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Significance of phytic acid and supplemental phytase in chicken nutrition: a review

Published online by Cambridge University Press:  12 November 2008

P.K. SINGH
P.K. SINGH*
Affiliation:
Department of Animal Nutrition, Bihar Veterinary College, Patna-800014, India
*
Corresponding author: [email protected]
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Abstract

Phytic acid is an anti-nutritional constituent of plant derived feeds. As a reactive anion, it forms a wide variety of insoluble salts with minerals including phosphorus, calcium, zinc, magnesium and copper. Phytic acid is also known to form complexes with protein and proteolytic enzymes (pepsin and trypsin). Because of the lack of endogenous phytase enzymes that hydrolyze phytic acid; phosphorus, calcium, protein and other phytic acid bound nutrients are less available to poultry. Commercially-available microbial phytase has great nutritional significance and ecological importance. Poultry diets supplemented with microbial phytase result in improved growth performance and increased digestibility and availability of phytate bound phosphorous, calcium, zinc and copper. Microbial phytase supplementation has also been shown to increase ileal digestibility of crude protein and amino acids. The efficacy of supplemental microbial phytase depends on its rate of inclusion, dietary calcium and phosphorus ratio, vitamin D3, nature of diet, age and genotype of birds. Thus, microbial phytase can be used to exploit the inherent nutritional potential of feedstuffs for more economic and environmentally-friendly poultry production.

Keywords

phytic acidphytasephosphorusproteindigestibilitypollutionpoultry
Type
Review Article
Information
World's Poultry Science Journal , Volume 64 , Issue 4 , December 2008 , pp. 553 - 580
Copyright
Copyright © World's Poultry Science Association 2008

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References

AFSHARMANESH, M. and POURREZA, J. (2005) Effects of calcium, citric acid, ascorbic acid, vitamin D on the efficacy of phytase in broiler starters. International Journal of Poultry Science 4(6): 418-424Google Scholar
AHMAD, T., RASSOL, S., SARWAR, M., HAQ, A. and HASAN, Z. (2000) Effect of microbial phytase produced from a fungus Aspergillus niger on bioavailability of phosphorus and calcium in broiler chicken. Animal Feed Science and Technology 83: 103-114CrossRefGoogle Scholar
AKYUREK, H., SENKOYLU, N. and OZDUVEN, M.L. (2005) Effect of microbial phytase on growth performance and nutrient digestibility in broiler. Pakistan Journal of Nutrition 4(1):22-26Google Scholar
ANDERSON, P.A. (1985) Interaction between protein and constituents that affect protein quality. In: FINLEY, J.W. AND HOPKINS, D.T. (Eds) Digestibility and Amino Acid Availability in Cereals and Oilseeds. pp 31-45, American Association of Cereal Chemists, Inc., St Paul, MN.Google Scholar
ANGEL, R., SAVLOR, W.W., MITCHELL, A.D., POWERS, W. and APPLEGATE, T.J. (2006) Effect of dietary phosphorus, phytase and 25-hydroxycholecalciferol on broiler chicken bone mineralization, litter phosphorus, and processing yields. Poultry Science 85 (7):1200-1211.CrossRefGoogle ScholarPubMed
ASADA, K., TANAKA, K. and KASAI, Z. (1969) Formation of phytic acid in cereal grain. Annals of New York Academy Science 165: 801-806.Google Scholar
AOYAGI, S. and BAKER, D. (1995) Effect of microbial phytase and 1, 25-dihydroxycholecalciferol on dietary copper utilization in chicks. Poultry Science 74: 121-126.CrossRefGoogle ScholarPubMed
BALLAM, G.C., NELSON, T.S. and KIRBY, L.K. (1984) Effect of fiber and phytate source and of calcium and phosphorus level on phytate hydrolysis in the chick. Poultry Science 63: 333-338.CrossRefGoogle ScholarPubMed
BARRIER-GILLOT, B., CASADO, P., JONDREVILLE, C. and GATEL, F. (1996) Wheat-phosphorus availability: I- In vitro study: factors affecting endogenous phytasic activity and phytic phosphorous content. Journal of the Science of Food and Agriculture 70: 62-68.3.0.CO;2-M>CrossRefGoogle Scholar
BASSIRI, A. and NAHAPETION, A. (1977) Differences in concentrations and interrelationships of phytate, phosphorus, magnesium, calcium, zinc and iron in wheat varieties grown under dry land and irrigated conditions. Journal of Agriculture and Food Chemistry 24:1118-1122.CrossRefGoogle Scholar
BIEHL, R.R., BAKER, D.H. and DELUCA, H.F. (1995) Hydroxylated cholecalciferol compounds act additively with microbial phytase to improve phosphorus, zinc and manganese in chicks fed soy-based diets. Journal of Nutrition 125: 2407-2416.CrossRefGoogle ScholarPubMed
BIEHL, R.R. and BAKER, D.H. (1997) Microbial phytase improves amino acid utilization in young chicks fed diets based on soyabean meal but not diets based on peanut meal. Poultry Science 76: 355-360.CrossRefGoogle Scholar
BROZ, J., OLDANE, P., PERRIN-VOLTZ, A.H., RYCHEN, G., SCHULZE, J. and NUCHES, C.S. (1994) Effect of supplemental phytase on performance and phosphorus utilization in broiler Chickens fed low phosphorus diet without addition of inorganic phosphorus. British Poultry Science 35: 273-280.CrossRefGoogle Scholar
CABAHUG, S., RAVINDRAN, V., BRYDEN, W.L. and SELLE, P.H. (1999) Response of broilers to microbial phytase supplementation as influenced by dietary phytic acid and non-phytate phosphorus levels. I. Effects on broiler performance and toe ash content. British Poultry Science 40: 660-666.CrossRefGoogle Scholar
CALDWELL, R.A. (1992) Effect of calcium and phytic acid on the activation of trypsinogen and the stability of trypsin. Journal of Agricultural and Food Chemistry 40: 43-46.CrossRefGoogle Scholar
CARLOS, A.B. and EDWARDS, H.M. Jr. (1998) The effects of 1, 25-dihydroxycholecalciferol and phytase on natural phytate phosphorus utilization by laying hens. Poultry Science 77: 850-858.CrossRefGoogle ScholarPubMed
CAWLEY, R.W. and MITCHELL, T.A. (1968) Inhibition of wheat alpha-amylase by bran phytic acid. Journal of the Sciences of Food and Agriculture 19: 106-110.CrossRefGoogle Scholar
CHAMPAGNE, E.T. (1988) Effects of pH on mineral-phytate, protein-mineral-phytate and mineral-fiber interactions. Possible consequences of atrophic gastritis on mineral bioavailability from high fiber foods. Journal of American College of Nutrition 38: 199-215.Google Scholar
CHERYAN, M. (1980) Phytic acid interactions in food systems. CRC Critical Reviews in Food Science and Nutrition 13: 297-302.CrossRefGoogle ScholarPubMed
COOPER, J.R. and GOWING, H.S. (1983) Mammalian small intestine phytase (EC 3.1.3.8). British Journal of Nutrition 50: 673-678.CrossRefGoogle ScholarPubMed
CORTES, C.A., FUENTE, M.B., FERNANDES, T.S., MOJICA, E. and AVILA, M.C. (2007) Evaluation of the presence of a microbial phytase (Peniophora lycii) in sorghum-soyabean phosphorus-deficient meal diets, for broilers on ileal protein, and amino acid digestibility and metabolizable energy. Veterinaria Mexico 38 (1): 21-30.Google Scholar
COSGROVE, D.J. (1966) The chemistry and biochemistry of inositol phosphates. Review of Pure and Applied Chemistry 16: 209-215.Google Scholar
COSGROVE, D.J. (1980) Inositol Phosphates: Their Chemistry, Biochemistry and Physiology. Elsevier Publication Scientific Publishing Co., New York.Google Scholar
COWIESON, A.J. and RAVINDRAN, V. (2007) Effect of phytic acid and microbial phytase on the flow and amino acid composition of endogenous protein at the terminal ileum of growing broiler chickens. British Journal of Nutrition 98 (4): 745-752.CrossRefGoogle ScholarPubMed
DAVIES, N.T. and REID, H. (1979) An evaluation of the phytate, zinc, copper, iron and manganese contents of and zinc availability form soya-based textured-vegetable-protein meat substitutes or meat-extenders. British Journal of Nutrition 41: 579-588.CrossRefGoogle ScholarPubMed
DAVIS, P.N., NORRIS, L.C. and KRATZER, F.H. (1961) Interference of soyabean protein with the utilization of trace minerals. Journal of Nutrition 77: 217-221.CrossRefGoogle Scholar
DE BOLAND, A.R., GAMER, G.B. and O`Dell. B.L., (1975) Identification and properties of phytate in cereal grains and oil seed products. Journal of Agricultural and Food Chemistry 23: 1186-1189.CrossRefGoogle Scholar
DE RHAM, O. and JOST, T. (1979) Phytate-protein interactions in soybean extracts and low-phytate soy protein products Journal of Food Science 44: 596-601.CrossRefGoogle Scholar
DENBOW, D.M., RAVINDRAN, V., KORNEGAY, E.T., YI, Z. and HULET. R.M., (1995) Improving phosphorous availability in soyabean meal for broilers by supplemental phytase. Poultry Science 74: 1831-1842.CrossRefGoogle ScholarPubMed
DESHPANDE, S.S. and CHERYAN, M. (1984) Effects of phytic acid divalent cations, and their interactions on alpha-amylase activity. Journal of Food Science 49: 516-519.CrossRefGoogle Scholar
EASTWOOD, M.A. (1973) Vegetable fiber: Its physical properties. Proceeding of Nutrition Society 32: 137-143.CrossRefGoogle ScholarPubMed
EDWARDS, H.M. Jr. (1966) The effect of protein source in the diet of Zn65 absorption and excretion by chickens. Poultry Science 45: 421-422.CrossRefGoogle Scholar
EDWARDS, H.M. Jr. (1983) Phosphorus. 1. Effect of breed and strain on utilization of sub-optimal levels of phosphorus in the rations. Poultry Science 62: 77-84.CrossRefGoogle Scholar
EDWARDS, D.R and DANIEL, T.C. (1992) Environmental impacts of on-farm poultry waste disposal- a review. Bioresource Technology 41: 9-33.CrossRefGoogle Scholar
EDWARDS, H.M. Jr. and VELTMAN, J.R. Jr. (1983) . The role of calcium and phosphorus in the etiology of tibial dyschondroplasia in young chicks. Journal of Nutrition 113: 1568.CrossRefGoogle ScholarPubMed
EDWARDS, H.M. Jr., PALO, P., SOONCHAERENYING, S. and ELLIOT, M.A. (1989) . Factors influencing the bioavailability of phytate phosphorus to chickens. In: SOUTHGATE, D., JOHNSON, I. & FENWICK, G.R. (Eds) Nutrient availability: Chemical and Biological Aspects, pp. 271-276 (The Royal Society of Chemistry. Cambridge).Google Scholar
EDWARDS, H.M. Jr. (1993) Dietary 1, 25-dihydroxycholecalciferolsupplementaion increases natural phytate phosphorus utilization in chickens. Journal of Nutrition 123: 567-577.CrossRefGoogle ScholarPubMed
EECKHOUT, W. and DE PAEPE, M. (1994) Total phosphorus phytate-phosphorus and phytase activity in plant feed stuffs. Animal Feed Science and Technology 47: 19-29.CrossRefGoogle Scholar
EECKHOUT, W. and DD PAEPE, M. (1996) In vitro and in vivo comparison of microbial and plant phytase. In: COELHO, M.B. & KORNEGAY, E.T. (Eds) Phytase in Animal Nutrition and Waste Management, pp. 237-240 (BASF, New Jersey).Google Scholar
ENGELEN, A.J., VAN DER HEEFT, E.C., RANDSDORP, P.H.G. and SMITH, E.L.C. (1994) Simple and Rapid determination of phytase activity. Journal of the Association of Official Analytical Chemists International 77: 760-764.Google ScholarPubMed
ERDMAN, J.W. Jr. (1979) Oilseed phytate: Nutritional implications. Journal of American Oil Chemists Society 56: 736-741.CrossRefGoogle Scholar
EWING, W.R. (1963) Poultry Nutrition. 5th Ed. The Ray Ewing Company, Passadena, California.Google Scholar
FARRELL, D.J., MARTIN, E. PAEPE, J.J., , BONGARTS, M., SUDAMAN, A. and THOMSON, G. (1993) The beneficial effects of microbial phytase ion diets of broiler chickens and ducklings. Journal of Animal Physiology and Animal Nutrition 69: 278-286.CrossRefGoogle Scholar
GIFFORD, S.R. and CLYDESDALE, F.M. (1990) Interactions among calcium, zinc and phytate with three protein sources. Journal of Food Science 55: 1720-1724.CrossRefGoogle Scholar
GORDON, R.W. and ROLAND, S.R. (1997) Performance of commercial laying hens fed various phosphorus levels with and without supplemental phytase. Poultry Science 76: 1172-1177.CrossRefGoogle ScholarPubMed
HAN, Y.W. (1988) Removal of phytic acid from soyabean and cottonseed meals. Journal of Agricultural and Food Chemistry 36: 1181-1183.CrossRefGoogle Scholar
HEDGE, S.N., ROLLS, B.A., TURVEY, A. and COATES, M.E. (1978) The effects on chicks of dietary fiber from different source: A growth factor in wheat bran. British Journal of Nutrition 40:63-69.Google Scholar
INTERNATIONAL UNION of BIOCHEMISTRY, (1979) Enzyme nomenclature: Recommendations (1978) of the Nomenclature Committee of the International Union of Biochemistry. Academic Press, New York, pp 242-247.Google Scholar
JOHNSTON, S.L. and SOUTHERN, L.L. (2000) The effect of varying mixes uniformity (stimulated) of phytase on growth performance, mineral retention, and bone mineralization in chicks. Poultry Science 79: 1485-1490.CrossRefGoogle Scholar
JONGBLOED, A.W and KEMME, P.A. (1990) Effect of pelleting mixed feeds on phytase activity and the apparent absorbability of phosphorus and calcium in pigs. Animal Feed Science and Technology 28: 233-242.CrossRefGoogle Scholar
JONDREVILLE, C., LESCOAT, P., MAGNIN, M., FEUERSTEIN, D., GRUENBERG, B. and NYS, Y. (2007) Sparing erect of microbial phytase on zinc supplementation in maize-soyabean meal diets for chickens. Animal 1(6): 804-811.CrossRefGoogle Scholar
KARIM, A. (2006) Responses of broiler chicks to non-phytate phosphorus levels and phytase supplementation. International Journal of Poultry Science 5 (3): 251-254.CrossRefGoogle Scholar
KIES, A.K., VAN HEMERT, K.H.F and SAUCER, W.C. (2001) Effect of phytase on protein and amino acid digestibility and energy retention. World's Poultry Science Journal 57: 109-126.CrossRefGoogle Scholar
KNUCKLES, B.E. and BETSCHART, A.A. (1987) Effect of phytate and other myo-inositol phosphate esters on alpha-amylase digestion of starch. Journal of Food Science 52: 719-721.CrossRefGoogle Scholar
KONDRA, P.A., SELL, J.L. and GUENTER, W. (1974) . Response of meat and egg type chickens to high fiber diet. Canadian Journal of Animal Science 54: 651-658.CrossRefGoogle Scholar
KORNEGAY, E.T. (1996a) Nutritional, environmental and economic considerations for using phytase in pig and poultry diets. In: KORNEGAY, E.T. (Ed).Nutrient management of food animals to enhance and protect the environment, pp. 277-302 (CRC Press, Boca Raton, FL).Google Scholar
KORNEGAY, E.T. (1996b) Effect of Natuphos phytase on protein and amino acid digestibility and nitrogen retention of poultry. In: COELHO, M.B. & KORNEGAY, E.T. (Eds) Phytase in Animal Nutrition and Waste Management, pp. 439-514 (BASF Corporation, Mount Olive, NJ).Google Scholar
KORNEGAY, E.T., RAVINDRAN, V. and DENBOW, D.M. (1996) Improving phytate phosphorus availability in corn and soyabean meal for broilers using microbial phytase and calculation of phosphorus equivalency values for phytase. Poultry Science 75: 240-249.Google Scholar
KORNEGAY, E.T., DENBOW, D.M. and ZHANG, Z. (1999) Influence of microbial phytase supplementation of a low protein/amino acid diet on performance, ileal digestibility of protein and amino acids, and carcass measurements of finishing broilers. In: COELHO, M.B. & KORNEGAY, E.T. (Eds) Phytase in Animal Nutrition and Waste Management, pp. 557-572 (BASF Corporation, Mount Olive, NJ).Google Scholar
KRATZER, F.H., ALFRED, J.B., DAVIS, P.N., MARSHALL, B.J. and VOHRA, V. (1959) The effect of autoclaving soyabean protein and the addition of ethylenediamine tetra-acetic acid on biological activity of dietary zinc for turkey poults. Journal of Nutrition 68: 313-23.CrossRefGoogle Scholar
KUNDU, B., BISWAS, P., RAJENDRAN, D. and DANDOPATH, S.K. (2000) Effect of supplementation of phytase enzyme and gradual replacement of dicalcium phosphate on the performance of commercial broker chicken. In: Proceedings of III Biennial conference of Animal Nutrition Association, Hisar, India. Abst. No. 128.Google Scholar
LEASE, J.G. (1966) The effect of autoclaving sesame meal on its phytic acid content and on the availability of its zinc to the chicks. Poultry Science 45:237-241.CrossRefGoogle Scholar
LEESON, S. (1993) Recent advances in fat utilization by poultry. In: FARRELL, D.J. (Ed) Recent Advance in Animal Nutrition in Australia, pp 170-181 (University of New England. Armidale, Australia).Google Scholar
LIENER, I.E. (1989) Anti nutritional factors in legume seeds: State of art. In: HUISMEN, J., VAN DER POEL, T.F.B. & LIENER, I.E. (Eds) Recent Advances of Research on Anti- nutritional Factors in Legume Seeds, pp. 6-13 (Pudoc, Wageningen, The Netherlands).Google Scholar
LIM, H.S., NAMKUNG, H., UM, J.S., KANG, K.R., KIM, B.S. and PAIK, I.K. (2000) The effect of phytase supplementation on the performance of broiler chickens fed diets with different levels of non-phytate phosphorus. Asian-Australasian Journal of Animal Sciences 14 (2): 250-257.CrossRefGoogle Scholar
LOTT, J.N.A. (1984) Accumulation of seed reserves of phosphorus and other minerals. In: MURRAY, D.R. (Ed) Seed Physiology, Vol.1, pp. 139-166 (Academic Press, London).Google Scholar
MA, X. and SHAN, A. (2002) Effect of germination and heating on phytase activity in cereal seeds. Asian Australasian Journal of Animal Sciences 15(7): 1036-1039.CrossRefGoogle Scholar
MADDAIAH, V.T., KUMICK, A.A., HULLET, B.J. and REID, B.L. (1964) Nature of intestinal phytase activity. Proceedings of the Society of Experimental Biology and Medicine 115:1054-1057.CrossRefGoogle ScholarPubMed
MAENZ, D.D., ENGELE-SCHAAN C.M., and CLASSEN, H.L. (1997) Endogenous phytase activity in the small intestinal brush border membrane of broiler chicks and laying hens. Poultry Science 76(suppl.): 71.Google Scholar
MAENZ, D.D. and CLASSEN, H.L. (1998) Phytase activity in the small intestinal brush border membrane of the chicken. Poultry Science 77: 557-563.CrossRefGoogle ScholarPubMed
MAGA, J.A. (1982) Phytate: its chemistry, occurrence, food interactions, nutritional significance and methods of analysis. Journal of Agricultural Food Chemistry 30: 1-9.CrossRefGoogle Scholar
MANANGI, M.K. and COON, C.K. (2006) .Evaluation of phytase enzyme with chicks fed basal diets containing different soyabean meal samples. Journal of Applied Poultry Research 15(2):292-306.CrossRefGoogle Scholar
McWARD, G.W. (1969) Effect of phytic acid and ethylenediamine tetra acetic acid (EDTA) on the chick requirement for magnesium. Poultry Science 48:791-794.CrossRefGoogle Scholar
McGRATH, J.M., SIMS, J.T., MAGURIE, R.O., SAYLOR, W.W., ANGEL, C.R. and TURNER, B.L. (2006) Broiler diet modification and litter storage: impact of phosphorus in litters, soils, and runoff. Journal of Environmental Quality 34(5): 1896-1909.Google Scholar
MILES, R.D. and NELSON, T.S. (1974) The effect of enzymatic hydrolysis of phytate on the available energy content of feed ingredients for chicken and rats . Poultry Science 53: 1714-1717.CrossRefGoogle Scholar
MILLER, G.A., YOUNGES, V.L. and OPLINGER, E.S. (1980) Effect of available soil phosphorus and environment on the phytic acid concentration in oats. Cereal Chemistry 57: 192.Google Scholar
MILLS, C.F. (1985) Dietary interactions involving the trace elements. Annual Review of Nutrition 5:173-175.CrossRefGoogle ScholarPubMed
MITCHELL, R.D. and EDWARDS, H.M. (1996) Effect of phytase and 1, 25-dihydroxycholecalciferol on phytate utilization and the quantitative requirement for calcium and phosphorus in young broiler chickens. Poultry Science 75: 95-110.CrossRefGoogle ScholarPubMed
MOHANNA, C. and NYS, N. (1999) Changes in zinc and manganese availability in broilers chicks induced by vegetal and microbial phytase. Animal Feed Science and Technology 77: 241-253.CrossRefGoogle Scholar
MOHAMMED, A., GIBNEY, M.J. and TAYLOR, T.G. (1991) The effect of dietary levels of inorganic phosphorus, calcium and cholecalciferol on the digestibility of phytate phosphorus by the chick. British Journal of Nutrition 66: 251-259.CrossRefGoogle ScholarPubMed
NAHM, K.H. (2003) Bioavailability of phosphorus in manure. Avian and Poultry Biology Reviews 14 (2): 53-62.CrossRefGoogle Scholar
NAMKUNG, H. and LEESON, S. (1999) Effect of phytase enzyme on dietary nitrogen-corrected apparent metabolizable energy and the ideal digestibility of nitrogen and amino acids. Poultry Science 78: 1317-1319.CrossRefGoogle Scholar
NAYANI, N.R. and MARKAKIS, P. (1986) Phytases. In: GRAF, E. (Ed.) Phytic acid: Chemistry and Applications, pp. 101-110 (Pitlatus Press, Minneapolis).Google Scholar
NELSON, T.S. (1967) The utilization of phytate phosphorus by poultry: a review. Poultry Science 46: 862-871.CrossRefGoogle ScholarPubMed
NELSON, T.S., SHIEH, T.R., WODZINSKI, R.J. and WARE, J.H. (1968) The availability of phytate phosphorus in soybean meal before and after treatment with a mould phytase. Poultry Science 47: 1842-1848.CrossRefGoogle ScholarPubMed
NELSON, T.S., SHIEH, T.R., WODZINSKI, R.J. and WARE, J.H. (1971) Effect of supplemental phytase on the utilization of phytate phosphorus by chicks. Journal of Nutrition 101: 1289-1294.CrossRefGoogle ScholarPubMed
NELSON, T.S. (1976) The hydrolysis of phytate phosphorus by chicks and laying hens. Poultry Science 55: 2262.CrossRefGoogle ScholarPubMed
NELSON, T.S. and KIRBY, L.K. (1987) The calcium binding properties of natural phytate in chick diets. Nutrition Report International 35: 949-956.Google Scholar
NELSON, T.S. and WALKER, A.C. (1964) The biological evaluation of phosphorus compounds: A summary. Poultry Science 43: 94-98.CrossRefGoogle Scholar
NEWKIRK, R.W. and CLASEN, H.L. (1995) Nutritional impact of canola meal phytate in broiler chicks. Poultry Science 74(Suppl.1): 14.Google Scholar
NOSWORTHY, N. and CALDWELL, R.A. (1988) The interaction of zinc (II) and phytic acid with soya bean glycinin. Journal of the Science of Food and Agriculture 44: 143-150.Google Scholar
NWOKOLO, E.N. and BRAGG, D.B. (1977) Influence of phytic acid and crude fiber on the availability of minerals from four protein supplements in growing chicks. Canadian Journal of Animal Science 57: 475-477.CrossRefGoogle Scholar
NRC, (1984) Nutrient Requirement of Poultry. Nutrients Requirements of Domestic Animals. 9th Edn. National Academy of Sciences, Washington, DC.Google Scholar
OBERLEAS, D. (1973) Phytate: In: Toxicants Occurring Naturally in Foods. National Academy of Sciences. Washington, DC, pp. 363-371.Google Scholar
OBERLEAS, D. and HARLAND, B.F. (1996) Impact of phytate on nutrient availability. In: COELHO, M..B. & KORNEGAY, E.T. (Eds) Phytase in Animal Nutrition and waste Management. BASF Corporation, Mount Olive, NJ.Google Scholar
O'DELL, B.L. (1962) Mineral availability and metal binding constituents of the diet. Proceedings of the Cornell Nutrition Conference of Feed Manufacturers, Ithaca, New York, pp.77-82.Google Scholar
O'DELL, B.L., DE BOLAND, A.R and KOIRTYOHANN, S.R. (1972) Distribution of phytate and nutritionally important elements among the morphological components of cereal grains. Journal of Agricultural Food Chemistry 20: 718-721.CrossRefGoogle Scholar
O'DELL, B.L. and DE BOLAND, A.R. (1976) Complexation of phytate with protein and cations in corn germ and oil seed meals. Journal of Agricultural Food Chemistry 24 (4): 804-808.CrossRefGoogle Scholar
OKUBO, K., MYERS, D.V. and IACOBUCCI, G.A. (1976) Binding of phytic to glycinin. Cereal Chemistry 53: 513-524.Google Scholar
OMOSAIYE, O. and CHERYAN, M. (1979) Low-phytate, full fat soy protein product by ultrafilteration of aqueous extracts of whole soyabean. Cereal Chemistry 56: 58-62.Google Scholar
PAIK, I. (2003) Application of phytase, Microbial or plant origin to reduce phosphorus excretion in poultry production. Asian-Australasian Journal of Animal Science 16(1): 124-135.CrossRefGoogle Scholar
PANDA, A.K., RAO, S.V.R., RAJU, M.V.L.N., GAUJA, S.S and BHANJA, S.K. (2007) Performance of broiler chickens fed low non phytate phosphorus diets supplemented with microbial phytase. Journal of Poultry Science 44(3): 258-264.CrossRefGoogle Scholar
PERNEY, K.M., CANTOR, A.H., STRAW, M.L. and HERKELMAN, K.L. (1993) The effect of dietary phytase on growth performance and phosphorus utilization of broiler chicks. Poultry Science 72: 2106-2114.CrossRefGoogle ScholarPubMed
PILLAI, P.B., O`CONNER, D.T., OWENS, C.M. and EMMERT, J.L. (2006) Efficacy of an Escherichia coli phytase in broilers fed adequate or reduced phosphorus diets and its effect on carcass characteristics. Poultry Science 85(10): 1737-1745.CrossRefGoogle Scholar
POINTILLART, A. (1988) Phytate phosphorus utilization in growing pigs. In: BURACZEWSKA, L., BURACZEWSKA, C. & ZEBROWSKA, T. (Eds) Digestive physiology in pigs , Proceeding of the 4th International Seminar, pp.192-196 (Polish Academy of Science, Jablona, Poland).Google Scholar
PENG, Y.L., GUO, Y. M. and YUAN, J.M. (2003) Effects of microbial phytase replacing partial inorganic phosphorus supplementation and xylanase on the growth performance and nutrient digestibility on broilers fed wheat based diets. Asian Australasian Journal of Animal Sciences 16(2): 239-247.CrossRefGoogle Scholar
PRATTLEY, C.A., STANLEY, D.W. and VANDER VOORT, F.R. (1982) Protein-phytate interactions in soya beans. II. Mechanism of protein-phytate bindings affected by calcium. Journal of Food Chemistry 6: 255-271.Google Scholar
POURREZA, J. and EBADI, M.R. (2006) Effect of supplemental phytase on metabolisable energy and nutrients digestibility of sorghum, corn and wheat. Journal of Science and Technology of Agriculture and Natural Resource 9(4): 191-200.Google Scholar
PUNNA, S. and ROLAND, S.R. (1999) Influence of supplemental phytase on first cycle laying hens fed phosphorus deficient diets from day one of age. Poultry Science 78: 1407-1411.CrossRefGoogle ScholarPubMed
QIAN, H., KORNEGAY, E.T. and DENBOW, D.W. (1995) Utilization of phytate phosphorus and calcium as influenced by microbial phytase, vitamin D3 and the calcium: total phosphorus ratios in broiler diets. Poultry Science 74(Suppl.1): 126.Google Scholar
QIAN, H., KORNEGAY, E.T. and DENBOW, D.W. (1996) Phosphorus equivalence of microbial phytase in turkeys diets as influenced by calcium to phosphorus ratios and phosphorus levels. Poultry Science 75: 69-81.CrossRefGoogle ScholarPubMed
RAMA RAO, S.V., REDDY, V.R. and REDDY, R.S. (1999) Enhancement of phytate phosphorus availability in the diets of commercial broilers and layers. Animal Feed Science and Technology 79: 211-222.CrossRefGoogle Scholar
RAVINDRAN, V., RAVINDRAN, G. and SIVALOGAN, S. (1994) Total and phytate phosphorus contents of various foods and feedstuffs of plant origin. Food Chemistry 50: 133-136.CrossRefGoogle Scholar
RAVIDRAN, V., BRYDEN, W.L. and KORNEGAY, E.T. (1995) Phytates: Occurrence, bioavailability and implications in poultry nutrition. Poultry and Avian Biology Review 6 (2): 125-143.Google Scholar
RAVINDRAN, V., CARBAHUG, S., RAVINDRAN, G. and BRYDEN, W.L. (1999a) Influence of microbial phytase on apparent ileal amino acid digestibility in feedstuffs for broilers. Poultry Science 78: 699-706.CrossRefGoogle ScholarPubMed
RAVINDRAN, V., HEW, LI., RAVINDRAN, G. and BRYDEN, W.L. (1999b) A comparison of ileal digesta and excreta analysis for the determination of amino acid digestibility in food ingredients for poultry. British Poultry Science 40: 266-274.CrossRefGoogle ScholarPubMed
RAVINDRAN, V., CARBAHUG, S., RAVINDRAN, G., SELLE, P.H. and BRYDEN, W.L. (2000) Response of broiler chickens to microbial phytase supplementation as influenced by dietary phytic acid and non-phytate phosphorous levels. II. Effects on apparent metabolisable energy, nutrient digestibility and nutrient retention. British Poultry Science 41: 193-200.CrossRefGoogle ScholarPubMed
RAVINDRAN, V., SELLE, P.H., RAVINDRAN, G., MOREL, P.C.H., KIES, A.K. and BRYDEN, W.L. (2001) Influence of supplemental microbial phytase on the performance, apparent metabolizable energy, and ileal amino acid digestibility of broilers fed a lysine-deficient diet. Poultry Science 80: 338-344.CrossRefGoogle Scholar
REDDY N.R., SATHE S.K. and SALUNKHE D.K., (1982) Phytates in legumes and cereals. Advances in Food Research 28: 1-9.CrossRefGoogle ScholarPubMed
REID, R.L. and FRANKLIN, M.C. (1947) The utilization phytate-phosphorus by sheep. Australian Veterinary Journal 23:136-140.CrossRefGoogle Scholar
ROBERSON, K.D. and EDWARDS, H.M. (1994) Effects of 1, 25-dihydroxycholecalciferol and phytase on zinc utilization in broiler chicks. Poultry Science 73:1312-1326.CrossRefGoogle ScholarPubMed
RUTHERFORD, S.M., EDWARDS, E.C.A. and SELLE, P.H. (1997) Effect of phytase on lycine-rich polard complexes. In: CRANWELL, P.D. (Ed) Manipulating Pig Production, Vol. 6 (Australasian Pig Science Association, Werribee, Victoria).Google Scholar
SAITOH, M. (2001) The trend of studies on reducing nutrient excretion in poultry and pigs by nutritional approaches. Animal Science Journal 72 (8): 177-199.Google Scholar
SCHEIRDELERM, S.E. and SELL, J.L. (1987) Utilization of phytate phosphorus in laying hens as influenced by dietary phosphorus and calcium. Nutritional Report International 35: 1073.Google Scholar
SCHEURMANN, S.E. VON, LANTZSCH, H.L. and MENKE, K.H. (1988) In vivo experiments on the hydrolysis of phytate. 2. Activity of plant phytase. Journal of Animal Physiology and Animal Nutrition 60: 64.Google Scholar
SCHINDLER, D.N. (1977) The evaluation of phosphorus limitation in lakes. Science 195: 260-263.CrossRefGoogle Scholar
SCHONER, F.J., HOPPE, P.P., SCHWARZ, G. and WIESCHE, H. (1993) Effect of microbial phytase and inorganic phosphate in broiler chickens: performance and mineral retention at various calcium levels. Journal of Animal Physiology and Animal Nutrition 69: 235-244.Google Scholar
SEBASTIAN, S., TOUCHBURN, S.P. and CHAVEZ, E.R. (1994) Enhancement of mineral utilization and growth performance of broilers chickens by microbial phytase supplementation of a corn-soyabean meal diet. Proceedings of XX world's poultry congress, World's Poultry Science Journal Association, New Delhi, India.Google Scholar
SEBASTIAN, S., TOUCHBURN, S.P., CHAVEZ, E.R. and LAGUE, P.C. (1996a) The effects of supplemental microbial phytase on the performance and utilization of dietary calcium, phosphorus, copper and zinc in broiler chickens fed corn-soyabean diets. Poultry Science 75: 729-736.CrossRefGoogle Scholar
SEBASTIAN, S., TOUCHBURN, S.P., CHAVEZ, E.R. and LAGUE, P.C. (1996b) Efficacy of supplemental microbial phytase at different dietary calcium levels on growth performance and mineral utilization of broiler chickens. Poultry Science 75: 1516-1523.CrossRefGoogle ScholarPubMed
SEBASTIAN, S., TOUCHBURN, S.P., CHAVEZ, E.R. and LAGUE, P.C. (1997) Apparent digestibility of protein and amino acids in broiler chickens fed a corn-soybean diet supplemented with microbial phytase. Poultry Science 76: 1760-1769.CrossRefGoogle ScholarPubMed
SEBASTIAN, S., TOUCH BURN, S.P. and CHAVEZ, E.R. (1998) Implications of Phytic acid and supplemented microbial phytase in poultry nutrition: a review. World's Poultry Science Journal 54: 27-47.CrossRefGoogle Scholar
SELLE, P.H., RAVINDRAN, V., CALDWELL, R.A. and BRYDEN, W.L. (2000) Phytate and phytase: consequences for protein utilization. Nutrition Research and Review 13: 255-278.CrossRefGoogle Scholar
SELLE, P.H., CRESWELL, D.C., CADAGON, D.J., PARTRIDGE, G.G. and SCOTT, T.T. (2006) Phytase supplementation of wheat based broiler diets reduces dependence on meat and bone meal. Journal of Poultry Science 43(4): 330.338.CrossRefGoogle Scholar
SELLE, P.H., RAVINDRAN, V., RAVINDRAN, G. and BRYDEN, W.L. (2007) Effect of dietary lysine and microbial phytase on growth performance and nutrient utilization of broiler chickens. Asian-Australasian Journal of Animal Sciences 20 (7): 1100-1107.CrossRefGoogle Scholar
SHAFEY, T.M., Mc DOANALD, M.W. and DINGLE, J.G. (1991) Effect of dietary calcium and available phosphorus concentration on intestinal pH and on the availability of calcium, iron, magnesium and zinc from the intestinal contents of meat chickens. British Poultry Science 32: 185-194.CrossRefGoogle ScholarPubMed
SIMONS, P.C.M., VERSTEEGH, H.A.J., JONGBLOED, A. W., KEMME, P.A., SLUMP, P., BOS, K.D., WOLTERS, M.G.E., BEUDEKER, R.F. and VERSCHOOOR, G.J. (1990) Improvement of phosphorus availability by microbial phytase in broilers and pigs. British Journal of Nutrition 64: 525-540.CrossRefGoogle ScholarPubMed
SINGH, M. and KRIKORIAN, A.D. (1982) Inhibition of trypsin activity in vitro by phytate. Journal of Agriculture and Food Chemistry 30: 799-800.CrossRefGoogle Scholar
SINGH, J. and SIKKA, S.S. (2006) Effect of phytase supplementation at different Ca:P ratios of the growth performance of broiler chicks. Indian Journal of Poultry Science 41 (2): 159-164.Google Scholar
SINGH, P.K. (2002) Utilisation of phytic acid in poultry diets. Poultry Planner. 3 (11): 17-19.Google Scholar
SINGH, P.K. and KHATTA, V.K. (2002) Phytase supplementation for economic and eco-friendly broiler production. Journal of Eco- Physiology 5 (3-4): 117-121.Google Scholar
SINGH, P.K. and KHATTA, V.K. (2003a) Effect of phytase supplementation on the performance of broiler chickens fed wheat based diets. Indian Journal of Animal Nutrition 20 (1): 57-62.Google Scholar
SINGH, P.K. and KHATTA, V.K. (2003b) Effect of phytase supplementation on the broiler production. Poultry Planner 4 (10): 13-14.Google Scholar
SINGH, P.K., KHATTA, V.K. and THAKUR, R.S. (2003a) Effect of phytase supplementation in maize based diet on growth performance and nutrients utilization of broiler chickens. Indian Journal of Animal Sciences 73 (4): 455-458.Google Scholar
SINGH, P.K., KHATTA, V.K., THAKUR, R.S., DEY, S. and SANGWAN, M.L. (2003b) Effects of phytase supplementation on the performance of broiler chickens fed maize and wheat based diets with different levels of non-phytate phosphorus. Asian-Australasian Journal of Animal Sciences 16 (11): 1642-1649.CrossRefGoogle Scholar
SINGH, P.K. and KHATTA, V.K. (2004) Economics of broilers raised on phytase-supplemented diets. Indian Journal of Animal Research 10 (2): 121-124.Google Scholar
SINGH, P.K. (2004) Wheat: An alternative of maize in poultry rations? Poultry Line 4 (10): 23-26.Google Scholar
SOHAIL, S.S. and ROLAND, S.R. (2000) Influence of phytase on calcium utilization in commercial layers. Journal of Applied Poultry Research 9: 81-87.CrossRefGoogle Scholar
SUKUMAR, D. and JALAUDEEN, A. (2003) Effect of supplemental phytase in diets on certain economic traits in layer chickens. Indian Journal of Animal Sciences 73 (12): 1357-1359.Google Scholar
TAYLOR, T.G. (1965) The availability of the calcium and phosphorus of plant materials for animals. Proceedings of the Nutrition Society 24:633-637.CrossRefGoogle ScholarPubMed
TEMPERTON, H., DUDLEY, J. and PICKERING, G.L. (1965a) Phosphorus requirement of poultry. IV. The effects on growing pullets on feeding diets containing no animal protein or supplementary phosphorus. British Poultry Science 6:125-133.CrossRefGoogle ScholarPubMed
TEMPERTON, H., DUDLEY, J. and PICKERING, G.L. (1965b) Phosphorus requirement of poultry. V. The effects during the subsequent laying year of feeding growing diets containing no animal protein or supplementary phosphorus. British Poultry Science 6: 135-141.CrossRefGoogle ScholarPubMed
THOMPSON, L.U. and YOON, J.H. (1984) Starch digestibility as affected by poly phenols and phytic acid. Journal of Food Science 49: 1228-1229.CrossRefGoogle Scholar
TYAGI, P.K., TYAGI, P.K. and VERMA S.V.S., (1998) Phytate phosphorus content of some common poultry feed stuffs. Indian Journal of Poultry Science 33 (1): 86-88.Google Scholar
TURK, M., SANDBERG, A.S., CARLSSON, N.G. and ANDID, T. (2000) Inositol hexaphosphate hydrolysis by baker`s yeast, capacity, kinetics and degradation products. Journal of Agricultural and Food Chemistry 48: 100-104.CrossRefGoogle ScholarPubMed
VANDEPEPOPULIERE, J.M., AMMERMAN, C.B. and HARMS, R.M. (1961) The relationship of calcium: phosphorus ratios to the utilization of plant and inorganic phosphorus by the chick. Poultry Science 40: 951-958.CrossRefGoogle Scholar
VAN DER KLIS, J.D., VERSTEEGH, H.A.J., SIMONS, P.C.M and KIES, A.K. (1997) The efficacy of phytase in corn-soyabean meal based diets for laying hens. Poultry Science 76: 1535-1542.CrossRefGoogle Scholar
VINIL, S.P., KADIRVELAN, C., THIRUMALAI, S., VALLI, S. and CHANDRABOSE, B. (2000) The role of phytase and other enzymes in augmenting the bioavailability of nutrients in broilers. Proceedings of XX Annual conference of Indian Poultry Science Association, Chennai, India. Abst. No. PPN. 97.Google Scholar
VOHRA, P., GRAY, G.A. and KRATZER, F.H. (1965) Phytic acid-metal complexes. Proceedings of the Society of Experimental Biology and Medicine 120: 447.CrossRefGoogle ScholarPubMed
WALDROUP, P.W., AMMERMAN, C.B and HARMS, P. (1964) The availability of phytic acid phosphorus for chicks. 3. Effect of calcium and D3 levels on the utilization of calcium phytate. Poultry Science 43: 926-931.CrossRefGoogle Scholar
WALDROUP, P.W., KERSEY, J.H., SALEH, E.A., FRITIS, C.A., YAN, F., STILORN, H.L., CRUM, R.C. Jr. and RABOY, V. (2000) Non-phytate phosphorus requirement and phosphorus requirement and phosphorus excretion of broiler chicks fed diets composed of normal or high available phosphate corn with or without microbial phytase. Poultry Science 79: 1451-1459.CrossRefGoogle ScholarPubMed
WASSERMAN, R.H. and TAYLOR, A.N. (1973) Intestinal absorption of phosphorus in the chicks. Effect of vitamin D and other parameters. Journal of Nutrition 103: 586-599.CrossRefGoogle ScholarPubMed
WICKER, D.L. (1999) Phosphorus reduction techniques examined. Feedstuffs 71 (24): 12-14.Google Scholar
WISE, A. (1983) Dietary factors determining the biological activity of phytase. Nutrition Abstract and Reviews 53: 791-806.Google Scholar
WODZINSKI, R.J. and ULLAH, A.H.J. (1996) Phytase. Advances in Applied Microbiology 42: 263-303.CrossRefGoogle ScholarPubMed
YAN, F. and WALDROUP, R.W. (2006) Non-phytate phosphorus requirement and phosphorus excretion of broiler chicks fed diets composed of normal or high available phosphate corn as influenced by phytase supplementation and vitamin D source. International Journal of Poultry Science. 5(3): 219-228.Google Scholar
YI, Z., KORNEGAY, E.T. and MEGUIRK, A. (1994) Replacement value of inorganic phosphorus by microbial phytase for pigs and poultry. Journal of Animal Science 72(Suppl.1): 330.Google Scholar
YI, Z., KORNEGAY, E.T. and DENBOW, D.M. (1996a) Supplemental microbial phytase improves the zinc utilization in broilers. Poultry Science 75: 540-546.CrossRefGoogle ScholarPubMed
YI, Z., KORNEGAY, E.T. and DENBOW, D.M. (1996b) Effect of microbial phytase on nitrogen and amino acid digestibility and nitrogen retention of turkey poults fed corn-soyabean meal diets. Poultry Science 75: 979-990.CrossRefGoogle Scholar
ZANINI, S.F. and SAZZAD, M.H. (1999) Effect of microbial phytase on growth and mineral utilization in broiler fed on maize soyabean based diets. British Poultry Science 40: 348-352.CrossRefGoogle ScholarPubMed
ZHANG, X., KORNEGAY, , ROLAND, D.A., MCDANIEL, G.R. and RAO, S.K. (1999) . Effect of Natuphos® phytase supplementation to feed on performance and ileal digestibility of protein and amino acids in broilers. Poultry Science 78: 1567-1572.CrossRefGoogle Scholar