Whitebrush (Aloysia lycioides Cham.) near Llano and Marble Falls, Texas was treated at 19 dates with broadcast applications of the potassium salt of 4-amino-3,5,6-trichloropicolinic acid (picloram) as the 2% granules. At Llano, the average percentages of whitebrush plants killed with 1, 2, and 4 lb/A rates of picloram granules at five dates were 18, 52, and 87; however, at three dates, the 3 lb/A treatment killed 98% of the plants. Picloram granules were applied at 15 dates at Marble Falls where 1, 2, 3, and 4 lb/A rates averaged 17, 43, 68, and 79% of the whitebrush plants killed, respectively. Picloram was most toxic when applied during the cooler months, particularly when application was soon followed by rains. Broadcast sprays of the potassium salt of picloram were included at two dates and were more effective than granules. Most individual whitebrush plants were killed by one-third tablespoon of the 10% granule, or by 2 tablespoons of the 2% granule of picloram applied in an area 2 ft in diam at the base of the stem.