Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-23T14:02:18.147Z Has data issue: false hasContentIssue false

Heracleum persicum: chemical composition, biological activities and potential uses in poultry nutrition

Published online by Cambridge University Press:  29 April 2019

L. CHANGXING
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
D. DONGFANG
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
Z. LIXUE
Affiliation:
Department of Physiology, Medical College of Northwest Minzu University, 730000 Lanzhou, Gansu, China
M. SAEED
Affiliation:
Department of Animal Nutrition, Cholistan University of Veterinary and Animal Sciences, Bahawalpur 63100, Pakistan
M. ALAGAWANY*
Affiliation:
Poultry Department, Faculty of Agriculture, Zagazig University, 44511 Zagazig, Egypt
M.R. FARAG
Affiliation:
Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt
M. CHENLING*
Affiliation:
Department of Respiratory, Fourth People's Hospital of Qinghai Province, 810000 Xining, China
L. JIANHUA*
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
Get access

Abstract

Heracleum persicum (golpar) is an endemic medicinal plant that is commonly known as hogweed or Persian hogweed. It contains flavonoids and furanocoumarins that probably could stimulate both cell- and antibody-mediated immune responses. Besides, golpar has a substantial immunostimulatory effect on beta-lymphocytes and macrophages that played important role in antibody synthesis. Its extract at a supplementation level of 1-2.5 ml/l in drinking water showed a remarkable increase in the total immunoglobulins (Ig) (70%), immunoglobulin G (IgG) (100%) and immunoglobulin M (IgM) (94%) titres and an increase in antibody titre against Newcastle disease virus (96%) in broilers. In addition, supplementation positively affected the feed intake (9.4%), weight gain (14.7%) and food conversion ratio (FCR) (8.7%) in broilers. Moreover, in several studies, it has potential as an antifungal, antidiabetic, hypocholesterolaemic and growth enhancer agent; which endorsed its extensive contents of phytochemicals (terpenoids, triterpenes, furanocoumarins, volatile substances, flavonoids and alkaloids). It has a positive effect on the levels of glutathione (GSH), peroxidation lipids (MDA), the total antioxidant capacity of plasma or ferric reducing ability of plasma (FRAP) and glutathione s-transferase (GST), in addition to modulatory effects on liver enzymes including alanine transferase (ALT) and aspartate transferase (AST). After reviewing the published literature, it was apparent that golpar has multidimensional biological effects. Nevertheless, little research is available on the effects of golpar on productive performance and other health-related parameters in avian species. Hence, this review encourages veterinarians and poultry researcher to undertake further work to demonstrate the promising beneficial effects of golpar at effective levels to potentially replace the synthetic antibiotic growth promoters in commercial poultry diets.

Type
Review
Copyright
Copyright © World's Poultry Science Association 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ABOU-ELKHAIR, R., AHMED, H. and SELIM, S. (2014) Effects of black pepper (piper nigrum), turmeric powder (curcuma longa) and coriander seeds (coriandrum sativum) and their combinations as feed additives on growth performance, carcass traits, some blood parameters and humoral immune response of broiler chickens. Asian-Australasian Journal of Animal Sciences 27: 847.Google Scholar
AFRISHAM, R., ABEROMAND, M., GHAFFARI, M.A., SIAHPOOSH, A. and JAMALAN, M. (2015) Inhibitory effect of heracleum persicum and ziziphus jujuba on activity of alpha-amylase. Journal of Botany,2015: Article ID 824683, 8 pages, https://doi.org/10.1155/2015/824683.Google Scholar
AMIN, G. (1991) Iranian traditional medicinal plants. Research Deputy of Health Ministry, Tehran: 130.Google Scholar
AMIZADEH, M., HEJAZI, M.J. and SARYAZDI, G.A. (2013) Fumigant toxicity of some essential oils on tetranychus urticae (acari: Tetranychidae). International Journal of Acarology 39: 285-289.Google Scholar
ARAIN, M.A., MEI, Z., HASSAN, F.U., SAEED, M., ALAGAWANY, M., SHAR, A.H. and RAJPUT, I.R. (2018a) Lycopene: a natural antioxidant for prevention of heat-induced oxidative stress in poultry. World's Poultry Science Journal74: 89-100.Google Scholar
ARAIN, M.A., SAEED, M., HASSAN, F.U., RASHID, I., ZOHAIB, R., BHUTTO, A., ALAGAWANY, M. and SHAR, A.H. (2018b) Health benefits and potential applications of anthocyanins in poultry feed industry. World's Poultry Science Journal 74: 251-264.Google Scholar
ARUOMA, O.I. (2003) Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 523: 9-20.Google Scholar
ASGARPANAH, J., MEHRABANI, G.D., AHMADI, M., RANJBAR, R. and ARDEBILY, M.S.-A. (2012) Chemistry, pharmacology and medicinal properties of heracleum persicum desf. Ex fischer: A review. Journal of Medicinal Plants Research 6: 1813-1820.Google Scholar
AYNEHCHI, Y., ALIABADI, Z. and SURMAGHI, M.H. (1978) Fouranocumarins in roots of Heracleum persicum. Acta Horticultrae 73: 103-107.Google Scholar
BAFNA, A. and MISHRA, S. (2009) Antioxidant and immunomodulatory activity of the alkaloidal fraction of cissampelos pareira linn. Scientia pharmaceutica 78: 21-32.Google Scholar
BRUNTON, L.L., LAZO, J.S. and PARKER, K.L. (2006) Goodman & gilman's the pharmacological basis of therapeutics. Mcgraw-hill companies. New York, NY.Google Scholar
CHO, J.Y., PARK, S.C., KIM, T.W., KIM, K.S., SONG, J.C., LEE, H.M., SUNG, H.J., RHEE, M.H., KIM, S.K. and PARK, H.J. (2006) Radical scavenging and anti-inflammatory activity of extracts from opuntia humifusa raf. Journal of Pharmacy & Pharmacology 58: 113.Google Scholar
CHRISTAKI, E., BONOS, E., GIANNENAS, I. and FLOROU-PANERI, P. (2012) Aromatic plants as a source of bioactive compounds. Agriculture 2: 228-243.Google Scholar
CORUH, N., SAGDICOGLU CELEP, A.G. and OZGOKCE, F. (2007) Antioxidant properties of prangos ferulacea (l.) lindl., chaerophyllum macropodum boiss. And heracleum persicum desf. From apiaceae family used as food in eastern anatolia and their inhibitory effects on glutathione-s-transferase. Food Chemistry 100: 1237-1242.Google Scholar
DHAMA, K., KARTHIK, K., KHANDIA, R., MUNJAL, A., TIWARI, R., RANA, R., KHURANA, S.K., ULLAH, S., KHAN, R.U., ALAGAWANY, M., FARAG, M.R., DADAR, M. and JOSHI, S.K. (2018) Medicinal and therapeutic potential of herbs and plant metabolites / extracts countering viral pathogens - current knowledge and future prospects. Current Drug Metabolism 19: 236-263.Google Scholar
DHAMA, K., SAMINATHAN, M., JACOB, S.S., SINGH, M., KARTHIK, K., AMARPAL, , TIWARI, R., SUNKARA, L.T., MALIK, Y.S. and SINGH, R.K. (2015) Effect of immunomodulation and immunomodulatory agents on health with some bioactive principles, modes of action and potent biomedical applications. International Journal of Pharmacology 11: 253-290.Google Scholar
FARAG, M.R. and ALAGAWANY, M. (2019) The role of Astragalus membranaceus as immunomodulator in poultry. World's Poultry Science Journal 75: 43-54, doi.org/10.1017/S0043933918000739.Google Scholar
FRANCIOSINI, M.P., CASAGRANDE-PROIETTI, P., FORTE, C., BEGHELLI, D., ACUTI, G., ZANICHELLI, D., DAL BOSCO, A., CASTELLINI, C. and TRABALZA-MARINUCCI, M. (2016) Effects of oregano (Origanum vulgare l.) and rosemary (rosmarinus officinalis l.) aqueous extracts on broiler performance, immune function and intestinal microbial population. Journal of Applied Animal Research 44: 474-479.Google Scholar
GEETHA, V. and CHAKRAVARTHULA, S.N. (2018) Chemical composition and anti-inflammatory activity of Boswellia ovalifoliolata essential oils from leaf and bark. Journal of Forestry Research 29: 373-381.Google Scholar
GHASEMI, H.A., KASANI, N. and TAHERPOUR, K. (2014) Effects of black cumin seed (Nigella sativa l.), a probiotic, a prebiotic and a synbiotic on growth performance, immune response and blood characteristics of male broilers. Livestock Science 164: 128-134.Google Scholar
HAJHASHEMI, V., SAJJADI, S.E. and HESHMATI, M. (2009) Anti-inflammatory and analgesic properties of heracleum persicum essential oil and hydroalcoholic extract in animal models. Journal of Ethnopharmacology 124: 475-480.Google Scholar
HEMATI, A., AZARNIA, M. and ANGAJI, S.A. (2010) Medicinal effects of heracleum persicum (golpar). Middle East Journal of Scientific Research 5 (3): 174-176.Google Scholar
JADHAV, K., SHARMA, K., KATOCH, S., SHARMA, V. and MANE, B. (2015) Probiotics in broiler poultry feeds: A review. Journal of Animal Nutrition and Physiology 1: 04-16.Google Scholar
JAMSHIDPARVAR, A., JAVANDEL, F., SEIDAVI, A., BLANCO, F.P., MARÍN, A.L.M., RAMÍREZ, C.A., BUENDÍA, E.A. and NÚÑEZ-SÁNCHEZ, N. (2017) Effects of golpar ( heracleum persicum desf.) and probiotics in drinking water on performance, carcass characteristics, organ weights, blood plasma constituents, and immunity of broilers. Environmental Science & Pollution Research 24: 23571.Google Scholar
JAYAPRAKASHA, G., OHNISHI-KAMEYAMA, M., ONO, H., YOSHIDA, M. and JAGANMOHAN RAO, L. (2006) Phenolic constituents in the fruits of cinnamomum zeylanicum and their antioxidant activity. Journal of Agricultural and Food Chemistry 54: 1672-1679.Google Scholar
KAWAKITA, S., GIEDLIN, H. and NOMOTO, K. (2005) Immunomodulators from higher plants. Journal of Natural Medicines 46: 34-38.Google Scholar
KHEIRI, F., RAHIMIAN, Y. and RAFIEE, A. (2014) Effect of Heracleum persicum extract on performance and some haematological parameters in broiler chicks. Research Opinions in Animal & Veterinary Sciences 4: 522-525.Google Scholar
KHOSRAVI, R.A., SHOKRI, H., FARAHNEJAT, Z., CHALANGARI, R. and KATALIN, M. (2013) Antimycotic efficacy of Iranian medicinal plants towards dermatophytes obtained from patients with dermatophytosis. Chinese Journal of Natural Medicines 11: 43-48.Google Scholar
KOUSHA, A. and BAYAT, M. (2012) Bactericidal and fungicidal activity of methanolic extracts of heracleum persicum desf. Ex fischer against some aquatic and terrestrial animal pathogens. International Journal of Pharmacology 8: 652-656.Google Scholar
LEE, K.W., KIM, J.S. and OH, S.T. (2015) Effects of dietary sanguinarine on growth performance, relative organ weight, cecal microflora, serum cholesterol level and meat quality in broiler chickens. Journal of Poultry Science 52: 15-22.Google Scholar
LUNDBERG, I.E. (2003) Clinical symptoms in patients with myositis–an acquired metabolic myopathy? Current opinion in rheumatology 15: 675-678.Google Scholar
MACHIN, M., SIMOYI, M.F., BLEMINGS, K.P. and KLANDORF, H. (2004) Increased dietary protein elevates plasma uric acid and is associated with decreased oxidative stress in rapidly-growing broilers. Comparative Biochemistry & Physiology Part B Biochemistry & Molecular Biology 137: 383-390.Google Scholar
MERIJANIAN, A., COLASURDO, T., SAMTAK, P., ULLRICH, J. and SPAGNUOLO, J. (1980) The furanocoumarins of heracleum persicum. L. Revista Latinoamericana De Química 11: 51-53.Google Scholar
MOJAB, F., RUSTAIYAN, A.H. and JASBI, A.R. (2002) Essential oils of heracleum persicum desf.Ex fischer leaves. Daru Journal of Pharmaceutical Sciences 10: 6-8.Google Scholar
NAEINI, A., KHOSRAVI, A., CHITSAZ, M., SHOKRI, H. and KAMLNEJAD, M. (2009) Anti-candida albicans activity of some Iranian plants used in traditional medicine. Journal de Mycologie Médicale 19: 168-172.Google Scholar
NAEINI, A., SHOKRI, H. and KHOSRAVI, A.R. (2013a) Immunostimulatory effects of aqueous extract of heracleum persicum desf. On mouse peritoneal macrophages. Jundishapur Journal of Microbiology 6: 261-266.Google Scholar
NAEINI, A., SHOKRI, H. and KHOSRAVI, A.R. (2013b) Immunostimulatory effects of aqueous extract of heracleum persicum desf. On mouse peritoneal macrophages. Jundishapur Journal of Microbiology 6: 1-6.Google Scholar
NEHRU, P.A., SUNANDHADEVI, S., RAMA, T. and MUNIYAPPAN, N. (2017) Effect of probiotic supplementation on growth performance of crossbred calves in an organized cattle farm. Journal of Animal Health and Production 5 (3): 89-91.Google Scholar
NICKAVAR, B. and ABOLHASANI, F.A.-S. (2009) Screening of antioxidant properties of seven umbelliferae fruits from Iran. Pakistan Journal of Pharmaceutical Sciences 22: 30-35.Google Scholar
NORDBERG, J. and ARNÉR, E.S. (2005) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radical Biology and Medicine 39: 1287.Google Scholar
ORAYAGA, K., OLUREMI, O. and ADENKOLA, A. (2016) Effect of water soaking of sweet orange (citrus sinensis) fruit peels on haematology, carcass yield and internal organs of finisher broiler chickens. Journal of Animal Health and Production 4: 65-71.Google Scholar
OWNAGH, A., FALLAHI, M., RAHMAN, B. and MOHAMMADZADEH, D. (2015) Effect of savory essential oil, garlic powder, and garlic aqueous extract on fungal load of poultry feed. Journal of Mycology Research 2: 23-30.Google Scholar
PANAHI, Y., DADJO, Y., PISHGOO, B., AKBARI, A. and SAHEBKAR, A. (2015) Clinical evaluation of the anti-inflammatory effects of heracleum persicum fruits. Comparative Clinical Pathology 24: 971-974.Google Scholar
PANAHI, Y., PISHGOO, B., BEIRAGHDAR, F., ARAGHI, Z.M., SAHEBKAR, A. and ABOLHASANI, E. (2011) Results of a randomized, open-label, clinical trial investigating the effects of supplementation with heracleum persicum extract as an adjunctive therapy for dyslipidemia. ScientificWorldJournal 11: 592-601.Google Scholar
POURAKBARI, M., SEIDAVI, A., ASADPOUR, L. and MARTÍNEZ, A. (2016) Probiotic level effects on growth performance, carcass traits, blood parameters, cecal microbiota, and immune response of broilers. Anais da Academia Brasileira de Ciências 88: 1011-1021.Google Scholar
RAZZAGHI-ABYANEH, M., SABERI, R., SHARIFAN, A., REZAEE, M.-B., SEIFILI, R., HOSSEINI, S.-I., SHAMS-GHAHFAROKHI, M., NIKKHAH, M., SABERI, I. and AMANI, A. (2013) Effects of heracleum persicum ethyl acetate extract on the growth, hyphal ultrastructure and aflatoxin biosynthesis in aspergillus parasiticus. Mycotoxin Research 29: 261-269.Google Scholar
RHEE, M.H., PARK, H.-J. and CHO, J.Y. (2009) Salicornia herbacea: Botanical, chemical and pharmacological review of halophyte marsh plant. Journal of Medicinal Plants Research 3: 548-555.Google Scholar
SAEED, M., ALAGAWANY, M., FAZLANI, S.A., KALHORO, S.A., NAVEED, M., ALI, N., ARAIN, M.A. and CHAO, S. (2019) Health promoting and pharmaceutical potential of ferulic acid for the poultry industry. World's Poultry Science Journal 75: 83-92, doi.org/10.1017/S0043933918000740.Google Scholar
SAYYAH, M., MOAIED, S. and KAMALINEJAD, M. (2005) Anticonvulsant activity of heracleum persicum seed. Journal of Ethnopharmacology 98: 209-211.Google Scholar
SEAL, B.S., LILLEHOJ, H.S., DONOVAN, D.M. and GAY, C.G. (2013) Alternatives to antibiotics: A symposium on the challenges and solutions for animal production. Animal Health Research Reviews 14: 78-87.Google Scholar
SEFIDKON, F., DABIRI, M. and MOHAMMAD, N. (2004) Analysis of the oil of heracleum persicum l. (seeds and stems). Journal of Essential Oil Research 16: 296-298.Google Scholar
SEFIDKON, F., JALILI, A. and MIRHAJI, T. (2002) Essential oil composition of three artemisia spp. From iran. Flavour and Fragrance Journal 17: 150-152.Google Scholar
SHAHRANI, M., NABAVIZADEH, F., SHIRZAD, H., YOUSEFI, H., MORADI, M.T. and MOGHADDASI, J. (2006) Effect of heracleum persicum extract on acid and pepsin secretion level in both basic and stimulated conditions with pentagastrin in rat. Social Psychiatry & Psychiatric Epidemiology 41: 911-917.Google Scholar
SHAMS-GHAHFAROKHI, M., SHOKOOHAMIRI, M.-R., AMIRRAJAB, N., MOGHADASI, B., GHAJARI, A., ZEINI, F., SADEGHI, G. and RAZZAGHI-ABYANEH, M. (2006) In vitro antifungal activities of allium cepa, allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes. Fitoterapia 77: 321-323.Google Scholar
SHARIFIFAR, F., POURNOURMOHAMMADI, S., ARABNEJAD, M., RASTEGARIANZADEH, R., RANJBARAN, O. and PURHEMMATY, A. (2010) Immunomodulatory activity of aqueous extract of heracleum persicum desf. In mice. Iranian Journal of Pharmaceutical Research 8: 287-292.Google Scholar
SHOKRZADEH, M. and SARAVI, S.S. (2010) The chemistry, pharmacology and clinical properties of sambucus ebulus: A review. Journal of Medicinal Plants Research 4: 095-103.Google Scholar
SOURI, E., FARSAM, H., SARKHEIL, P. and EBADI, F. (2004) Antioxidant activity of some furanocoumarins isolated from heracleum persicum. Pharmaceutical Biology 42: 396-399.Google Scholar
TAGHIZABET, N., MANGOLI, E., ANBARI, F., MASOODI, S.A., TALEBI, A.R. and MAZROOEI, M. (2016) The effect of heracleum persicum (golpar) oil and alcoholic extracts on sperm parameters and chromatin quality in mice. International Journal of Reproductive Biomedicine 14: 365.Google Scholar
TOLOUEE, M., ALINEZHAD, S., SABERI, R., ESLAMIFAR, A., ZAD, S.J., JAIMAND, K., TAEB, J., REZAEE, M.-B., KAWACHI, M. and SHAMS-GHAHFAROKHI, M. (2010) Effect of matricaria chamomilla l. Flower essential oil on the growth and ultrastructure of aspergillus niger van tieghem. International Journal of Food Microbiology 139: 127-133.Google Scholar
TOSUN, F., KıZıLAY, Ç.A., EROL, K., KıLıÇ, F.S., KÜRKÇÜOĞLU, M. and BAŞER, K.H.C. (2008) Anticonvulsant activity of furanocoumarins and the essential oil obtained from the fruits of heracleum crenatifolium. Food Chemistry 107: 990-993.Google Scholar
VIMAL, V. and DEVAKI, T. (2004) Linear furanocoumarin protects rat myocardium against lipidperoxidation and membrane damage during experimental myocardial injury. Biomedicine & Pharmacotherapy 58: 393-400.Google Scholar
YANG, L.-L., LIANG, Y.-C., CHANG, C.-W., LEE, W.-S., KUO, C.-T., WANG, C.-C., LEE, H.-M. and LIN, C.-H. (2002) Effects of sphondin, isolated from heracleum laciniatum, on il–1β-induced cyclooxygenase-2 expression in human pulmonary epithelial cells. Life Sciences 72: 199-213.Google Scholar
ZENG, Z., ZHANG, S., WANG, H. and PIAO, X. (2015) Essential oil and aromatic plants as feed additives in non-ruminant nutrition: A review. Journal of Animal Science and Biotechnology 6: 7.Google Scholar