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Delamination and tyrosine phosphorylation of SUp62 during early embryogenesis of sea urchin

Published online by Cambridge University Press:  16 July 2018

Hideki Katow
Hideki Katow*
Affiliation:
Marine Biological Station, Graduate School of Science, University of Tohoku, Aomori 039-3501, Japan
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Extract

The ingression of primary mesenchyme cells (PMCs) in the sea urchin embryo is initiated with local degradation of the basal lamina at the vegetal plate epithelium (e.g. Katow & Solursh, 1980). The ingressed PMCs encounter pamlin, a cell adhesion protein in the basal lamina (Katow, 1995), which guides PMC migration to a particular embryonic region to form a ring pattern (Katow & Komazaki, 1996; Katow et al, 2000). Thus extracellular matrix (ECM) provides a necessary guidance cue to the migratory cells, and this implicates the occurrence of intracellular signalling to promote not only cell locomotion but also orientation for the migration. Using embryos of the sea urchin, Hemicentrotus pulcherrimus, I report the temporal expression of P35, a PMC surface protein, during the very early stages of PMC ingression that is downregulated with SUp62 protein in the cytoplasm, and tyrosine phosphorylation of SUp62 as a consequence of PMCs encountering pamlin in light of ECM/cell signal transduction.

Type
Special Lecture for Citizens
Information
Zygote , Volume 8 , supplement S1: Proceedings of the International Symposium on Fertilization and Development of Sea Urchin and Marine Invertebrates , December 1999 , pp. S39 - S40
Copyright
Copyright © Cambridge University Press 1999

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References

Katow, H. & Solursh, M. (1980). J. Exp. Zool. 213, 231–46.Google Scholar
Katow, H. (1995). Exp. Cell Res. 218, 469–78.Google Scholar
Katow, H. & Komazaki, S. (1996). Rouxs Arch. Dev. Biol. 205, 371–81.Google Scholar
Katow, H., Yamamoto, Y. & Sofuku, S. (1997). Dev. Growth Differ. 39, 207–19.Google Scholar
Katow, H., Nakajima, Y. & Uemura, I. (2000). Dev. Growth Differ. 42, in press.Google Scholar
Miyatake, M., Hatakeyama, K. & Katow, H. (1998). Proceedings of the 31st Annual Meeting of the Japanese Society of Developmental Biologists.Google Scholar