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Cumulus expansion initiates physical and developmental autonomy of the oocyte

Published online by Cambridge University Press:  26 September 2008

William J. Larsen ,
Lin Chen ,
Robert Powers ,
Hong Zhang ,
Paul T. Russell ,
Carolyn Chambers ,
Karla Hess  and
Robert Flick
William J. Larsen*
Affiliation:
Department of Developmental Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA. Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
Lin Chen
Affiliation:
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
Robert Powers
Affiliation:
Department of Developmental Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
Hong Zhang
Affiliation:
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
Paul T. Russell
Affiliation:
Center for Reproduction Studies, The Christ Hospital, Cincinnati, OH 45219, USA.
Carolyn Chambers
Affiliation:
Department of Biology, Xavier University, Cincinnati, OH 45267, USA.
Karla Hess
Affiliation:
Department of Developmental Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
Robert Flick
Affiliation:
Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Ohio, USA.
*
William J. Larsen, Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati, College of MedicinePO Box 670521, Cincinnati, OH 45267-0521, USA. Telephone: +1(513)558-6788 Fax: +1(513)558-4454.
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Extract

As meiosis is initiated and the oogonium is transformed into a primary oocyte, the female germ cell becomes intimately invested by a single squamous layer of sex cord epithelium. As the follicle cell population expands during the initial stages of the ovarian cycle, oocyte and follicle cells become increasingly connected to one another by one of the most extensive populations of gap junctions documented in any epithelium (reviewed in Larsen & Wert, 1988).

Type
Article
Information
Zygote , Volume 4 , Issue 4 , November 1996 , pp. 335 - 341
Copyright
Copyright © Cambridge University Press 1996

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References

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