-9 CrossRefGoogle ScholarPubMed
Nikolaidis, A., DeRosa, J., Kass, M., Droney, I., Alexander, L., Di Martino, A.…Paksarian, D. (2021). Heterogeneity in Covid-19 pandemic-induced lifestyle stressors and predicts future mental health in adults and children in the US and UK. medRxiv, https://doi.org/10.1101/2021.08.10.21261860,Google ScholarPubMed
Nikolaidis, A., Paksarian, D., Alexander, L., Derosa, J., Dunn, J., Nielson, D. M.…Merikangas, K. R. (2021). The Coronavirus Health and Impact Survey (CRISIS) reveals reproducible correlates of pandemic-related mood states across the atlantic. Scientific Reports, 11(1), 8139. https://doi.org/10.1038/s41598-021-87270-3 CrossRefGoogle ScholarPubMed
Nikolaidis, A., Solon Heinsfeld, A., Xu, T., Bellec, P., Vogelstein, J., & Milham, M. (2020). Bagging improves reproducibility of functional parcellation of the human brain. Neuroimage, 214, 116678. https://doi.org/10.1016/j.neuroimage.2020.116678 CrossRefGoogle ScholarPubMed
Pears, K. C., Kim, H. K., & Fisher, P. A. (2008). Psychosocial and cognitive functioning of children with specific profiles of maltreatment. Child Abuse and Neglect, 32(10), 958–971, https://doi.org/10.1016/j.chiabu.2007.12.009,CrossRefGoogle ScholarPubMed
Petrenko, C. L., Friend, A., Garrido, E. F., Taussig, H. N., & Culhane, S. E. (2012). Does subtype matter? Assessing the effects of maltreatment on functioning in preadolescent youth in out-of-home care. Child Abuse and Neglect, 36(9), 633–644, https://doi.org/10.1016/j.chiabu.2012.07.001,CrossRefGoogle ScholarPubMed
Sameroff, A. J., & Chandler, M. J. (1975). Reproductive risk and the continuum of caretaking casualty. Review of Child Development Research, 4, 187–244.Google Scholar
Schalinski, I., Teicher, M. H., Nischk, D., Hinderer, E., Muller, O., & Rockstroh, B. (2016). Type and timing of adverse childhood experiences differentially affect severity of PTSD, dissociative and depressive symptoms in adult inpatients. BMC Psychiatry, 16, 295. https://doi.org/10.1186/s12888-016-1004-5 CrossRefGoogle ScholarPubMed
Scott, B. G., Burke, N. J., Weems, C. F., Hellman, J. L., & Carrión, V. G. (2013). The interrelation of adverse childhood experiences within an at-risk pediatric sample. Journal of Child & Adolescent Trauma, 6(3), 217–229.CrossRefGoogle Scholar
Sheridan, M. A., & McLaughlin, K. A. (2014). Dimensions of early experience and neural development: Deprivation and threat. Trends in Cognitive Sciences, 18(11), 580–585. https://doi.org/10.1016/j.tics.2014.09.001 CrossRefGoogle ScholarPubMed
Sheridan, M. A., Shi, F., Miller, A. B., Salhi, C., & McLaughlin, K. A. (2020). Network structure reveals clusters of associations between childhood adversities and development outcomes. Developmental Science, 23(5), e12934. https://doi.org/10.1111/desc.12934 CrossRefGoogle ScholarPubMed
Shorter, E., & Tyrer, P. (2003). Separation of anxiety and depressive disorders: Blind alley in psychopharmacology and classification of disease. British Medical Journal, 327(7407), 158–160. https://doi.org/10.1136/bmj.327.7407.158 CrossRefGoogle ScholarPubMed
Sierau, S., Brand, T., Manly, J. T., Schlesier-Michel, A., Klein, A. M., Andreas, A.…White, L. O. (2017). A multisource approach to assessing child maltreatment from records, caregivers, and children. Child Maltreatment, 22(1), 45–57. https://doi.org/10.1177/1077559516675724 CrossRefGoogle Scholar
Smith, K. E., & Pollak, S. D. (2021). Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity. Perspectives on Psychological Science, 16(1), 67–93. https://doi.org/10.1177/1745691620920725 CrossRefGoogle ScholarPubMed
Spinazzola, J., Hodgdon, H., Liang, L.-J., Ford, J. D., Layne, C. M., Pynoos, R.…Kisiel, C. (2014). Unseen wounds: The contribution of psychological maltreatment to child and adolescent mental health and risk outcomes. Psychological Trauma: Theory, Research, Practice, and Policy, 6(S1), S18. https://doi.org/10.1037/a0037766 CrossRefGoogle Scholar
Tang, S., Sun, N., Floris, D. L., Zhang, X., Di Martino, A., & Yeo, B. T. T. (2020). Reconciling dimensional and categorical models of autism heterogeneity: A brain connectomics and behavioral study. Biological Psychiatry, 87(12), 1071–1082. https://doi.org/10.1016/j.biopsych.2019.11.009 CrossRefGoogle ScholarPubMed
Tonmyr, L., Draca, J., Crain, J., & Macmillan, H. L. (2011). Measurement of emotional/psychological child maltreatment: A review. Child Abuse and Neglect, 35(10), 767–782. https://doi.org/10.1016/j.chiabu.2011.04.011 CrossRefGoogle ScholarPubMed
Tottenham, N. (2020). Neural meaning making, prediction, and prefrontal–subcortical development following early adverse caregiving. Development and Psychopathology, 32(5), 1563–1578. https://doi.org/10.1017/S0954579420001169 CrossRefGoogle Scholar
Trickett, P. K., & McBride-Chang, C. (1995). The developmental impact of different forms of child abuse and neglect. Developmental Review, 15(3), 311–337. https://doi.org/10.1006/drev.1995.1012 CrossRefGoogle Scholar
Trickett, P. K., Mennen, F. E., Kim, K., & Sang, J. (2009). Emotional abuse in a sample of multiply maltreated, urban young adolescents: Issues of definition and identification. Child Abuse and Neglect, 33(1), 27–35. https://doi.org/10.1016/j.chiabu.2008.12.003 CrossRefGoogle Scholar
van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Duschinsky, R., Fox, N. A., Goldman, P. S., Gunnar, M. R.…Skinner, G. C. (2020). Institutionalisation and deinstitutionalisation of children 1: A systematic and integrative review of evidence regarding effects on development. The Lancet Psychiatry, 7(8), 703–720. https://doi.org/10.1016/S2215-0366(19)30399-2 CrossRefGoogle ScholarPubMed
Vaughan-Jensen, J., Adame, C., McLean, L., & Gámez, B. (2011). Test review: D. Wechsler Wechsler Individual Achievement Test. San Antonio, TX: Pearson, 2009. Journal of Psychoeducational Assessment, 29(3), 286–291, https://doi.org/10.1177/0734282910385645,CrossRefGoogle Scholar
Vermunt, J. K., & Magidson, J. (2004). Latent class analysis. The Sage Encyclopedia of Social Sciences Research Methods, 2, 549–553.Google Scholar
Wade, M., Fox, N. A., Zeanah, C. H., & Nelson, C. A. (3rd, 2019). Long-term effects of institutional rearing, foster care, and brain activity on memory and executive functioning. Proceedings of the National Academy of Sciences of the United States of America, 116(5), 1808–1813. https://doi.org/10.1073/pnas.1809145116 CrossRefGoogle ScholarPubMed
Wardenaar, K. J., & de Jonge, P. (2013). Diagnostic heterogeneity in psychiatry: Towards an empirical solution. BMC Medicine, 11, 201. https://doi.org/10.1186/1741-7015-11-201 CrossRefGoogle ScholarPubMed
Warmingham, J. M., Handley, E. D., Rogosch, F. A., Manly, J. T., & Cicchetti, D. (2019). Identifying maltreatment subgroups with patterns of maltreatment subtype and chronicity: A latent class analysis approach. Child Abuse and Neglect, 87, 28–39. https://doi.org/10.1016/j.chiabu.2018.08.013 CrossRefGoogle ScholarPubMed
Wechsler, D. (1999). The Wechsler abbreviated scale of intelligence. The Psychological Corporation.Google Scholar
Wolfe, D. A. (2018). Why polyvictimization matters. Journal of Interpersonal Violence, 33(5), 832–837.CrossRefGoogle ScholarPubMed
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