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The influence of retinal illuminance on L- and M-cone driven electroretinograms

Published online by Cambridge University Press:  23 February 2011

JAN KREMERS ,
NEIL R.A. PARRY ,
ATHANASIOS PANORGIAS  and
IAN J. MURRAY
JAN KREMERS*
Affiliation:
Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany School of Life Sciences, University of Bradford, Bradford, UK
NEIL R.A. PARRY
Affiliation:
Manchester Academic Health Science Centre, University of Manchester and Vision Science Centre, Manchester Royal Eye Hospital, Manchester, UK
ATHANASIOS PANORGIAS
Affiliation:
Faculty of Life Sciences, University of Manchester, Manchester, UK
IAN J. MURRAY
Affiliation:
Faculty of Life Sciences, University of Manchester, Manchester, UK
*
*Address for correspondence and reprint requests to: Dr. Jan Kremers, Department of Ophthalmology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany. E-mail: [email protected]
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Abstract

The electroretinographic response to L- and M-cone isolating stimuli was measured at different luminance levels to study the effect of retinal illuminance on amplitude and phase, and how this may influence estimates of L:M ratios in the retina. It was found that the amplitude of L- and M-cone driven responses increases differently with increasing retinal illuminance: L-cone responses increase more quickly than those of M-cones. The L:M ratio does not change strongly with retinal illuminance. The phase of both L- and M-cone driven responses advances with increasing retinal illuminance. There is considerable interindividual variability in the phase difference between the two, but generally M-cone driven responses are phase advanced.

Keywords

L:M ratioLuminanceAmplitudePhaseCone isolation
Type
Research Articles
Information
Visual Neuroscience , Volume 28 , Issue 2 , March 2011 , pp. 129 - 135
Copyright
Copyright © Cambridge University Press 2011

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