Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-20T02:22:10.617Z Has data issue: false hasContentIssue false
  • English
  • Français

Use of liquorice (Glycyrrhiza glabra) in poultry nutrition: Global impacts on performance, carcass and meat quality

Published online by Cambridge University Press:  01 April 2019

M. ALAGAWANY ,
S.S. ELNESR  and
M.R. FARAG
M. ALAGAWANY*
Affiliation:
Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt
S.S. ELNESR
Affiliation:
Department of Poultry Production, Faculty of Agriculture, Fayoum University, 63514 Fayoum, Egypt
M.R. FARAG
Affiliation:
Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt
*
Corresponding author: [email protected], [email protected]
Get access

Abstract

Supplementation of poultry diets with medicinal plants containing bioactive molecules have shown promising results in promoting growth performance, enhancing feed efficiency, and improving carcass traits and meat quality. There are many studies using herbal plants and their derivatives involving liquorice (Glycyrrhiza glabra), while studies using only liquorice are very limited. Liquorice contains bioactive components such as glycyrrhizin and flavonoids, and has been linked to many pharmacological effects like immunomodulatory, anti-oxidant, antiviral and anti-inflammatory activity. Supplementation of liquorice in poultry diets had beneficial impacts on growth and performance by improving organ development. In addition, there are appetite and digestion stimulating factors in liquorice. Dietary liquorice supplementation at level of 2.5 g/kg showed the best results in broiler chicken, and demonstrated it can be safely used in poultry diets. Addition of liquorice in diets up to 0.5% inclusion before sexual maturity enhanced performance of laying hens. Furthermore, broilers receiving drinking water containing 450 mg/l liquorice under heat stress significantly improved feed conversion and economic efficiency. Abdominal fat in broiler chickens was decreased when liquorice was included at 2 g/kg in feed or 0.3 g/l in drinking water. Broiler chickens with access to drinking water containing 450 mg/l of liquorice increased the dressing percentage, with or without giblets. Carcass organoleptics were improved in birds receiving drinking water with liquorice at levels of either 1, 2 and 4 mg/ kg body weight. This review describes the chemical composition, health benefits and beneficial applications of the liquorice herb and its effect on growth and productive performance, carcasses and meat quality, which will be useful for researchers, physiologists, nutritionists, veterinarians, scientists, pharmacists, pharmaceutical industries, and poultry breeders.

Keywords

liquoriceperformancecarcassesmeatpoultry
Type
Review
Information
World's Poultry Science Journal , Volume 75 , Issue 2 , June 2019 , pp. 293 - 304
Copyright
Copyright © World's Poultry Science Association 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ABDELNOUR, S., ALAGAWANY, M., EL-HACK, M.E.A., SHEIHA, A.M., SAADELDIN, I.M. and SWELUM, A.A. (2018) Growth, carcass traits, blood hematology, serum metabolites, immunity, and oxidative indices of growing rabbits fed diets supplemented with red or black pepper oils. Animals 8: 168.Google Scholar
ALAGAWANY, M., ABD EL-HACK, M.E., FARAG, M.R., ELNESR, S.S., EL-KHOLY, M.S., SAADELDIN, I.M. and SWELUM, A.A. (2018a) Dietary supplementation of Yucca schidigera extract enhances productive and reproductive performances, blood profile, immune function, and antioxidant status in laying Japanese quails exposed to lead in the diet. Poultry Science 97: 3126-3137.Google Scholar
ALAGAWANY, M., ABD EL-HACK, M.E., FARAG, M.R., SHAHEEN, H.M., ABDEL-LATIF, M.A, NORELDIN, A.E. and PATRA, A.K. (2018b) The usefulness of oregano and its derivatives in poultry nutrition. World's Poultry Science Journal 74: 463-474.Google Scholar
AL-DARAJI, H.J. (2012) Influence of drinking water supplementation with licorice extract on certain blood traits of broiler chickens during heat stress. Report and Opinion 4: 56-60.Google Scholar
AL-DARAJI, H.J. (2013) Effects of liquorice extract, probiotic, potassium chloride and sodium bicarbonate on productive performance of broiler chickens exposed to heat stress. International Journal of Advanced Research 1: 172-180.Google Scholar
AL-ZUHAIRY, M.A. and HASHIM, M.E. (2014) Influence of different levels of licorice (Glycyrrhiza glabra Inn.) and garlic (Allium sativum) mixture powders supplemented diet on broiler Productive traits. The Iraqi Journal of Veterinary Medicine 39: 9-14.Google Scholar
AOKI, F., HONDA, S., KISHIDA, H., KITANO, M., ARAI, N., TANAKA, H., YOKATO, S. and NAKAGAWA, K. (2007) Suppression by licorice flavonoids of abdominal fat accumulation and body weight gain in high-fat diet-induced obese C57BL/6J mice. Bioscience, Biotechnology, and Biochemistry 71: 206-214.Google Scholar
ARMANINI, D., PALO, C.B., MATTARELLO, M.J., SPINELLA, P., ZACCARIA, M., ERMOLAO, A., PALERMO, M., FIORE, C., SARTORATO, P., FRANCINI PESENTI, F. and KARBOWIAK, I. (2003) Effect of licorice on the reduction of body fat mass in healthy subjects. Journal of Endocrinological Investigation 26: 646-650.Google Scholar
ASL, M.N. and HOSSEINZADEH, H. (2008) Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytotherapy Research 22: 709-724.Google Scholar
AWADEIN, N.B., EID, Y.Z. and EL-GHANY, F.A. (2010) Effect of dietary supplementation with phytoestrogens sources before sexual maturity on productive performance of Mandarah hens. Egyptian Poultry Science Journal 30: 829-846‏.Google Scholar
BADR, S.E.A., SAKR, D.M., MAHFOUZ, S.A. and ABDELFATTAH, M.S. (2013) Liquorice (Glycyrrhiza glabra L.): Chemical Composition and Biological Impacts. Research Journal of Pharmaceutical, Biological and Chemical Sciences 4: 606-621.Google Scholar
BERNARDI, M., D'LNTINO, P.E. and TREVISANI, F. (1994) Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. Life Science 55: 863-872.Google Scholar
BIONDI, D.M., ROCCO, C. and RUBERTO, G. (2005) Dihydrostilbene derivatives from Glycyrrhiza glabraleaves. Journal of Natural Products 68: 1099-1102.Google Scholar
CASTANON, J. (2007) History of the use of antibiotics as growth promoters in European poultry feeds. Journal Poultry Science 86: 2466-2471.Google Scholar
CORONADO, S.A., TROUT, G.R., DUNSEA, F.R. and SHAH, N.P. (2002) Antioxidant effects of rosemary extract and whey powder on the oxidative stability of wiener sausages during 10 months frozen storage. Meat Science 62: 217-224.Google Scholar
DHAMA, K., KARTHIK, K., KHANDIA, R., MUNJAL, A., TIWARI, R., RANA, R., KHURANA, S.K., ULLAH, S., KHAN, R.U., ALAGAWANY, M., FARAG, M.R., DADAR, M. and JOSHI, S.K. (2018) Medicinal and therapeutic potential of herbs and plant metabolites / extracts countering viral pathogens - current knowledge and future prospects. Current Drug Metabolism 19: 236-263.Google Scholar
EFFA (2001) Ammonium glycyrrhizinate. European Flavour and Fragrance Association (EFFA), Submission to Scoop Working Group on Chemically Defined Flavouring Substances, Document No. SCOOP/FLAV/8.4, SCF Document No. SCF/CS/ADD/MSAD/203.Google Scholar
ERDOĞAN, Z., ERDOĞAN, S., DOĞANLAR, Z.B., DOĞANLAR, O. and CANOĞULLARI, S. (2016) Glycyrrhiza glabra protects the liver hepatocytes from the volatile organic compounds. Toxicology Letters 258: S180.Google Scholar
FENWICK, G.R., LUTOMSKI, J. and NIEMAN, C. (1990) Liquorice, Glycyrrhiza glabra L.-Composition, uses and analysis. Food Chemistry 38: 119-143.Google Scholar
FIORE, C., EISENHUT, M., KRAUSSE, R., RAGAZZI, E., PELLATI, D., ARMANINI, D. and BIELENBERG, J. (2008) Antiviral effects of Glycyrrhiza species. Phytotherapy Research 22: 141-148.Google Scholar
FRANKIČ, T., VOLJČ, M., SALOBIR, J. and REZAR, V. (2009) Use of herbs and spices and their extracts in animal nutrition. Acta Agriculturae Slovenica 94: 95-102.Google Scholar
HERNÁNDEZ, F., MADRID, J., GARCIA, V., ORENGO, J. and MEGIAS, M.D. (2004) Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poultry Science 83: 169-174.Google Scholar
HOSSEINI, S.A., GODARZI, M., ZAREI, A., MEIMANDIPOOR, A. and SAFAEI, A.R. (2011) Choosing a ground herbal plant for antibiotic growth promoters substitution in broiler Based on multi-criteria Decision Analysis. Researches of the first international conference (Babylon and Razi Universities).Google Scholar
HUSAIN, A., AHMAD, A., MUJEEB, M., KHAN, S.A., ALGHAMDI, A.G. and ANWAR, F. (2015) Quantitative analysis of total phenolic, flavonoid contents and HPTLC fingerprinting for standardization of Glycyrrhiza glabra linn roots. Herbal Medicine 1: 1-9.Google Scholar
KAGEYAMA, Y., SUZUKI, H. and SARUTA, T. (1994) Role of glucocorticoid in the development of glycyrrhizin-induced hypertension. Clinical and Experimental Hypertension 16: 761-778.Google Scholar
KALANTAR, M., HOSSEINI, S.M., YANG, L., RAZA, S.H.A., GUI, L., REZAIE, M., KHOJASTEKEY, M., WEI, D., KHAN, R., YASAR, S., SYED, S.F., KACHIWAL, A.B., ELKHAIREY, M., LEI, Q., KALERI, R.R. and ABD EL-AZIZ, A.H. (2017) Performance, immune, and carcass characteristics of broiler chickens as affected by thyme and licorice or enzyme supplemented diets. Open Journal of Animal Sciences 7: 105-109.Google Scholar
KARIMI, B., RAHIMI, S.H. and KARIMI TORSHIZI, M.A. (2015) Comparing the effects of six herbal extracts and antibiotic virginiamycin on immune response and serum lipids in broiler chickens. Iranian Journal of Medicinal and Aromatic Plants 31: 177-184.Google Scholar
KATO, H., KANEKA, M. and YANO, S. (1995) 3 - Monoglucuronyl - glycyrrhetinic acid a major metabolite that causes licorice - induced pseudoaldosteronism. Journal of Clinical Endocrinology and Metabolism 80: 1929-1933.Google Scholar
KHAMISABADI, H., POURHESABI, G., CHAHARAEIN, B. and NASERI, H.R. (2015) Comparison of the effects of licorice extract (Glycyrrhiza glabra) and lincomycine on abdominal fat biochemical blood parameter and immunity of broiler chickens. Animal Science Journal(Pajouhesh and Sazandegi) 105: 229-244.Google Scholar
LASHIN, I.A., IBORAHEM, I., OLA, F.A., TALKHAN, F. and MOHAMED, F. (2017) Influence of licorice extract on heat stress in broiler chickens. Animal Health Research Journal 5: 40-46.Google Scholar
LI, J.R., WANG, Y.Q. and DENG, Z.Z. (2005) Two new compounds from Glycyrrhiza glabra. Journal of Asian Natural Products Research 7: 677-680.Google Scholar
MAO, S.J., HOU, S.X., HE, R., ZHANG, L.K., WEI, D.P., BI, U.Q. and JIN, H. (2005) Uptake of albumin nanoparticle surface modified with glycyrrhizin by primary cultured rat hepatocytes. World Journal of Gastroenterology 11: 3075-3079.Google Scholar
MICHAELIS, M., GEILER, J., NACZK, P., SITHISARN, P., LEUTZ, A., DOERR, H.W. and CINATL, J. (Jr) (2011) Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. PLoS ONE 6: 10.1371/journal.pone.0019705.Google Scholar
MORADI, N., GHAZI, S., AMJADIAN, T., KHAMISABADI, H. and HABIBIAN, M. (2014) Performance and some immunological parameter responses of broiler chickens to licorice (Glycyrrhiza glabra) extract administration in the drinking water. Annual Research & Review in Biology 4: 675-683.Google Scholar
MUKHOPADHYAY, M. and PANJA, P. (2008) A novel process for extraction of natural sweetener from licorice (Glycyrrhiza glabra) roots. Separation and Purification Technology 63: 539-545.Google Scholar
MYANDOAB, M.P. and MANSOUB, N.H. (2012) Comparative effect of liquorice root extract medicinal plants and probiotic in diets on performance, carcass traits and serum composition of Japanese quails. Global Veterinaria 8: 39-42.Google Scholar
NAKAGAWA, K., KISHIDA, H., ARAI, N., NISHIYAMA, T. and MAE, T. (2004) Liquorice flavonoids suppress abdominal fat accumulation and increase in blood glucose level in obese diabetic KK-A(y) mice. Biological and Pharmaceutical Bulletin 27: 1775-1778.Google Scholar
NASER, M., SHAHAB, G. and MAHMOOD, H. (2017) Drinking water supplementation of licorice (Glycyrrhiza glabra L. root) extract as an alternative to in-feed antibiotic growth promoter in broiler chickens. GSC Biological and Pharmaceutical Sciences 1: 20-28.Google Scholar
OCAMPO, C.L., GÓMEZ-VERDUZCO, G., TAPIA-PEREZ, G., GUTIERREZ, O.L. and SUMANO, L.H. (2016) Effects of glycyrrhizic acid on productive and immune parameters of broilers. Brazilian Journal of Poultry Science 18: 435-442.Google Scholar
OHNO, H., ARAHO, D., UESAWA, Y., KAGAYA, H., ISHIHARA, M., SAKAGAMI, H. and YAMAMOTO, M. (2013) Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure. Anticancer Research 33: 3061-3068.Google Scholar
PARVAIZ, M., HUSSAIN, K., KHALID, S., HUSSNAIN, N., IRAM, N., HUSSAIN, Z.H. and ALI, M.H. (2014) A review: Medicinal importance of glycyrrhizaglabra L. (Fabaceace Family). Global Journal of Pharmacology 8:8-13.Google Scholar
QUIRÓS-SAUCEDA, A.E., OVANDO-MARTÍNEZ, M., VELDERRAIN-RODRÍGUEZ, G.R., GONZÁLEZ-AGUILAR, G.A. and AYALA ZAVALA, J.F. (2016) Liquorice (Glycyrrhiza glabra Linn.) oils, in: PREEDY, V.R. (Ed) Essential Oils in Food Preservation, Flavor and Safety, Chapter 60, First Edition 2016, pp. 523-530.Google Scholar
RAČKOVÁ, L., JANČINOVÁ, V., PETRÍKOVÁ, M., DRÁBIKOVÁ, K., NOSÁL, R., ŠTEFEK, M., KOŠŤÁLOVÁ, D., PRÓNAYOVÁ, N. and KOVÁČOVÁ, M. (2007) Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Natural Product Research 21: 1234-1241.Google Scholar
REZAEI, M., KALANTAR, M. and NASR, J. (2014) Thymus vulgaris L., Glycyrrhiza glabra and combo enzyme in corn or barley-basal diets in broiler chickens. The International Journal of Plant, Animal and Environmental Sciences 4: 418-423.Google Scholar
SAEED, M., ARAIN, M.A., NAVEED, M., ALAGAWANY, M., ABD EL-HACK, M.E., BHUTTO, Z.A., BEDNARCZYK, M., KAKAR, M.U., ABDEL-LATIF, M. and CHAO, S. (2018) Yucca schidigera can mitigate ammonia emissions from manure and promote poultry health and production. Environmental Science and Pollution Research 25: 35027-35033.Google Scholar
SALARY, J., KALANTAR, M., SAHEBI ALA, M., RANJBAR, K. and HEMATI MATIN, H.R. (2014) Drinking water supplementation of licorice and Aloe vera extracts in broiler chickens. Journal of Animal Science 3: 41-48.Google Scholar
SEDGHI, M., GOLIAN, A., KERMANSHAHI, H. and AHMADI, H. (2010) Effect of dietary supplementation of licorice extract and a prebiotic on performance and blood metabolites of broilers. South African Journal of Animal Science 40(4): http://dx.doi.org/10.4314/sajas.v40i4.65259.Google Scholar
SHABANI, L., EHSANPOUR, A.A., ASGHARI, G. and EMAMI, J. (2009) Glycyrrhizin production by in vitro cultured Glycyrrhiza glabra elicited by Methyl Jasmonate and salicylic acid. Russian Journal of Plant Physiology 56: 621-626.Google Scholar
SHALABY, M.A., IBRAHIM, H.S., MAHMOUD, E.M. and MAHMOUD, A.F. (2004) Some effects of Glycyrrhiza glabra (liquorice) roots extract on male rats. Egyptian Journal of Natural Toxins 1: 83-94.Google Scholar
SHEBL, R.I., AMIN, M.A., EMAD-ELDIN, A., BIN DAJEM, S.M, MOSTAFA, A.S., IBRAHIM, E.H. and MOHAMED, A.F. (2012) Antiviral activity of liquorice powder extract against varicella zoster virus isolated from Egyptian patients. Chang Gung Medicine Journal 35: 231-239.Google Scholar
SHEN, H., ZENG, G., SUN, B., CAI, X., BI, L. and TANG, G. (2015) A polysaccharide from Glycyrrhiza inflata Liquorice inhibits proliferation of human oral cancer cells by inducing apoptosis via mitochondrial pathway. International Society for Oncodevelopmental Biology and Medicine 36: 4825-4831.Google Scholar
SHIBATA, S.A. (2000) A drug over the millennia: pharmacognosy, chemistry, and pharmacology of licorice. Yakugaku Zasshi 120: 849-862.Google Scholar
SHU, Z., HE, W., SHAHEN, M., GUO, Z., SHU, J., WU, T., BIAN, X., SHAR, A.H., FARAG, M.R., ALAGAWANY, M. and LIU, C. (2018) Clarifying the mechanism of Sinisan formula for treatment of chronic hepatitis by systems pharmacology method. Biomedicine & Pharmacotherapy 100: 532-550.Google Scholar
SOHAIL, M., RAKHA, A., BUTT, M.S. and ASGHAR, M. (2018) Investigating the antioxidant potential of licorice extracts obtained through different extraction modes. Journal of Food Biochemistry 42: e12466.Google Scholar
SUCHITRA, G. and SHAKUNTHALA, V. (2014) Effect of glycyrrhiza glabra root extract on behaviour and fitness of drosophila melanogaster and vestigial wing mutant. International Journal of Current Microbiology and Applied Sciences 3: 1047-1054.Google Scholar
TAMIR, S., EIZENBERG, M. and SOMJEN, D. (2001) Estrogen like activity of glabrene and other constituents isolated from licorice root. The Journal of Steroid Biochemistry and Molecular Biology 78: 291-298.Google Scholar
TOMINAGA, Y., TATSUMASA, M., MITSUAKI, K., YOSHIRO, S., HIDEYUKI, I. and NAKAGAWA, N. (2006) Liquorice flavonoid oil effect body weight loss by reduction of body fat mass in overweight subject. Journal of Health Science 52: 672-683.Google Scholar
VAYA, J., BELINKY, P.A. and AVIRAM, M. (1997) Antioxidant constituents from licorice roots isolation, structure elucidation and antioxidative capacity toward LDL oxidation. Free Radical Biology & Medicine 23: 302-313.Google Scholar
VAYA, J., BELINKY, P.A. and AVIRAM, M. (1997) Antioxidant constituents from licorice roots: isolation, structure elucidation and antioxidative capacity toward LDL oxidation. Free Radical Biology and Medicine 23: 302-313.Google Scholar
VELMURUGAN, N., KALPANA, D., CHO, J.Y. and LEE, Y.S. (2018) Chemical composition and antioxidant capacity of the aqueous extract of Phellodendron amurense. Journal of Forestry Research 29: 1041-1048.Google Scholar
VLAISAVLJEVIĆ, S., ŠIBUL, F., IZABELLA, S., ZUPKOB, I., OCSOVSZKI, I. and JOVANOVIĆ-ŠANTA, S. (2018) Chemical composition, antioxidant and anticancer activity of licorice from Fruska Gora locality. Industrial Crops & Products 112: 217-224.Google Scholar
WANG, L.R., ZHANG, H.T., LIU, B.G., DONG, Y.J., WANG, C.M., WANG, Y.R., SHI, M. and ZHANG, Y.L. (2004) Extraction of Glycyrrhizin polysaccharide and its effects on growth performance of broilers. Chinese Feeds Industry 25: 44-45.Google Scholar
WINDISCH, W., SCHEDLE, K., PLITZNER, C. and KROIS-MAYR, A. (2008) Use of phytogenic products as feed additives for swine and poultry. Journal of Animal Science 86: 140-148.Google Scholar
ZHANG, X., ZHAO, L., CAO, F., AHMAD, H., WANG, G. and WANG, T. (2013) Effects of feeding fermented Ginkgo biloba leaves on small intestinal morphology, absorption, and immunomodulation of early lipopolysaccharide-challenged chicks. Poultry Science 92: 119-130.Google Scholar