Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-23T09:12:26.816Z Has data issue: false hasContentIssue false

Discrimination of the effects on zebrafish reproduction from pollutants in drinking water via female, via male and/or via fecundation water

Published online by Cambridge University Press:  09 October 2015

M. Martínez-Sales*
Affiliation:
Aquaculture and Environmental Research Group (ACUMA), Universidad Politécnica de Valencia, Camino de Vera 14, 46022, Valencia, Spain.
F. García-Ximénez
Affiliation:
Aquaculture and Environmental Research Group (ACUMA), Universidad Politécnica de Valencia, Camino de Vera 14, 46022, Valencia, Spain.
F.J. Espinós
Affiliation:
Aquaculture and Environmental Research Group (ACUMA), Universidad Politécnica de Valencia, Camino de Vera 14, 46022, Valencia, Spain.
*
All correspondence to: M. Martínez-Sales. Aquaculture and Environmental Research Group (ACUMA), Universidad Politécnica de Valencia, Camino de Vera 14, 46022, Valencia, Spain. Tel: +34963879433. E-mail: [email protected]

Summary

The lack of preventive policy legislation and the low removal rate of organic pollutants in conventional potabilization treatments lead to some of them being present in drinking water. The problem arises because some of these substances have detrimental effects on human reproduction health, via females, via males or even both. In this work, we established the zebrafish as a bioindicator of these types of substances with the goal of discriminating the effects through three different pathways: male, female or water where the fertilization took place.

For this purpose, four parameters were analysed: fertility rate, hatching rate and survival and abnormalities rates. So, for each parameter two groups were formed, according to whether adult males or females were reared in bottled spring water (Z) or tap water (B) and if the in vitro fertilization took place in water Z or B.

Results revealed a decline in the fertility and hatching rate in water B, due to a water effect. The most plausible explanation could be the presence of substances which affect the micropyle and chorion. Moreover, a decrease in the fertility rate due to an effect over the female was also observed, but in this case by an alteration of the oocyte quality.

Type
Research Article
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bolong, N., Ismail, A.F., Salim, M.R. & Matsuura, T. (2009). A review of the effects of emerging contaminants in wastewater and options for their removal. Desalination 239, 229–46.Google Scholar
Brand, M., Granato, M. & Nüslein-Volhard, C. (2002). Keeping and raising zebrafish. In Zebrafish: A Practical Approach (eds Nüslein-Volhard, C. & Dahm, R.), pp. 733. Oxford, UK: Oxford University Press.Google Scholar
Braw-Tal, R. (2010). Endocrine disruptors and timing of human exposure. Pediatr. Endocrinol. Rev. 8, 41–6.Google Scholar
Galus, M., Kirischian, N., Higgins, S., Purdy, J., Chow, J., Rangaranjan, S., Li, H., Metcalfe, C. & Wilson, J.Y. (2013). Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish. Aquat. Toxicol. 132–133, 200–11.Google Scholar
Galus, M., Rangarajan, S., Lai, A., Shaya, L., Balshine, S. & Wilson, J.Y. (2014). Effects of chronic, parental pharmaceutical exposure on zebrafish (Danio rerio) offspring. Aquat. Toxicol. 151, 124–34.Google Scholar
Khetan, S.K. & Collins, T.J. (2007). Human pharmaceuticals in the aquatic environment: a challenge to green chemistry. Chem. Rev. 107, 2319–64.CrossRefGoogle ScholarPubMed
Martínez-Sales, M., García-Ximénez, F. & Espinós, F.J. (2014). Zebrafish (Danio rerio) as a possible bioindicator of epigenetic factors present in drinking water that may affect reproductive function: is chorion an issue? Zygote 23, 447–52.Google Scholar
Martínez-Sales, M., García-Ximénez, F. & Espinós, F.J. (2015). Zebrafish as a possible bioindicator of organic pollutants with effects on reproduction in drinking waters. J. Environ. Sci. 33, 254–60.Google Scholar
Matthews, M., Trevarrow, B. & Matthews, J. (2002). A virtual tour of the Guide for zebrafish users. Lab. Anim. 31, 3440.Google Scholar
Powers, C.M., Yen, J., Linney, E.A., Seidler, F.J. & Slotkin, T.A. (2010). Silver exposure in developing zebrafish (Danio rerio): Persistent effects on larval behavior and survival. Neurotoxicol. Teratol. 32, 391–7.Google Scholar
Richardson, S.D. & Ternes, T.A. (2011). Water analysis: emerging contaminants and current issues. Anal Chem. 83, 4614–48.Google Scholar
Rodil, R., Quintana, J.B., Concha-Graña, E., López-Mahía, P., Muniategui-Lorenzo, S. & Prada-Rodríguez, D. (2012). Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain). Chemosphere 86, 1040–9.Google Scholar
Santos, E.M., Paull, G.C., Van Look, K.J., Workman, V.L., Holt, W.V., Van Aerle, R., Kile, P. & Tyler, C.R. (2007). Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio). Aquat. Toxicol. 83, 134–42.Google Scholar
Schriks, M., Heringa, M.B., van der Kooi, M.M., de Voogt, P. & van Wezel, A.P. (2010). Toxicological relevance of emerging contaminants for drinking water quality. Water Res. 44, 461–76.Google Scholar
Sharpe, R.M. & Irvine, D.S. (2004). How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health? Brit. Med. J. 328, 447–51.Google Scholar
Shi, X., Du, Y., Lam, P., Wu, R. & Zhou, B. (2008). Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicol. Appl. Pharmacol. 230, 2332.Google Scholar
Simão, M., Cardona-Costa, J., Pérez Camps, M. & García-Ximénez, F. (2010). Ultraviolet radiation dose to be applied in recipient zebrafish embryos for germ-line chimaerism is strain dependent. Reprod. Domest. Anim. 45, 1098–103.Google Scholar
Silva, E., Rajapakse, N. & Kortenkamp, A. (2002). Something from “nothing”—eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ Sci Technol. 36, 1751–6.CrossRefGoogle ScholarPubMed
Toft, G., Rignell-Hydbom, A., Tyrkiel, E., Shvets, M., Giwercman, A., Lindh, C.H., Pedersen, H.S., Ludwicki, J.K., Lesovoy, v., Hagmar, L., Spanó, M., Manicardi, G.C., Bonefeld-Jorgensen, E.C., Thulstrup, A.M. & Bonde, J.P. (2006). Semen quality and exposure to persistent organochlorine pollutants. Epidemiology 17, 450–8.Google Scholar
Vested, A., Giwercman, A., Bonde, J.P. & Toft, G. (2014). Persistent organic pollutants and male reproductive health. Asian J. Androl. 16, 7180.CrossRefGoogle ScholarPubMed
Westerfield, M. (1995). The Zebrafish Book. Eugene, Oregon, USA: University of Oregon Press.Google Scholar
Westerfield, M. (2007). The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio), 5th edn. Eugene, Oregon, USA: University of Oregon Press.Google Scholar
Zhu, X., Zhu, L., Duan, Z., Qi, R., Li, Y. & Lang, Y. (2008). Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to zebrafish (Danio rerio) early developmental stage. J. Environ. Sci. Heal. A 43, 278–84.CrossRefGoogle ScholarPubMed