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Efficacy of dietary vitamin D and its metabolites in poultry - review and implications of the recent studies

Published online by Cambridge University Press:  03 January 2017

S. ŚWIĄTKIEWICZ*
Affiliation:
National Research Institute of Animal Production, Department of Animal Nutrition
A. ARCZEWSKA-WŁOSEK
Affiliation:
National Research Institute of Animal Production, Department of Animal Nutrition
D. BEDERSKA-LOJEWSKA
Affiliation:
National Research Institute of Animal Production, Department of Animal Nutrition
D. JÓZEFIAK
Affiliation:
Poznań University of Life Sciences, Department of Animal Nutrition and Feed Management ul. Wołyńska 33, 60-637 Poznań, Poland
*
Corresponding author: [email protected]
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Abstract

Vitamin D plays many important functions in the animal, as it is necessary for proper calcium (Ca) absorption and use in different biological processes. The aim of several recent experiments with poultry was to evaluate the efficacy of different forms and levels of vitamin D3 in the diets for broiler chickens and laying hens. The results of these studies are presented and discussed in this review paper. Based on these results, the modern high-performing poultry requirement for supplemental vitamin D to maximise mineral digestibility, performance and immunity indices, bone health, and eggshell quality is about 3,000 IU/kg, i.e. much higher than NRC (1994) recommendations. The results of several recent poultry studies have shown that 25-hydroxycholecalciferol (25-OH-D3) is more efficient in commercial poultry nutrition than the basic form of vitamin D3 (cholecalciferol).

Type
Reviews
Copyright
Copyright © World's Poultry Science Association 2017 

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References

ATENCIO, A., EDWARDS, H.M. and PESTI, G.M. (2005a) Effect of the level of cholecalciferol supplementation of broiler breeder hen diets on the performance and bone abnormalities of the progeny fed diets containing various levels of calcium or 25-cholecalciferol. Poultry Science 84: 1539-1603.Google ScholarPubMed
ATENCIO, A., PESTI, G.M. and EDWARDS, H.M. (2005b) Twenty-five hydroxycholecalciferol as a cholecalciferol substitute in broiler breeder hen diets and its effect on the performance and general health of the progeny. Poultry Science 84: 1277-1285.Google Scholar
ATENCIO, A., EDWARDS, H.M., PESTI, G.M. and WARE, G.O. (2006) The vitamin D3 requirement of broiler breeders. Poultry Science 85: 674-692.CrossRefGoogle ScholarPubMed
BAR, A., RAZAPHKOVSKY, V., VAX, E. and PLAVNIK, I. (2003) Performance and bone development in broiler chickens given 25-hydroxycholecalciferol. British Poultry Science 44: 224-233.CrossRefGoogle ScholarPubMed
BROWNING, L.C. and COWIESON, A.J. (2014) Vitamin D fortification of eggs for human health. Journal of the Science of Food and Agriculture 94: 1389-1396.Google Scholar
BROWNING, L.C. and COWIESON, A.J. (2015) Interactive effects of vitamin D3 and strontium on performance, nutrient retention, and bone mineral composition in laying hens. Journal of the Science of Food and Agriculture 95: 1080-1087.Google Scholar
COLET, S., GARCIA, R.G., ALMEIDA PAZ, I.C.L., CALDARA, F.R., BORILLE, R., ROYER, A.F.B., NAAS, I.A. and SGAVIOLI, S. (2015) Bone characteristics of broilers supplemented with vitamin D. Revista Brasileira de Ciência Avícola 17: 325-332.Google Scholar
DELUCA, H.F. (2004) Overview of general physiologic features and functions of vitamin D. American Journal of Clinical Nutrition 80: 1689-1696.CrossRefGoogle ScholarPubMed
DUARTE, V., MINAFRA, C.S., SANTOS, F.R.D. and PERIM, F.D.S. (2015) Inclusion of canthaxanthin and 25-hydroxycholecalciferol in the diet of broiler breeders on performance and incubation parameters. Ciência Rural 45: 2050-2055.Google Scholar
EBRAHIMI, H., SHARIATMADARI, F. and KARIMI TORSHIZI, M.A. (2016) Dietary supplementation and in ovo injection of 1α-OHD3 in a low-calcium and low-phosphorous diets for broilers. Journal of Applied Animal Research 44: 113-117.CrossRefGoogle Scholar
EDWARDS, H.M., SHIRLEY, R.B., ESCOE, W.B. and PESTI, G.M. (2002) Quantitative evaluation of 1-alpha-hydroxycholecalciferol as a cholecalciferol substitute for broilers. Poultry Science 81: 664-669.Google Scholar
FRITTS, C.A. and WALDROUP, P.W. (2005) Comparison of cholecalciferol and 25-hydroxycholecalciferol in broiler diets designed to minimize phosphorus excretion. The Journal of Applied Poultry Research 14: 156-166.Google Scholar
GARCIA, A.F., MURAKAMI, A.E., DUARTE, C.R.D.A., ROJAS, I., PICOLI, K.P. and PUZOTTI, M. (2013) Use of Vitamin D3 and its metabolites in broiler chicken feed on performance, bone parameters and meat quality. >Asian-Australasian Journal of Animal Sciences 26: 408-415.Google Scholar
GÓMEZ-VERDUZCO, G., MORALES-LÓPEZ, R. and AVILA-GOZÀLEZ, E. (2013) Use of 25-hydroxycholecalciferol in diets of broiler chickens: effects on growth performance, immunity and bone calcification. The Journal of Poultry Science 50: 60-64.CrossRefGoogle Scholar
GREEN, J. and PERSIA, M.E. (2012) The effects of feeding high concentrations of cholecalciferol, phytase, or their combination on broiler chicks fed various concentrations of nonphytate phosphorus. The Journal of Applied Poultry Research 21: 579-587.CrossRefGoogle Scholar
HAN, J.C., CHEN, G., WANG, J., ZHANG, J., QU, H.X., ZHANG, C., YAN, Y. and CHENG, Y.H. (2016) Evaluation of relative bioavailability of 25-hydroxycholecalciferol to cholecalciferol for broiler chickens. Asian-Australasian Journal of Animal Sciences 29: 1145-1151.Google Scholar
HAN, J.C., WANG, Y.L., QU, H.X., LIANG, F., ZHANG, J.L., SHI, C.X., DONG, X.S. and CHENG, Y.H. (2012) One alpha-hydroxycholecalciferol improves growth performance, tibia quality, and meat color of broilers fed calcium-and phosphorus-deficient diets. Asian-Australasian Journal of Animal Sciences 25: 267-271.Google Scholar
HAN, J.C., YANG, X.D., ZHANG, T., LI, H., LI, W.L., ZHANG, Z.Y. and YAO, J.H. (2009) Effects of 1α-hydroxycholecalciferol on growth performance, parameters of tibia and plasma, meat quality, and type IIb sodium phosphate cotransporter gene expression of one-to twenty-one-day-old broilers. Poultry Science 88: 323-329.Google Scholar
HUTTON, K.C., VAUGHN, M.A., LITTA, G., TURNER, B.J. and STARKEY, J.D. (2014) Effect of vitamin D status improvement with 25-hydroxycholecalciferol on skeletal muscle growth characteristics and satellite cell activity in broiler chickens. Journal of Animal Science 92: 3291-3292.Google Scholar
JIANG, S., JIANG, Z., YANG, K., CHEN, F., ZHENG, C. and WANG, L. (2015) Dietary vitamin D3 requirement of Chinese yellow-feathered broilers. Poultry Science 94: 2210-2220.CrossRefGoogle ScholarPubMed
KAPPELI, S., FROHLICH, E., GEBHARDT-HENRICH, S.G., PFULG, A., SCHAUBLIN, H., ZWEIFEL, R., WIEDMER, H. and STOFFEL, M.H. (2011a) Effects of dietary supplementation with synthetic vitamin D3 and 25-hydroxycholecalciferol on blood calcium and phosphate levels and performance in laying hens. Archiv für Geflügelkunde 75: 179-184.Google Scholar
KAPPELI, S., GEBHARDT-HENRICH, S.G., FROHLICH, E., PFULG, A., SCHAUBLIN, H. and STOFFEL, M.H. (2011b) Effects of housing, perches, genetics, and 25-hydroxycholecalciferol on keel bone deformities in laying hens. Poultry Science 90: 1637-1644.CrossRefGoogle ScholarPubMed
KESHAVARZ, K. (2003) A comparison between cholecalciferol and 25-OH-cholecalciferol on performance and eggshell quality of hens fed different levels of calcium and phosphorus. Poultry Science 82: 1415-1422.Google Scholar
KHAN, S.H., SHAHID, R., MIAN, A.A., SARDAR, R. and ANJUM, M.A. (2010) Effect of the level of cholecalciferol supplementation of broiler diets on the performance and tibial dyschondroplasia. Journal of Animal Physiology and Animal Nutrition 94: 584-593.Google Scholar
KORELESKI, J. and SWIATKIEWICZ, S. (2005a) Efficacy of different levels of a cholecalciferol 25-OH-derivative in diets with two limestone forms in laying hen nutrition. Journal of Animal and Feed Sciences 14: 305-315.Google Scholar
KORELESKI, J. and SWIATKIEWICZ, S. (2005b) Efficacy of different limestone particle size and 25-hydroxycholecalciferol in broiler diets. Journal of Animal and Feed Sciences 14: 705-714.Google Scholar
LEDWABA, M.F. and ROBERSON, K.D. (2003) Effectiveness of twenty-five-hydroxycholecalciferol in the prevention of tibial dyschondroplasia in Ross cockerels depends on dietary calcium level. Poultry science 82: 1769-1777.CrossRefGoogle ScholarPubMed
MABELEBELE, M., NG'AMBI, J.W. and NORRIS, D. (2013) Effect of dietary vitamin D3 supplementation on meat quality of naked neck chickens. African Journal of Biotechnology 12: 3576-3582.Google Scholar
MATTILA, P., ROKKA, T., KONKO, K., VALAJA, J., ROSSOW, L. and RYHANEN, E.L. (2003) Effect of cholecalciferol-enriched hen feed on egg quality. Journal of Agricultural and Food Chemistry 51: 283-287.CrossRefGoogle ScholarPubMed
MATTILA, P., VALAJA, J., ROSSOW, L., VENALANEN, E. and TUPASELA, T. (2004) Effect of vitamin D2- and D3- enriched diets on egg vitamin D content, production, and bird condition during an entire production period. Poultry Science 83: 433-440.CrossRefGoogle ScholarPubMed
MATTILA, P.H., VALKONEN, E. and VALAJA, J. (2011) Effect of different vitamin D supplementations in poultry feed on vitamin D content of eggs and chicken meat. Journal of Agricultural and Food Chemistry 59: 8298-8303.CrossRefGoogle ScholarPubMed
MICHALCZUK, M., PIETRZAK, D., NIEMIEC, J. and MROCZEK, J. (2010) Effectiveness of vitamin D3 and calcidiol (25-OH-D3) application in feeding broiler chickens-production performance and meat quality. Polish Journal of Food and Nutrition Sciences 60: 121-126.Google Scholar
MORRIS, A., SHANMUGASUNDARAM, R., LILBURN, M.S. and SELVARAJ, R.K. (2014) 25-Hydroxycholecalciferol supplementation improves growth performance and decreases inflammation during an experimental lipopolysaccharide injection. Poultry Science 93: 1951-1956.Google Scholar
MORRIS, A., SHANMUGASUNDARAM, R., MCDONALD, J. and SELVARAJ, R.K. (2015) Effect of in vitro and in vivo 25-hydroxyvitamin D treatment on macrophages, T cells, and layer chickens during a coccidia challenge. Journal of Animal Science 93: 2894-2903.CrossRefGoogle ScholarPubMed
NAAS, I.D.A., BARACHO, M.D.S., BUENO, L.G.F., DE MOURA, D.J., VERCELINO, R.D.A. and SALGADO, D.D. (2012) Use of vitamin D to reduce lameness in broilers reared in harsh environments. Revista Brasileira de Ciência Avícola 14: 165-172.Google Scholar
NASCIMENTO DO, G.R., MURAKAMI, A.E., GUERRA, A.Q.F.M., OSPINAS-ROJAS, I.C., FERREIRA, M.F.Z. and FANHANI, J.C. (2014) Effect of different vitamin D sources and calcium levels in the diet of layers in the second laying cycle. Revista Brasileira de Ciência Avícola 16: 37-42.Google Scholar
NRC NATIONAL RESEARCH COUNCIL (1994) Nutrient Requirements of Poultry. 9th revised edition. National Academy Press, Washington, DC.Google Scholar
PENG, H.W., DING, X.M., BAI, S.P., LUO, Y.H., ZHU, Q. and ZHANG, K.Y. (2013) Effects of maternal dietary 25-hydroxycholecalciferol and progeny dietary vitamin premix on progeny performance, immune responses and bone quality of broiler chicks. Journal of Food, Agriculture & Environment 11: 701-706.Google Scholar
PERSIA, M.E., HIGGINS, M., WANG, T., TRAMPLE, D. and BOBECK, E.A. (2013) Effects of long-term supplementation of laying hens with high concentrations of cholecalciferol on performance and egg quality. Poultry Science 92: 2930-2937.Google Scholar
PLAIMAST, H., KIJPARKORN, S. and ITTITANAWONG, P. (2015) Effects of vitamin D3 and calcium on productive performance, egg quality and vitamin D3 content in egg of second production cycle hens. Thai Journal of Veterinary Medicine 45: 189-195.Google Scholar
RAMA RAO, S.R., RAJU, M.V.L.N., PANDA, A.K., SUNDER, G.S. and SHARMA, R.P. (2006) Effect of high concentrations of cholecalciferol on growth, bone mineralization, and mineral retention in broiler chicks fed suboptimal concentrations of calcium and nonphytate phosphorus. The Journal of Applied Poultry Research 15: 493-501.Google Scholar
RAMA RAO, S.V., RAJU, M.V.L.N., PANDA, A.K., SHYAM SUNDER, G. and SHARMA, R.P. (2009) Performance and bone mineralisation in broiler chicks fed on diets with different concentrations of cholecalciferol at a constant ratio of calcium to non-phytate phosphorus. British Poultry Science 50: 528-535.CrossRefGoogle Scholar
REN, Z., JIANG, S., ZENG, Q., DING, X., BAI, S., WANG, J., LUO, Y, SU, Z., XUAN, Y., YAO, B., CISNEROS, F. and ZHANG, K. (2016) Effect of dietary canthaxanthin and 25-hydroxycholecalciferol supplementation on the performance of duck breeders under two different vitamin regimens. Journal of Animal Science and Biotechnology 7: 2.CrossRefGoogle ScholarPubMed
SAHIN, N., BALCI, T.A., KUCUK, O., SMITH, M.O. and SAHIN, K. (2009) Effects of 25-hydroxycholecalciferol and soy isoflavones supplementation on bone mineralisation of quail. British Poultry Science 50: 709-715.CrossRefGoogle Scholar
SALVADOR, D., FARIA, D.E.D., MAZALLI, M.R., ITO, D.T., FARIA FILHO, D.E.D. and ARAÚJO, L.F. (2009) Vitamins D and C for laying hens at the initial phase of egg production. Revista Brasileira de Zootecnia 38: 887-892.Google Scholar
SAUNDERS-BLADES, J.L. and KORVER, D.R. (2014) The effect of maternal vitamin D source on broiler hatching egg quality, hatchability, and progeny bone mineral density and performance. The Journal of Applied Poultry Research 23: 773-783.CrossRefGoogle Scholar
SAUNDERS-BLADES, J.L. and KORVER, D.R. (2015) Effect of hen age and maternal vitamin D source on performance, hatchability, bone mineral density, and progeny in vitro early innate immune function. Poultry Science 94: 1233-1246.Google Scholar
SANTIAGO, M., DAVID, S., ALEXANDRA, N., EDUARDO, A. and JIMMY, Q.G. (2016) Effect of 25-hydroxycholecalciferol (25-OH-D3) on productive performance and bone mineralization in broiler. Open Journal of Animal Sciences 6: 180-184.Google Scholar
SUN, Z.W., YAN, L., ZHAO, J.P., LIN, H. and GUO, Y.M. (2013) Increasing dietary vitamin D3 improves the walking ability and welfare status of broiler chickens reared at high stocking densities. Poultry Science 92: 3071-3079.Google Scholar
TATARA, M.R., KRUPSKI, W., JANKOWSKI, M., ZDUŃCZYK, Z., JANKOWSKI, J. and STUDZIŃSKI, T. (2011) Effects of dietary calcium content and vitamin D source on skeletal properties in growing turkeys. British Poultry Science 52: 718-729.Google Scholar
TORRES, C.A., VIEIRA, S.L., REIS, R.N., FERREIRA, A.K., SILVA, P.X.D. and FURTADO, F.V.F. (2009) Productive performance of broiler breeder hens fed 25-hydroxycholecalciferol. Revista Brasileira de Zootecnia 38: 1286-1290.CrossRefGoogle Scholar
VIGNALE, K., GREENE, E.S., CALDAS, J.V., ENGLAND, J.A., BOONSINCHAI, N., SODSEE, P., POLOCK, E.D., DRIDI, S. and COON, C.N. (2015) 25-hydroxycholecalciferol enhances male broiler breast meat yield through the mTOR pathway. The Journal of Nutrition 145: 855-863.Google Scholar
WHITEHEAD, C.C., MCCORMACK, H.A., MCTEIR, L. and FLEMING, R.H. (2004) High vitamin D3 requirements in broilers for bone quality and prevention of tibial dyschondroplasia and interactions with dietary calcium, available phosphorus and vitamin A. British Poultry Science 45: 425-436.Google Scholar
WIDEMAN, R.F., BLANKENSHIP, J., PEVZNER, I.Y. and TURNER, B.J. (2015) Efficacy of 25-OH vitamin D3 prophylactic administration for reducing lameness in broilers grown on wire flooring. Poultry Science 94: 1821-1827.CrossRefGoogle ScholarPubMed
YAO, L., WANG, T., PERSIA, M., HORST, R. L. and HIGGINS, M. (2013) Effects of vitamin D3-enriched diet on egg yolk vitamin D3 content and yolk quality. Journal of Food Science 78: C178-C183.Google Scholar
YARGER, J.G., SAUNDERS, C.A., MCNAUGHTON, J.L., QUARLES, C.L., HOLLIS, B.W. and GRAY, R. (1995) Comparison of dietary 25-hydroxycholecalciferol and cholecalciferol in broiler chickens. Poultry Science 74: 1159-1167.Google Scholar