Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-22T19:05:48.093Z Has data issue: false hasContentIssue false
  • English
  • Français

The benefits of supplementation with antibiotic alternatives on Newcastle disease virus titres in poultry

Published online by Cambridge University Press:  12 September 2018

A.O. EMECHETA ,
A.C. IKE ,
C.J. ONU ,
C.D. EZE  and
C.V. OLOVO
A.O. EMECHETA
Affiliation:
Department of Microbiology, University of Nigeria, Nsukka, Nigeria
A.C. IKE*
Affiliation:
Department of Microbiology, University of Nigeria, Nsukka, Nigeria
C.J. ONU
Affiliation:
Department of Microbiology, University of Nigeria, Nsukka, Nigeria Department of Biotechnology, Osaka University, Japan
C.D. EZE
Affiliation:
Department of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka, Nigeria
C.V. OLOVO
Affiliation:
Department of Microbiology, University of Nigeria, Nsukka, Nigeria
*
Corresponding author: [email protected]
Get access

Abstract

Newcastle disease is one of the most important diseases of poultry with wide distribution and high fatalities. An infection with a virulent strain can cause up to 100% fatality in a susceptible flock, with devastating economic losses. In-feed antibiotics are not directly effective against Newcastle disease virus (NDV), but they may assist in prevent associated production problems. With in-feed antibiotics being controlled or banned, prebiotics, particularly those sourced from spices, and probiotics have been investigated as potential alternatives for maintaining seroconversion in poultry vaccinated against NDV. Certain prebiotics have a positive effect on anti-NDV antibodies but using spices as sources of prebiotics gave no clearly defined results. Garlic extract was reported to increase the mean haemagglutination inhibition (HI) titre of NDV by 0.6 after two weeks of supplementation, increasing titres by 4.0 in the vaccinated group compared to an increase of 3.4 in vaccinated unsupplemented group. However, onion-based compounds did not improve anti-NDV antibodies. The majority of studies have found that probiotics improved antibody levels and seroconversion to NDV vaccines in poultry. A commercial probiotic, containing a mixture of Bacillus species and Saccharomyces boulardii when used at a concentration of 100 g/ton was found to significantly increase the anti-NDV titre (log2) from 5.00 to 5.50. Another commercial probiotic, consisting of a combination of bacteria, reduced mortality by 6.6% at a concentration of 1 g/kg. Additional studies are needed to define the conditions and forms in which both the pre- and pro-biotics work best with respect to NDV control.

Keywords

Newcastle diseasevaccination titrespoultryprebioticprobioticyeastextracts
Type
Review
Information
World's Poultry Science Journal , Volume 74 , Issue 4 , December 2018 , pp. 665 - 674
Copyright
Copyright © World's Poultry Science Association 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ABOU-ELKHAIR, R., AHMED, H.A. and SELIM, S. (2014) Effects of black pepper (Piper nigrum), turmeric powder (Curcuma longa) and coriander seeds (Coriandrum sativum) and their combinations as feed additives on growth performance, carcass traits, some blood parameters and humoral immune response of broiler chickens. Asian-Australasian Journal of Animal Sciences 27 (6): 847-854.Google Scholar
ABUDABOS, A.M., ALYEMNI, A.H., DAFALLA, Y.M. and KHAN, R.U. (2017) Effect of organic acid blend and Bacillus subtilis alone or in combination on growth traits, blood biochemical and antioxidant status in broilers exposed to Salmonella typhimurium challenge during the starter phase. Journal of Applied Animal Research 45 (1): 538-542.Google Scholar
ADITYA, S., AHAMMED, M., JANG, H.S. and OHH, J.S. (2017) Effect of dietary onion (Allium cepa) extract supplementation on performance, apparent total tract retention of nutrients, blood profile and meat quality of broiler chicks. Asia-Australasian Journal of Animal Sciences 30 (2): 229-235.Google Scholar
AFONSO, C. and MILLER, P.J. (2013) Newcastle disease: progress and gaps in the development of vaccines and diagnostic tools. Developmental Biology (Basel) 135: 95-106.Google Scholar
AKTHAR, M.S., DEGAGA, B. and AZAM, T. (2014) Antimicrobial activity of essential oils extracted from medicinal plants against the pathogenic microorganisms: a review. Issues in Biological Sciences and Pharmaceutical Research 2 (1): 001-007.Google Scholar
ALEXANDER, D.J. (2011) Newcastle disease in the European Union 2000 to 2009. Avian Pathology 40: 547-558.Google Scholar
ALLOUI, N.M., AGABOU, A. and ALLOUI, N. (2014) Application of herbs and phytogenic feed additives in poultry production - a review. Global Journal of Animal Scientific Research 2 (3): 234-243.Google Scholar
AL-SULTAN, S.I., ABDEL-RAHEEM, S.M., EL-GHAREEB, W.R. and MOHAMED, M.H.A. (2016) Comparative effects of using prebiotic, probiotic, synbiotic and acidifier on growth performance, intestinal microbiology and histomorphology of broiler chicks. Japanese Journal of Veterinary Research 64 (2): S187-S195.Google Scholar
AMAGASE, H., PETESCH, L.B., MATSUURA, H., KASUGA, S. and ITAKURA, Y. (2001) Intake of garlic and its bioactive components. Journal of Nutrition 131: S955-S962.Google Scholar
ANKRI, S. and MIRELMAN, D. (1999) Antimicrobial properties of allicin from garlic. Microbes and Infection 2: 125-129.Google Scholar
ARNOLD, M., DURAIRAJ, V., MUNDT, E., SCHULZE, K., BREUNIG, K.D. and BEHRENS, S.E. (2012) Protective vaccination against infectious bursal disease virus with whole recombinant Kluyveromyces lactis yeast expressing the viral VP2 subunit. PLoS ONE 7(9): e42870.Google Scholar
BAYAN, L., KOULIVAND, P.H. and GORJI, A. (2014) Garlic: a review of potential therapeutic effects. Avicenna Journal of Phytomedicine 4 (1): 1-14.Google Scholar
BENKEBLIA, N. and SHIOMI, N. (2006) Fructooligosaccharides of edible Alliums: Occurrence, chemistry and health benefits. Current Nutrition and Food Science 2 (2): 181-191.Google Scholar
BLOCK, E. (1985) Chemistry of garlic and onions. Scientific American 252: 94-99.Google Scholar
BORLINGHAUS, J., ALBRECHT, F., GRUHLKE, C.H.M., NWACHUKWU, D.I. and SLUSARENKO, J.A. (2014) Allicin: chemistry and biological properties. Molecules 19: 12591-12618.Google Scholar
BOYLSTON, T.D., VINDEROLA, C.G., GHODDUSI, H.B. and REINHEIMER, J.A. (2004) Incorporation of Bifidobacteria into cheeses: Challenges and rewards. International Dairy Journal 14: 375-387.Google Scholar
CATTOLI, G., SUSTA, L., TERREGINO, C. and BROWN, C. (2011) Newcastle disease: a review of field recognition and current methods of laboratory detection. Journal of Veterinary Diagnostic Investigation 23 (4): 637-656.Google Scholar
CHEN, L., JIANG, T., LI, X., WANG, Q., WANG, Y. and LI, Y. (2016) Immunomodulatory activity of β- glucan and mannan-oligosaccharides from Saccharomyces cerevisiae on broiler chickens challenged with feed-borne Aspergillus fumigatus. Pakistan Veterinary Journal 36 (3): 297-301.Google Scholar
CHUGHTAI, S.A., KHAN, A.R., HUSSAIN, S. and IQBAL, S. (2015) Effect of multistrain probiotic on immune response and growth of broilers vaccinated against Newcastle disease. Pakistan Journal of Science 67 (3): 225-229.Google Scholar
CUMMINGS, J.H. and MACFARLANE, G.T. (2002) Gastrointestinal effects of prebiotics. British Journal of Nutrition 87 (2): 145-151.Google Scholar
DEMIR, E., ŞENAY, S., ÖZCAN, M.A. and SUIÇMEZ, M. (2005) The use of natural feed additives as alternative to an antibiotic growth promoter in broiler diets. Archiv für Geflügelkunde 69 (3): 110-116.Google Scholar
DIMITROV, K.M., RAMEY, A.M., QUI, X., BAHL, J. and AFONSO, C.L. (2016) Temporary, geographic, and host distribution of avian paramyxovirus 1 (Newcastle disease virus). Infection, Genetics and Evolution 39: 22-34.Google Scholar
DWIVEDI, S., SAHRAWAT, K., PUPPALA, N. and ORTIZ, R. (2014) Plant prebiotics and human health: biotechnology to breed prebiotic-rich nutritious food crops. Electronic Journal of Biotechnology 17 (5): 1-12.Google Scholar
EID, K.M. and IRAQI, M.M. (2014) Effect of garlic powder on growth performance and immune response for newcastle and avian influenza virus diseases in broiler of chickens. Animal Biotechnology (Poultry and Fish) 1: 7-13.Google Scholar
EZE, C.D., OKWOR, C.E., OKOYE, J.O.A., ONAH, D.N. and SHOYINKA, S.V.O. (2012) Effects of Moringa oleifera methanolic leaf extract on the morbidity and mortality of chickens experimentally infected with Newcastle disease virus (Kudu 113) strain. Journal of Medicinal Plants Research 6 (27): 1-7.Google Scholar
EZE, I.A. and IKE, A.C. (2015) The serological status for Newcastle disease in local chickens of live bird markets and households in Nsukka, Enugu state, Nigeria. Nigerian Journal of Microbiology 29: 3096-3104.Google Scholar
FAO (2006) Statistics division. Datos agrı´colas de FAOSTAT. http://faostat.fao.org.Google Scholar
FAYED, R.H., RAZEK, A.H.A. and JEHAN, M.O. (2011) Effect of dietary garlic supplementation on performance, carcass traits, and meat quality in broiler chickens. Proceedings of the XVth International Congress of the International Society for Animal Hygiene, Vienna, Austria, pp. 471-474.Google Scholar
FOREMAN, P.M., FRIEDMAN, G.K., CASSADY, K.A. and MARKERT, J.M. (2017) Oncolytic viriotherapy for the treatment of malignant glioma. Neurotherapeutics 14 (2): 333-344.Google Scholar
FULLER, R. (1989) Probiotics in man and animals. Journal of Applied Bacteriology 66: 365-378.Google Scholar
GALDON, R.B., RODRIGUEZ, T.C., RODRIGUEZ, R.M.E. and ROMERO, D.C. (2008) Fructans and major compounds in onion cultivars (Allium cepa). Journal of Food Composite Analysis 22: 25-32.Google Scholar
GARCIA, S.C., LOPEZ, R.N., MORALES, R., OLVERA, M.A., MARQUEZ, M.A., MERINO, R., MILLER, P.J. and AFONSO, C.L. (2013) Molecular epidemiology of Newcastle disease in Mexico and the potential spillover of viruses from poultry into wild bird species. Applied and Environmental Microbiology 79 (16): 4985-4992.Google Scholar
GBENDA, O.E., ADEBISI, O.E., FAJEMISIN, A.N. and ADETUNJI, A.V. (2009) Response of broiler chickens in terms of performance and meat quality to Garlic (Allium sativum) supplementation. African Journal of Agricultural Research 4 (5): 511-517.Google Scholar
GOODARZI, M., LANDY, N. and NANEKRANI, S. (2013) Effect of onion (Allium cepa L.) as an antibiotic growth promoter substitution on performance, immune responses and serum biochemical parameters in broiler chicks. Health 5 (8): 1210-1215.Google Scholar
HARTWELL, H.L. (1974) Saccharomyces cerevisiae cell cycle. Bacteriological Reviews 38 (2): 164-198.Google Scholar
HASSAN, E.R., ELBAYOUMI, K.M., MEKKY, H.M., SEDEEK, D., RABIE, N.S. and GIRH, Z.M.S.A. (2013) Comparative study on effect of garlic extract and probiotics on the productivity and immune response of broiler chickens to live Newcastle disease vaccine. Global Veterinaria 11 (5): 630-633.Google Scholar
ICIEK, M., KWIECIEŃ, I. and WŁODEK, L. (2009) Biological Properties Of Garlic And Garlic-Derived Organosulfur Compounds. Environmental and Molecular Mutagenesis 50 (3): 247-265.Google Scholar
JAFARI, R.A., JALAI, M.R., GHORBANPOOR, M. and SARAEI, S.M. (2008) Effect of dietary garlic on immune response of broiler chicks to live Newcastle disease vaccine. Pakistan Journal of Biological Science 11 (14): 1848-1851.Google Scholar
JAIME, L., MARTÍN-CABREJAS, M.A., MOLLÁ, E., LÓPEZ-ANDRÉU, F.J. and ESTEBAN, R.M. (2001) Effect of storage on fructan and fructooligosaccharide of onion (Allium cepa L.). Journal of Agricultural and Food Chemistry 49: 982-988.Google Scholar
KHAN, R.U., CHAND, N. and ALI, A. (2016a) Effect of organic acids on the performance of Japanese quails. Pakistan Journal of Zoology 48: 1799-1803.Google Scholar
KHAN, R.U., NAZ, S., DHAMA, K., KATHRIK, K., TIWARI, R., ABDELRAHMAN, M.M., ALHIDARY, I.A. and ZAHOOR, A. (2016b) Direct-fed microbial: beneficial applications, modes of action and prospects as a safe tool for enhancing ruminant production and safeguarding health. International Journal of Pharmacology 12 (3): 220-231.Google Scholar
KIRIL, M., CLAUDIO, L. and PATTI, J. (2016) Newcastle disease - a solved problem or a continuous challenge? Veterinary Microbiology 1135 (16): 30804-30805.Google Scholar
KOTOWSKA, M., ALBRECHT, P. and SZAJEWSKA, H. (2005) Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomised double-blind placebo-controlled trial. Alimentary Pharmacology Therapeutics 21: 583-590.Google Scholar
LEE, U.S., LEE, H.J., CHOI, H.S., LEE, S.J., OHNISI-KAMEYAMA, M., KOZUKUE, N., LEVIN, E.C. and FRIEDMAN, M. (2008) Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products. Journal of Agriculture and Food Chemistry 56: 8541-8548.Google Scholar
LILLY, D.M. and STILLWELL, R.H. (1965) Probiotics: growth promoting factors produced by microorganisms. Science 147: 747-748.Google Scholar
LIU, J.J., KONG, I.I., ZHANG, G.C., JAYAKODY, L.N., KIM, H., XIA, P.F., KWAK, S., SUNG, B.H., SOHN, J.H., WALUKIEWICZ, H.E., RAO, C.V. and JIN, Y.S. (2016) Metabolic engineering of probiotic Saccharomyces boulardii. Applied and Environmental Microbiology 82: 2280-2287.Google Scholar
LIU, X.F., WAN, H.Q., NI, X.X., WU, Y.T. and LIU, W.B. (2003) Pathotypical and genetypical characterisation of strains of Newcastle disease virus isolated from outbreaks in chicken and goose flocks in some regions of China 1985 - 2001. Archives of Virology 148: 1387-403.Google Scholar
LUKANOV, H., GENCHEV, A. and RIBARSKI, S. (2015) Effect of feed supplementation with garlic power on meat productivity and meat quality traits of classic Ross 308 male hybrid chickens. Trakia Journal of Sciences 1: 66-67.Google Scholar
MANAFI, M., HEDAYATI, M. and MIRZAIE, S. (2018) Probiotic Bacillus species and Saccharomyces boulardii improve performance, gut histology and immunity in broiler chickens. South African Journal of Animal Science 42 (2): 379-389.Google Scholar
MILLER, P.J., KOCH, G., SUAREZ, D. and et al. (2013) Newcastle disease, other paramyxoviruses, and avian metapneumovirus infections, in: SWAYNE, D.E., GLISSON, J.R., MCDOUGALD, L.R., NOLAN, L.K., SUAREZ, D.L. & NAIR, V. (Eds) Diseases of Poultry, 13th ed., pp. 250-377 (Ames IA: Blackwell Publishing).Google Scholar
MOHAMMED, A.A., JACOBS, J.A., MURUGESAN, G.R. and CHENG, H.W. (2018) Effect of dietary symbiotic supplement on behavioral patterns and growth performance of broiler chickens reared under heat stress. Poultry Science 97 (4): 1101-1108.Google Scholar
NAVIDSHAD, B., DARABIGHENE, B. and MALECKY, M. (2016) Garlic: An Alternative to Antibiotics in Poultry Production, A Review. Iranian Journal of Applied Animal Science 8 (1): 9-17.Google Scholar
OFFICE INTERNATIONAL DES EPIZOOTIES (OIE) (2013) Newcastle disease, in: Aetiology Epidemiology Diagnosis Prevention and Control References. http://www.oie.int/fileadmin/Home/eng/Animal_Health_in_the_World/docs/pdf/Disease_cards/NEWCASTLE_DISEASE.pdf.Google Scholar
OLIVEIRA, M.C., FIGUEIREDO-LIMA, D.F., FILHO, D.E.F., MARQUES, R.H. and MORAES, V.M.B. (2009) Effect of mannanoligosaccharides and/or enzymes on antibody titers against infectious bursal and Newcastle disease viruses. Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 61 (1): http://dx.doi.org/10.1590/S0102-09352009000100002.Google Scholar
POURALI, M., MIRGHELENJ, S. and KERMANSHAHI, H. (2010) Effects of garlic powder on productive performance and immune response of broiler chickens challenged with Newcastle disease virus. Global Veterinaria 4 (6): 612-616.Google Scholar
RAHMAN, S., KHAN, S., CHAND, N., SADIQUE, U. and KHAN, U.R. (2017) In vivo effects of Allium cepa L. on the selected gut microflora and intestinal histomorphology in broiler. Acta Histochemica 119 (5): 446-450.Google Scholar
RAJPUT, I.R., LI, L.Y., XIN, X., WU, B.B., JUAN, Z.L., CUI, Z.W., YU, D.Y. and LI, W.F. (2013a) Effect of Saccharomyces boulardii and Bacillus subtilis B10 on intestinal ultrastructure modulation and mucosal immunity development mechanism in broiler chickens. Poultry Science 92: 956-965.Google Scholar
RAJPUT, I.R., LI, Y.L., XU, X., HUANG, Y., ZHI, W.C., YU, D.Y. and LI, W. (2013b) Supplementary effect of Saccharomyces boulardii and Bacillus subtilits B10 on digestive enzyme activities, antioxidation capacity and blood homeostasis in broiler. International Journal of Agriculture and Biology 15: 231-237.Google Scholar
RIVLIN, R. (2001) Historical perspective on the use of garlic. The Journal of Nutrition 131: S1-S4.Google Scholar
ROBERFROID, M. (2007) Prebiotics: The concept revisited. The Journal of Nutrition 137 (2): S830-S837.Google Scholar
ROLDÁN-MARÍN, E., SÁNCHEZ-MORENO, C., LLORÍA, R., ANCOS, B. and CANO, M.P. (2009) Onion high-pressure processing: Flavonol content and antioxidant activity. Food Science and Technology 42 (4): 835-841.Google Scholar
SAFDAR, K., MUHAMMAD, K. and NAZ, R. (2016) Effect of herbal extracts on serum minerals, lipid profile and anti-NDV-HI antibody levels of vaccinated broiler chicks. Pakistan Journal of Zoology 48 (6): 1715-1719.Google Scholar
SALEH, A.A., EBEID, T.A. and ABUDABOS, A.M. (2018) Effect of dietary phytogenics (herbal mixture) supplementation on growth performance, nutrient utilisation, antioxidative properties, and immune response in broilers. Environmental Science and Pollution Research 25 (15): 14606-14613, doi.org/10.1007/s11356-018-1685-z.Google Scholar
SALMINEN, S. (1996) Uniqueness of probiotic strains. IDF Nutrition Newsletter 5: 16-18.Google Scholar
SHALINI, R., ABINAYA, G., SARANYA, P. and ANTONY, U. (2017) Growth of selected Probiotic bacterial strains with fructans from Nendran banana and garlic. Food Science and Technology 83: 68-78.Google Scholar
SHIRISHA, R., KRISHNADAIDA RAJU, M.V.L.N., REDDY, S.S. and REDDY, V.R. (2017) Effect of dietary supplementation of probiotic (problend) on immune status, biochemical profile and E. coli counts in commercial broiler chicken. Journal of Animal Research 7 (4): 717-721.Google Scholar
SIMON, O. (2005) Micro-organisms as feed additives-probiotics. Advances in Pork Production 39: 161-167.Google Scholar
SPRADBROW, P.B. (1994) Newcastle disease in village chickens. Poultry Science Review 5: 57-96.Google Scholar
SUSTA, L., HAMAL, K.R., MILLER, P.J., CARDENAS-GARCIA, S., BROWN, C.C., PEDERSEN, J.C., GONGORA, V. and AFONSO, C.L. (2014) Separate evolution of virulent Newcastle disease viruses from Mexico and Central America. Journal of Clinical Microbiology 52 (5): 1382-1390.Google Scholar
TALEBI, A., AMANI, A., POURMAHMOD, M., SAGHAEI, P. and REZAIE, R. (2015) Symbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens. Veterinary Research Forum 6 (3): 191-197.Google Scholar
THORNTON, P.K. (2010) Livestock production: recent trends, future prospects. Philosophical Transactions of the Royal Society of London. Series B. Biological Science 365: 2853-2867.Google Scholar
USDA (2014) Basic Report 02020, Spices, garlic powder. National Nutrient Database for Standard Reference Release 27, Report Date: September 29, 2014 22:01 EDT.Google Scholar
WAHEED, S., HASNAIN, A., AHMAD, A., TARAR, O.M., YAQEEN, Z. and ALI, M. (2017) Effect of spices and sweet violet extracts to replace antibiotics and antioxidants in feed on broiler performance, hematology, lipid profile and immunity. The Journal of Animal and Plant Sciences 27 (3): 714-724.Google Scholar