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Should we reconsider how we manage mild obstructive sleep apnoea?

Published online by Cambridge University Press:  24 August 2023

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Abstract

Type
Editorial
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

Although the need for treatment of moderate or severe obstructive sleep apnoea (OSA) is established, treatment of mild OSA is controversial, and is generally managed with simple lifestyle measures, with consideration given to a dental appliance.Reference Sahni, Arora, Bansal, Reddy, Malhotra and Virk1 It is difficult to justify subjecting patients with mild OSA to extensive treatment, especially when there is no conclusive impact of treatment on patients’ morbidity and mortality. However, if it is proven that mild OSA progresses to moderate or severe OSA, this then raises the need for a different approach in managing mild OSA.

In this month's issue of The Journal of Laryngology, Fong et al. provide a systematic review of the current literature and analyse the critical question: does mild OSA progress significantly if left untreated?Reference Fong, Tay, Soh, Fook, Li and Phua2 Specifically, they aimed to examine the temporal pattern of OSA changes over time, and identify any predictors of progression.

The authors found that although untreated mild OSA does show a gradual increase in the Apnoea Hypopnea Index, or Respiratory Disturbance Index, over 53.1 months, this rate of increase slowly plateaus, and does not progress across categories into moderate, or severe, OSA.Reference Fong, Tay, Soh, Fook, Li and Phua2 The authors therefore conclude that it is difficult to justify the treatment of mild OSA from the standpoint of disease progression. A study published last year also confirmed at the molecular level less severe airway inflammation in mild OSA patients compared with moderate to severe OSA.Reference Lin, Wang, Chiu, Sun, Lin and Tzeng3 Additionally, Fong et al.Reference Fong, Tay, Soh, Fook, Li and Phua2 found that predictors for disease progression in mild obstructive sleep apnoea are: age of less than 60 years and a baseline body mass index of less than 25 kg/m2.

The importance of the association between hearing loss and cognitive impairment is highlighted once again in a manuscript by Kim et al. in this month's issue,Reference Kim, Jin, Choi and Kwak4 which follows last year's prize-winning systematic review.Reference Lau, Dimitriadis, Mitchell, Martyn-St-James, Hind and Ray5 The authors conclude that hearing evaluations should be included in cognitive assessments, and that test performance should be carefully interpreted in individuals with hearing loss to avoid overestimating cognitive decline.

Finally, a study by Jegatheeswaran et al. compares disposable with reusable nasendoscopes.Reference Jegatheeswaran, Oungpasuk, Choi, Nakhoul, Gokani and Espehana6 Although a small study, the authors found that trainees’ overall satisfaction with disposable and reusable fibre-optic nasendoscopes is comparable. In agreement with other studies, cost analysis favours disposable scopes in the short term and/or in departments with low rates of utilisation, and reusable fibre-optic nasendoscopes in the long term.Reference Morgan, Elsayed, Ramakrishnan, McGlashan, Whynes and McCahon7

References

Sahni, N, Arora, K, Bansal, S, Reddy, GVN, Malhotra, S, Virk, RS. Impact of lifestyle modifications on snoring and mild sleep apnoea patients. J Laryngol Otol 2021;135:892–6CrossRefGoogle ScholarPubMed
Fong, PY, Tay, ZY, Soh, RY, Fook, SMC, Li, HH, Phua, CQ. Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression. J Laryngol Otol 2023;137:828–39Google Scholar
Lin, CC, Wang, YP, Chiu, CH, Sun, YK, Lin, MW, Tzeng, IS. Molecular signalling involved in upper airway remodelling is enhanced in patients with obstructive sleep apnoea. J Laryngol Otol 2022;136:1096–104CrossRefGoogle ScholarPubMed
Kim, MW, Jin, MH, Choi, JY, Kwak, MY. Potential overestimation of cognitive impairment because of hearing loss: impact of test modalities on cognitive test scores. J Laryngol Otol 2023;137:845–50Google Scholar
Lau, K, Dimitriadis, PA, Mitchell, C, Martyn-St-James, M, Hind, D, Ray, J. Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies. J Laryngol Otol;136:103–18CrossRefGoogle Scholar
Jegatheeswaran, L, Oungpasuk, K, Choi, B, Nakhoul, M, Gokani, S, Espehana, A et al. Disposable versus reusable fibre-optic nasendoscopes: a national survey of UK ENT surgical trainees and a single-centre cost-analysis. J Laryngol Otol 2023;137:866–72Google Scholar
Morgan, O, Elsayed, M, Ramakrishnan, Y, McGlashan, J, Whynes, D, McCahon, R. Cost-comparison study of reusable and disposable rhinolaryngoscopes in a large English teaching hospital. J Laryngol Otol 2023;137:541–5CrossRefGoogle Scholar