Hostname: page-component-55f67697df-xlmdk Total loading time: 0 Render date: 2025-05-08T17:43:43.470Z Has data issue: false hasContentIssue false

Emergent veno-arterial extra-corporeal membrane oxygenator support for refractory acute myocarditis in paediatric patients

Published online by Cambridge University Press:  27 September 2024

Mimoza Maldi*
Affiliation:
Congenital Cardiac Surgery De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
Guido M. Olivieri
Affiliation:
Cardiac Surgery and Heart Transplant De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
Simone Ghiselli
Affiliation:
Congenital Cardiac Surgery De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
Andrea Busti
Affiliation:
Congenital Cardiac Surgery De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
Stefano M. Marianeschi
Affiliation:
Congenital Cardiac Surgery De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
*
Corresponding author: M. Maldi; Email: [email protected]

Abstract

Acute myocarditis leading to severe heart failure in paediatric patients is an uncommon but potentially life-threatening condition. The prompt implant of mechanical circulatory devices such as veno-arterial extra-corporeal membrane oxygenation remains the best treatment option to restore an adequate perfusion and improve patient survival in case of refractory cardiogenic shock cases. While few reports describe the in-hospital course of this dramatic disease, with an in-hospital mortality under veno-arterial extra-corporeal membrane oxygenation support around 30%, our study aims to analyse both short- and long-term outcomes after extra-corporeal membrane oxygenation implant.

Type
Original Article
Copyright
© The Author(s), 2024. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Wu, HP, et al. Predictors of extracorporeal membrane oxygenation support for children with acute myocarditis. Biomed Res Int 2017; 2017: 18.Google ScholarPubMed
Rajagopal, SK, et al. Extracorporeal membrane oxygenation for the support of infants, children, and young adults with acute myocarditis: a review of the extracorporeal life support organization registry. Crit Care Med 2010; 38: 382387.CrossRefGoogle Scholar
Roeleveld, PP, Mendonca, M. Neonatal cardiac ECMO in 2019 and beyond. Front Pediatr 2019; 7: 327.CrossRefGoogle Scholar
Jung, SY, et al. Extracorporeal life support can be a first-line treatment in children with acute fulminant myocarditis. Interact Cardiovasc Thorac Surg 2016; 23: 247252.CrossRefGoogle ScholarPubMed
Lee, EY, et al. Clinical features and short-term outcomes of pediatric acute fulminant myocarditis in a single center. Korean J Pediatr 2014; 57: 489495.CrossRefGoogle ScholarPubMed
Truby, LK, et al. Incidence and implications of left ventricular distention during venoarterial extracorporeal membrane oxygenation support. ASAIO J 2017; 63: 257265.CrossRefGoogle ScholarPubMed
Kotani, Y, et al. Left atrial decompression during venoarterial extracorporeal membrane oxygenation for left ventricular failure in children: current strategy and clinical outcomes. Artif Organs 2013; 37: 2936.CrossRefGoogle ScholarPubMed
Hetzer, R, et al. Improvement in survival after mechanical circulatory support with pneumatic pulsatile ventricular assist devices in pediatric patients. Ann Thorac Surg 2006; 82: 917925.CrossRefGoogle ScholarPubMed