Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-22T18:38:23.007Z Has data issue: false hasContentIssue false
  • English
  • Français

Nutritional and immunological effects of nano-particles in commercial poultry birds

Published online by Cambridge University Press:  23 April 2019

M.I. ANWAR ,
M.M. AWAIS ,
M. AKHTAR ,
M.T. NAVID  and
F. MUHAMMAD
M.I. ANWAR*
Affiliation:
Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, Pakistan
M.M. AWAIS
Affiliation:
Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, Pakistan
M. AKHTAR
Affiliation:
Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, Pakistan
M.T. NAVID
Affiliation:
Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan
F. MUHAMMAD
Affiliation:
Institute of Pharmacy, Physiology and Pharmacology, Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan
*
Corresponding author: [email protected]
Get access

Abstract

The poultry industry is mainly scared by affected by infections due to microorganisms which reduce the growth rate and cause economic losses. Currently, vaccines and antibiotics are utilised to combat these infectious microorganisms, but irresponsible use of antibiotics may pose health risks to consumers, and there is a need for drug-free alternatives. Nanotechnology could reduce such risks and can improve the wholesomeness of poultry meat. This review discusses the current status of nanotechnology as it relates to improving poultry health by using various nano-particles (NPs). Silver-NPs at a dose rate of 900 ppm have been used in poultry to improve their growth performance in terms of body weight, feed intake and feed conversion ratio. NPs are thought to boost immunity in birds against numerous diseases. Gold-NPs improved the growth performance of poultry birds as well as detecting avian influenza virus with a detection limit of 2.2 pg/ml. Similarly, Copper-loaded chitosan-NPs supplementation at dose rate of 100 mg/kg feed improved growth performance, immunity, protein synthesis and caecal microbiota in broilers. Zinc oxide-NPs improved growth performance and showed anti-oxidative properties in broilers at the dose rate of 20 mg/kg. While, montmorillonite nano-composites at a level of 3 g/kg feed decreased the toxicity of aflatoxins in poultry birds. In conclusion, nanotechnology has the potential to reduce microbial load without resulting drug residues in poultry products, thus improving performance and immune status of poultry birds.

Keywords

nano-particlespoultryproductivitygrowth performancedisease control
Type
Review
Information
World's Poultry Science Journal , Volume 75 , Issue 2 , June 2019 , pp. 261 - 272
Copyright
Copyright © World's Poultry Science Association 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ADAIR, B.M. (2009) Nanoparticle vaccines against respiratory viruses. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 1: 405-414.Google Scholar
AHMADI, F. and KURDESTANY, A.H. (2010) The impact of silver nano particles on growth performance, lymphoidorgans and oxidative stress indicators in broiler chicks. Global Veterinaria 5: 366-370.Google Scholar
AHMADI, J. (2009) Application of Different Levels of Silver Nanoparticles in Food on the Performance and Some Blood Parameters of Broiler Chickens. World Applied Sciences Journal 7 (1): 24-27.Google Scholar
ALISHAHI, A. (2014) Antibacterial effect of chitosan nanoparticle loaded with nisin for the prolonged effect. Journal of Food Safety 32 (2): 111-118.Google Scholar
BAKOWICZ, K. and MITURA, S. (2002) Biocompatibility of NCD. Journal of Wide Band gap Materials 9: 261-272.Google Scholar
BENTOLILA, L.A., EBENSTEIN, Y. and WEISS, S. (2009) Quantum dots for in vivo small-animal imaging. Journal of Nuclear Medicine 50: 493-496.Google Scholar
BHANJA, S.K., ANNA, H., MANISH, M., EWA, S., LANE, P., KRISHNA, P.V., NATALIA, K. and ANDRÉ, C. (2015) In Ovo administration of silver nanoparticles and/or amino acids influence metabolism and immune gene expression in chicken embryos. International Journal of Molecular Sciences 16: 9484-9503.Google Scholar
BRATZ, K., GOLZ, G., RIEDEL, C., JANCZYK, P., NOCKLER, K. and ALTER, T. (2013) Inhibitory effect of high-dosage zinc oxide dietary supplementation on Campylobacter coli excretion in weaned piglets. Journal of Applied Microbiology 115 (5): 1194-1202.Google Scholar
BROOM, L.J., MILLER, H.M., KERR, K.G. and TOPLIS, P. (2003) Removal of both zinc oxide and avilamycin from the post-weaning piglet diet: consequences for performance through to slaughter. Animal Science Journal 77: 79-84.Google Scholar
CAI, C., QU, X.Y., WEI, Y.H. and YANG, A.Q. (2013) Nano-selenium: nutritional characteristics and application in chickens. Chinese Journal of Animal Nutrition 12: 2818-2823.Google Scholar
CAI, S. (2012) The biology characteristics of nano-selenium and its application in livestock and poultry. China Feed Additives 10: 10-12.Google Scholar
CARMEN, I.M., CHITHRA, P.P., QINGRONG, H., PAUL, T., SEAN, L. and KOKINI, J.L. (2003) Nanotechnology: A New Frontier in Food Science. Food Technology 57: 24-29.Google Scholar
CASE, C.L. and CARLSON, M.S. (2002) Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs. Journal of Animal Science 80 (7): 1917-1924.Google Scholar
CHEN, X. and MORAN, E.T. (1995) The withdrawal feed of broilers: Carcass responses to dietary phosphorus. The Journal of Applied Poultry Research 4: 69-82.Google Scholar
CHO, K.H., PARK, J.E., OSAKA, T. and PARK, S.G. (2005) The study of antimicrobial activity and preservative effects of nanosilver ingredient. Electrochimica Acta 15: 956-960.Google Scholar
DAI, C., HONG, K., WANQIU, Y., JINYAN, S., CHUNLONG, L., GUOGANG, C., GUANGYU, R., XIAOHUA, W., XIN, W., ZHENG, J. and KAI, Z. (2015) O-2’-Hydroxypropyltrimethyl ammonium chloride chitosannanoparticles for the delivery of live Newcastle disease vaccine. Carbohydrate Polymers 130: 280-289.Google Scholar
DE JONG, W.H. and BORM, P.J. (2008) Drug delivery and nanoparticles: applications and hazards. International Journal of Nanomedicine 3: 133-149.Google Scholar
DOBRZANSKI, Z., ZYGADILK, K., PATKOWSKA-SOKOLA, B., NOWA-KOWSKI, P., JANCZAK, M., SOBCZAK, A. and BODKOWSKI, R. (2010) The effectiveness of nanosilver and mineral sorbents in the reduction of ammonia emissions from livestock manure. Przemysl Chemiczny 4: 348-351 (in Polish).Google Scholar
DOYLE, M.P., BUSTA, F., CORDS, B.R., DAVIDSON, P.M., HAWKE, J., HURD, H.S., ISAACSON, R.E., MATTHEWS, K., MAURER, J. and MENG, J. (2006) Antimicrobial resistance: implications for the food system: an expert report, funded by the IFT foundation. Comprehensive Reviews in Food Science and Food Safety 5: 71-137.Google Scholar
DUFFY, L.L., OSMOND-MCLEOD, M.J., JUDY, J. and KING, T. (2018) Investigation into the antibacterial activity of silver, zinc oxide and copper oxide nanoparticles against poultry-relevant isolates of Salmonella and Campylobacter. Food Control 92: 293-300.Google Scholar
ELKLOUB, K.M., MOUSTAFA, E.L., GHAZALAH, A.A. and REHAN, A.A.A. (2015) Effect of dietary nanosilver on broiler performance. International Journal of Poultry Science 14 (3): 177-182.Google Scholar
EMAMI, T., MADANI, R., REZAYAT, S.M., GOLCHINFAR, F. and SARKAR, S. (2012) Applying of gold nanoparticle to avoid diffusion of the conserved peptide of avian influenza nonstructural protein from membrane in Western blot. The Journal of Applied Poultry Research 21: 563-566.Google Scholar
ESFAHANI, M., FARHAD, A. and MOHAMMAD, A.A. (2015) The effects of different levels of Curcuma longa and zinc oxide nanoparticles on the quality traits of thigh and breast meat in broiler chickens. International Journal of Biosciences 6 (3): 296-302.Google Scholar
FENG, J., MA, W.Q., NIU, H.H., WU, X.M., WANG, Y. and FENG, J. (2010) Effects of zinc glycine chelate on growth, hematological, and immunological characteristics in broilers. Biological Trace Element Research 133 (2): 203-211.Google Scholar
GRODZIK, M. and SAWOSZ, E. (2006) The influence of silver nano particles on chicken embryo development and bursa of fabricius morphology. Journal of Animal and Feed Sciences 15 (1): 111-114.Google Scholar
GRODZIK, M., SAWOSZ, F., SAWOSZ, E., HOTOWY, A., WIERZBICKI, M., KUTWIN, M., JAWORSKI, S. and CHWALIBOG, A. (2013) Nano-nutrition of chicken embryos. The effect of in ovo administration of diamond nanoparticles and L-glutamine on molecular responses in chicken embryo pectoral muscles. International Journal of Molecular Sciences 14 (11): 23033-23044.Google Scholar
HAMZA, Z., EL-HASHASH, M., ALY, S., HATHOUT, A., SOTO, E., SABRY, B., OSTROFF, G. (2019) Preparation and characterization of yeast cell wall beta-glucan encapsulated humic acid nanoparticles as an enhanced aflatoxin B1 binder. Carbohydrate polymers 203: 185-192.Google Scholar
ILLUM, L. (1998) Chitosan and its use as a pharmaceutical excipient. Pharmaceutical Research 15 (9): 1326-1331.Google Scholar
JAN, S.S., DENG-CHENG, L., XIAO-YING, D., YONG-MING, H. and JIN-DING, C. (2012) Effects of chitosan and its derivative added to water on immunological enhancement and disease control. Immunotherapy 4 (7): 697-701.Google Scholar
JAROCKA, U., RÓŻA, S., ANNA, G.S., AGNIESZKA, S., WŁODZIMIERZ, Z.O., JERZY, R. and HANNA, R. (2014) An immunosensor based on antibody binding fragments attached to gold nanoparticles for the detection of peptides derived from avian influenza hemagglutinin H5. Sensors 14: 15714-15728.Google Scholar
KARIMI, A., SADEGHI, G. and VAZIRI, A. (2011) The effect of copper in excess of the requirement during the starter period on subsequent performance of broiler chicks. The Journal of Applied Poultry Research 20: 203-209.Google Scholar
KHALILI, I., RAHIM, G., SAEED, S.E., MOHSEN, F.N., MOHAMMAD, M.E., NASER, G., YOUSEF, S.H. and MOHAMMAD, T.K. (2015) Evaluation of immune response against inactivated avian influenza (H9N2) vaccine, by using chitosan nanoparticles. Jundishapur Journal of Microbiology 8 (12): e27035.Google Scholar
KIETZMANN, M. and BRAUN, M. (2006) Effects of the zinc oxide and cod liver oil containing ointment zincojecol in an animal model of wound healing. Deutsche Tierärztliche Wochenschrift 113 (9): 331-334.Google Scholar
KIM, H.J., KIM, S.H., LEE, J.K., CHOI, C.U., LEE, H.S., KANG, H.G. and CHA, S.H. (2012) A novel mycotoxin purification system using magnetic nanoparticles for the recovery of aflatoxin B1 and zearalenone from feed. Journal of Veterinary Science 13 (4): 363-369.Google Scholar
LAURENT, S., FORGE, D., PORT, M., ROCH, A., ROBIC, C., VANDER ELST, L. and MULLER, R.N. (2008) Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chemical Reviews 108 (6): 2064-2110.Google Scholar
LEENAARS, P.P., HENDRIKSEN, C.F., KOEDAM, M.A., CLAASSEN, I. and CLAASSEN, E. (1995) Comparison of adjuvants for immune potentiating properties and side effects in mice. Veterinary Immunology and Immunopathology 48 (1-2): 123-138.Google Scholar
LEESON, S. (2009) Copper metabolism and dietary needs. World's Poultry Science Journal 65: 353-366.Google Scholar
LIU, Z.H., LU, L., LI, S.F., ZHANG, L.Y., XI, L., ZHANG, K.Y. and LUO, X.G. (2011) Effects of supplemental zinc source and level on growth performance, carcass traits, and meat quality of broilers. Poultry Science 90 (8): 1782-1790.Google Scholar
LUCAS, J.M. (2010) Microarrays: Molecular allergology and nanotechnology for personalised medicine (II). Allergologia Immunopathologia (Madr) 38 (4): 217-223.Google Scholar
MAHLER, G.J., MANDY, B.E., ELAD, T., TERESA, L.S., SHIVAUN, D.A., RAYMOND, P.G. and MICHAEL, L.S. (2012) Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology 7: 264-271.Google Scholar
MATSUMURA, Y., YOSHIKATA, K., KUNISAKI, S. and TSUCHIDO, T. (2003) Mode of bactericidal action of silver zeolite and its comparison with that of silver nitrate. Applied and Environmental Microbiology 69: 4278-4281.Google Scholar
MIROSHNIKOV, S.A., ELENA, V.Y., ELENA, A.S., ELENA, P.M. and VLADIMIR, I.L. (2015) Comparative assessment of effect of copper nano- and microparticles in chicken. Oriental Journal of Chemistry 31 (4): 2327-2336.Google Scholar
MOHAMMADI, F., AHMADI, F. and AMIRI, A.M. (2015) Effect of zinc oxide nanoparticles on carcass parameters, relative weight of digestive and lymphoid organs of broiler fed wet diet during the starter period. International Journal of Biosciences 6 (2): 389-394.Google Scholar
MROCZEK-SOSNOWSKA, N., ŁUKASIEWICZ, M., ADAMEK, D., KAMASZEWSKI, M., NIEMIEC, J., WNUK-GNICH, A., SCOTT, A., CHWALIBOG, A. and SAWOSZ, E. (2017) Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens. Archives of Animal Nutrition 71 (4): 327-332.Google Scholar
MROCZEK-SOSNOWSKA, N., ŁUKASIEWICZ, M., WNUK, A., SAWOSZ, E. and NIEMIEC, J. (2014) Effect of copper nanoparticles and copper sulfate administered in ovo on copper content in breast muscle, liver and spleen of broiler chickens. Annals of Warsaw University of Life Sciences - SGGW. Animal Science 53: 135-142.Google Scholar
MROCZEK‐SOSNOWSKA, N., ŁUKASIEWICZ, M., WNUK, A., SAWOSZ, E., NIEMIEC, J., SKOT, A., JAWORSKI, S. and CHWALIBOG, A. (2016) In ovo administration of copper nanoparticles and copper sulfate positively influences chicken performance. Journal of the Science of Food and Agriculture 96 (9): 3058-3062.Google Scholar
MROCZEK-SOSNOWSKA, N., SAWOSZ, E., VADALASETTY, K.P., ŁUKASIEWICZ, M., NIEMIEC, J., WIERZBICKI, M., KUTWIN, M., JAWORSKI, S. and CHWALIBOG, A. (2015) Nanoparticles of copper stimulate angiogenesis at systemic and molecular level. International Journal of Molecular Sciences 16 (3): 4838-4849.Google Scholar
NYGAARD, U.C., HANSEN, J.S., SAMUELSEN, M., ALBERG, T., MARIOARA, C.D. and LØVIK, M. (2009) Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice. Toxicological Sciences 109 (1): 113-123.Google Scholar
OHIMAIN, E.I. and OFONGO, R.T.S. (2012) The effect of probiotic and prebiotic feed supplementation on chicken health and gut microflora: A review. International Journal of Animal and Veterinary Advances 4: 135-143.Google Scholar
PANGESTIKA, R. and ERNAWATI, R. (2017) Antiviral Activity Effect of Silver Nanoparticles (Agnps) Solution Against the Growth of Infectious Bursal Disease Virus on Embryonated Chicken Eggs with Elisa Test. KnE Life Sciences 3 (6): 536-548.Google Scholar
PARK, E.J., YI, J., KIM, Y., CHOI, K. and PARK, K. (2010) Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicology in Vitro 24 (3): 872-878.Google Scholar
PERCIVAL, S.L., BOWLER, P.G. and DOLMAN, J. (2007) Antimicrobial activity of silver-containing dressings on wound microorganisms using an in vitro biofilm model. International Wound Journal 4: 186-191.Google Scholar
PINEDA, L., CHWALIBOG, A., SAWOSZ, E., LAURIDSEN, C., ENGBERG, R., ELNIF, J., HOTOWY, A., SAWOSZ, F., GAO, Y., ALI, A. and MOGHADDAM, H.S. (2012) Effect of silver nanoparticles on growth performance, metabolism and microbial profile of broiler chickens. Archives of Animal Nutrition 66 (5): 416-429.Google Scholar
PINEDA, L., SAWOSZ, E., VADALASETTY, K.P. and CHWALIBOG, A. (2013) Effect of copper nanoparticles on metabolic rate and development of chicken embryos. Animal Feed Science and Technology 186: 125-129.Google Scholar
POULSEN, H.D. (1995) Zinc oxide for weanling piglets. Acta Agriculturae Scandinavica, Section A - Animal Science 45 (3): 159-167.Google Scholar
SAKI, A.A. and SALARY, J. (2015) The impact of in ovo injection of silver nanoparticles, thyme and savory extracts in broiler breeder eggs on growth performance, lymphoid-organ weights, and blood and immune parameters of broiler chicks. Poultry Science Journal 3 (2): 165-172.Google Scholar
SAWOSZ, E., GRODZIK, M., ZIELIŃSKA, M., NIEMIEC, T., OLSZAŃSKA, B. and CHWALIBOG, A. (2009) Nanoparticles of silver do not affect growth, development and DNA oxidative damage in chicken embryos. Archiv für Geflügelkunde 73 (3): 208-213.Google Scholar
SAWOSZ, E., ŁUKASIEWICZ, M., ŁOZICKI, A., SOSNOWSKA, M., JAWORSKI, S., NIEMIEC, J., SCOTT, A., JANKOWSKI, J., JÓZEFIAK, D. and CHWALIBOG, A. (2018) Effect of copper nanoparticles on the mineral content of tissues and droppings, and growth of chickens. Archives of Animal Nutrition 72 (5): 396-406.Google Scholar
SCHEERLINCK, J.P., GLOSTER, S., GAMVRELLIS, A., MOTTRAM, P.L. and PLEBANSKI, M. (2006) Systemic immune responses in sheep, induced by a novel nano-bead adjuvant. Vaccine 24 (8): 1124-1131.Google Scholar
SCHRAND, A.M., HUANGM, H., CARLSON, C., SCHLAGER, J.J., OMACR, S.E., HUSSAIN, S.M. and DAI, L. (2007) Are diamond nanoparticles cytotoxic? Journal of Physical Chemistry 111: 2-7.Google Scholar
SCOTT, N.R. (2005) Nanotechnology and animal health. Revue Scientifique et Technique 24 (1): 425-432.Google Scholar
SELIM, N.A., REFAIE, A.M., ABEER, R.K. and ABD EL-HAKIM, A.S. (2014) Effect of sources and inclusion levels of zinc in broiler diets containing different vegetable oils during summer season conditions on meat quality. International Journal of Poultry Science 13 (11): 619-626.Google Scholar
SENTHIL, K.C.K., SUGAPRIYA, S., MANIVANNAN, N. and CHANDAR, S.B. (2015) Effect on the growth performance of broiler chickens by selenium nanoparticles supplementation. Nano Vision 5 (4-6): 161-168.Google Scholar
SHI, Y.H., XU, Z.R., FENG, J.L. and WANG, C.Z. (2006) Efficacy of modified montmorillonite nanocomposite to reduce the toxicity of aflatoxin in broiler chicks. Animal Feed Science and Technology 129: 138-148.Google Scholar
SINHA, R., KIM, G.J., NIE, S. and SHIN, D.M. (2006) Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Molecular Cancer Therapeutics 5 (8): 1909-1917.Google Scholar
SUNDARESAN, N.R., ANISH, D., SASTRY, K.V.H., SAXENA, V.K., NAGARAJAN, K., SUBRAMANI, J., LEO, M.D.M., SHIT, N., MOHAN, J., SAXENA, M. and AHMED, K.A. (2008) High doses of dietary zinc induce cytokines, chemokines, and apoptosis in reproductive tissues during regression. Cell and Tissue Research 332 (3): 543-554.Google Scholar
TAN, M.J., ZHONG, S., LI, J., CHEN, Z. and CHEN, W. (2013) Air-stable efficient inverted polymer solar cells using solution-processed nanocrystalline ZnO interfacial layer. ACS Applied Materials & Interfaces 5 (11): 4696-4701.Google Scholar
TSUZUKI, T., HE, R., WANG, J., SUN, L. and WANG, X. (2012) Reduction of the photocatalytic activity of ZnO nanoparticles for UV protection applications. International Journal of Nanotechnology 9 (10-12SI): 1017-1029.Google Scholar
VIJAYAKUMAR, M.P. and BALAKRISHNAN, V. (2014) Effect of Calcium Phosphate Nanoparticles Supplementation on Growth Performance of Broiler Chicken. Indian Journal of Science and Technology 7 (8): 1149-1154.Google Scholar
WANG, C., WANG, M.Q., YE, S.S., TAO, W.J. and DU, Y.J. (2011) Effects of copper-loaded chitosan nanoparticles on growth and immunity in broilers. Poultry Science 90: 2223-2228.Google Scholar
WRIGHT, J.B., LAM, K., BURET, A.G., OLSON, M.E. and BURRELL, R.E. (2002) Early healing events in a porcine model of contaminated wounds: effects of nanocristalline silver on matrix metalloproteinases, cell apoptosis and healing. Wound Repair Regeneration 10: 141.Google Scholar
XU, Y., TANG, H., LIU, J.H., WANG, H. and LIU, Y. (2013) Evaluation of the adjuvant effect of silver nanoparticles both in vitro and in vivo. Toxicology letters 219 (1): 42-48.Google Scholar
YANG, T., GAN, Y.N., SONG, Z.F., ZHAO, T.T. and GONG, Y.S. (2014) Effects of different sources and levels of Vitamin D3 on performance, eggshell quality and tibial quality of laying hens. Chinese Journal of Animal Nutrition 3: 659-666.Google Scholar
ZHANG, X.Y., YIN, J.L., KANG, C., LI, J., ZHU, Y., LI, W., HUANG, Q. and ZHU, Z. (2010) Biodistribution and toxicity of nanodiamonds in mice after intratracheal instillation. Toxicology Letters 198: 237-243.Google Scholar
ZHAO, C.Y., SHU-XIAN, T., XI-YU, X., XIAN-SHUAI, Q., JIA-QIANG, P. and ZHAO-XIN, T. (2014) Effects of dietary zinc oxide nanoparticles on growth performance and antioxidative status in broilers. Biological Trace Element Research 160: 361-367.Google Scholar
ZHU, Y., LI, J., LI, W., ZHANG, Y., YANG, X., CHEN, N., SUN, Y., ZHAO, Y., FAN, C. and HUANG, Q. (2012) The biocompatibility of nanodiamonds and their application in drug delivery systems. Theranostics 2: 302-312.Google Scholar
ZIELIŃSKA, M.K., SAWOSZ, E., CHWALIBOG, A., OSTASZEWSKA, T., KAMASZEWSKI, M., GRODZIK, M. and SKOMIA, J. (2010) Nano-nutrition of chicken embryos. Effect of gold and taurine nanoparticles on muscle development. Journal of Animal and Feed Sciences 19: 277-285.Google Scholar