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The effect of consecutive ejaculation on the sperm parameters in the oligo-astheno-teratozoospermia (OAT) men

Published online by Cambridge University Press:  06 January 2025

Akram Hosseini ,
Zahra Borzouie ,
Parvin Khalili  and
Mahboubeh Vatanparast Open the ORCID record for Mahboubeh Vatanparast [Opens in a new window]
Akram Hosseini
Affiliation:
Associated professor of the Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Clinical Center for Infertility, Shahid Behashti Hospital, Isfahan, Iran
Zahra Borzouie
Affiliation:
Associated professor of the Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Clinical Center for Infertility, Shahid Behashti Hospital, Isfahan, Iran
Parvin Khalili
Affiliation:
Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Epidemiology and Biostatistics Department, School of Public Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Mahboubeh Vatanparast*
Affiliation:
Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Clinical Research Development Unit (CRDU), Moradi Hospital (Moradi Education and Clinical Centre), Rafsanjan University of Medical Sciences, Rafsanjan, Iran
*
Corresponding author: Mahboubeh Vatanparast; Email: [email protected]
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Summary

Recently, the World Health Organization recommendation for abstinence time for semen analysis has been challenged in some studies and many of them have supported the advantages of a second short abstinence ejaculation. More evidence is needed to approve this for clinical use. This study aimed to compare the average routine abstinence time (2–7 days) with the short time (1–2 h) on sperm quality based on functional parameters in a population of oligo-astheno-teratozoospermia (OAT) men. The semen samples were retrieved from 50 men with OAT two times: one standard 2–7 days (long ejaculation) and short duration trimming (1–2 hours later the first ejaculation). All semen parameters as well as sperm DNA integrity were compared between groups. Results showed that mean sperm concentration (10.40 vs. 8.76), total sperm count (28.53 vs. 12.24) and mean semen volume (2.69 vs. 1.40) were higher in the first ejaculation (2–7 days of abstinence), while progressive motility (20.52 vs. 13.32), non-progressive motility (53.46 vs. 48.86), morphology (2.46 vs. 1.46) and viability (83.90 vs. 77.96) were significantly higher in the second ejaculation (P < 0.05). The second sample also showed lower immotile (26.82 vs. 38.02) and DNA fragmentation (19.5 vs. 26.96) (P < 0.05). Taking all data into account, an additional short abstinence period (AP) may be a simple and helpful strategy to obtain better sperm quality in couples with male infertility causes, especially in OAT patients. The recommended current guidelines regarding the AP may need to be revisited in severe male factors.

Keywords

consecutive ejaculatesoligo-astheno-teratozoospermia (OAT)short abstinencesperm DNA fragmentationsperm parameters
Type
Research Article
Information
Zygote , First View , pp. 1 - 7
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Copyright
© The Author(s), 2025. Published by Cambridge University Press

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