Weed competition in this experiment had a more marked effect on sorghum [Sorghum bicolor (L.) Moench, var. RS 610] grain yields than did row spacings or sorghum populations. Sorghum grown in 20-inch, as compared to 40-inch, rows had higher grain and stover yields and lower weed yields and 1000-seed weight. Sorghum populations of 42,000 to 50,000 plants per acre produced higher grain and stover yields than populations of 26,000 to 28,000 plants per acre which had greater weed yields, heads per plant, seed weight per head, seed moisture at harvest, and 1000-seed weight. In hand weeded plots, sorghum yields were not affected by row spacing or sorghum population; but as weed competition increased, sorghum yields increased with narrower rows and higher plant populations. Sorghum yields were reduced 4, 12, and 18% by delaying weeding of plots 3, 4, and 5 weeks as compared with 2 weeks after planting. Weeds that did not emerge until 4 weeks after planting did not reduce sorghum yields.