Published online by Cambridge University Press: 12 June 2017
Five 2,5-dimethyl-1-pyrrolidinecarboxanilides were effective inhibitors of the Hill reaction. However, only the cis isomers were active; the trans isomers were totally inactive. Experiments were conducted using 14C-5328 (cis-2,5-dimethyl-1-pyrrolidinecarboxanilide). A correlation existed between resistance of various plants to 5328 and their ability to metabolize it to water soluble metabolites. Velvetleaf (Abutilon theophrasti Medic.) and proso millet (Panicum miliaceum L.) seedlings were very susceptible to 5328 and were unable to metabolize it. Tall morningglory [Ipomoea purpurea (L.) Roth] seedlings were highly tolerant to 5328 and converted it completely to its metabolites. Corn (Zea mays L. ‘DeKalb variety XL-45′) seedlings which were slightly susceptible to 5328 injury were able to metabolize up to 90% of the parent compound. Corn foliage uptake of 14C-5328 applied to the soil surface occurred through the adventitious roots.