Norflurazon [4-chloro-5-(methylamino)-2-(3-(trifluoromethyl)phenyl)-3(2H)-pyridazinone] persistence in five Georgia soils after application to the same plots in 1982 and 1983 was characterized by rapid initial degradation followed by slow loss of the herbicide. The rate of norflurazon loss at each location for each year was not affected by application rate (1.7 or 3.4 kg ai/ha). Relative rates of norflurazon loss were Dothan loamy sand ≥ Greenville sandy clay loam ≥ Rome gravelly clay loam = Appling coarse sanely loam > Bradson clay loam. The rate of dissipation was slower in 1983 than 1982 in the Greenville and Appling soils. Cool and/or dry environmental conditions combined with higher soil organic matter content caused slower herbicide loss. Norflurazon residue 1 yr after treatment in all soils was greater in 1983 than in 1982. Significant injury to grain sorghum [Sorghum bicolor (L.) Moench. ‘BR 64’) was observed in the spring of 1984 at all locations in all plots that were treated with norflurazon for the previous two seasons. The degree of injury corresponded to the concentration of norflurazon detected at that sampling date. Leaching did not appear to be an important method of norflurazon loss.