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Use of mannan oligosaccharide in broiler diets: an overview of underlying mechanisms

Published online by Cambridge University Press:  17 October 2017

M.F.A. CHACHER ,
Z. KAMRAN ,
U. AHSAN ,
S. AHMAD ,
K.C. KOUTOULIS ,
H.G. QUTAB UD DIN  and
Ö. CENGIZ
M.F.A. CHACHER*
Affiliation:
Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Ataturk University, 25240 Erzurum, Turkey
Z. KAMRAN
Affiliation:
University College of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
U. AHSAN
Affiliation:
Department of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Adnan Menderes University, Aydın 09016, Turkey
S. AHMAD
Affiliation:
Training Operation Department, Al-Watania Poultry Institute of Technology, Al-Bukayriyah, Saudi Arabia
K.C. KOUTOULIS
Affiliation:
Department of Avian Medicine, Faculty of Veterinary Science, School of Health Sciences, University of Thessaly, Karditsa, Greece 4310
H.G. QUTAB UD DIN
Affiliation:
Department of Animal Science, Faculty of Agriculture, Ataturk University, 25240-Erzurum, Turkey
Ö. CENGIZ
Affiliation:
Department of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Adnan Menderes University, Aydın 09016, Turkey
*
Corresponding author: [email protected]
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Abstract

Antibiotic resistance has led poultry nutritionists to find alternatives for antibacterial growth promoters in broilers. Among these substitutes, one is mannan oligosaccharides (MOS), a yeast cell wall derived prebiotic. MOS decreases the load of pathogenic bacteria through 1) binding bacterial type-1 fimbriae 2) increasing goblet cells which produce bactericidal mucin and 3) providing favourable environment for the growth of beneficial bacteria leading to competitive exclusion. Balance between pathogenic and beneficial bacteria causes increase in villus length and decrease in crypt depth which are biomarkers for gut morphological improvement. As structure is equal to function, improvement in intestinal morphology increases activity of digestive enzymes and ultimately improves digestion. Besides these, immunomodulatory effect of MOS activates macrophages of gut associated lymphoid tissues resulting in improvement in cellular, humoral and cutaneous immunity. MOS also increases production of butyric acid and decrease pH of intestine in broilers. Though these combined mechanisms, MOS improves growth rate and performance of broilers.

Keywords

mannan oligosaccharidesintestinal microfloramorphologyimmunityperformance
Type
Reviews
Information
World's Poultry Science Journal , Volume 73 , Issue 4 , December 2017 , pp. 831 - 844
Copyright
Copyright © World's Poultry Science Association 2017 

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