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Representation of the temporal raphe within the optic tract of the cat

Published online by Cambridge University Press:  02 June 2009

T. Fitzgibbon  and
W. Burke
T. Fitzgibbon
Affiliation:
Physiology Department, University of Sydney, Australia
W. Burke
Affiliation:
Physiology Department, University of Sydney, Australia
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Abstract

The retinal topography of the cat's optic tract was determined by means of injections of the enzyme horseradish peroxidase (HRP) into the tract. This analysis was accomplished by the subtraction of all HRP injection sites not labeling a defined retinal area from those injection sites which resulted in ganglion cell labeling (Venn diagram analysis). Using this method, the following correspondences were demonstrated for the ipsilateral and contralateral projections: superior retina represented in medial optic tract; inferior retina in lateral tract; and area centralis in a dorsocentral location (which was part of a larger area representing the visual streak). The temporal raphe was represented in the ipsilateral tract as a band curving from the area centralis region toward the dorsomedial border of the tract. Contralateral fibers from a region superior to the optic disc were found to be displaced with respect to the general retinal representation in the optic tract and this appeared to be related to retinal development. The ratio of contralateral to ipsilateral fibers was determined and found to be nonuniform within the tract.

Injection of HRP into the optic tract of the cat also allowed the axons from labeled retinal ganglion cells to be traced within the retina and optic disc. Axons from ganglion cells lying temporal to the raphe curve around the area centralis enter the optic disc on the lateral and inferior aspects. Ganglion cells lying nasal to the raphe send their axons more directly to enter the optic disc on its superior aspect. A schema is proposed whereby the retina is mapped onto the optic tract.

Keywords

Optic tractRetinotopicTemporal rapheTopographyOptic disc
Type
Research Article
Information
Visual Neuroscience , Volume 2 , Issue 3 , March 1989 , pp. 255 - 267
Copyright
Copyright © Cambridge University Press 1989

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References

Aebersold, H., Creuizfeldt, O.D., Kühnt, U. & Sanides, D. (1981). Representation of the visual field in the optic tract and optic chiasma of the cat. Experimental Brain Research 42, 127–145.CrossRefGoogle ScholarPubMed
Bishop, P.O., Kozak, W. & Vakkur, G.J. (1962). Some quantitative aspects of the cat's eye: axis and plane of reference, visual field coordinates, and optics. Journal of Physiology 163, 466–504.CrossRefGoogle ScholarPubMed
Bonhoeffer, F. & Huf, J. (1985). Position-dependent properties of retinal axons and their growth cones. Nature 315, 409–410.CrossRefGoogle ScholarPubMed
Brouwer, B. & Zeeman, W.P.C. (1926). The projection of the retina in the primary optic neuron in monkeys. Brain 49, 1–35.CrossRefGoogle Scholar
Bunt, S.M. (1982). Retinotopic and temporal organization of the optic nerve and tracts in the adult goldfish. Journal of Comparative Neurology 206, 209–226.CrossRefGoogle ScholarPubMed
Chalupa, L.M. & Williams, R.W. (1984). Prenatal development and reorganization in the visual system of the cat. In Development of Visual Pathways in Mammals, ed. Stone, J., Dreher, B. & Rapaport, D.H., pp. 89–102. New York: Alan R. Liss, Inc.Google Scholar
Cook, J.E. (1982). Errant optic axons in the normal goldfish retina reach retinotopic tectal sites. Brain Research 250, 154–158.CrossRefGoogle ScholarPubMed
Cooper, M.L. & Pettigrew, J.D. (1979). The decussation of the retinothalamic pathway in the cat, with a note on the major meridians of the cat's eye. Journal of Comparative Neurology 187, 285–312.CrossRefGoogle ScholarPubMed
Dräger, U.C. (1985). Birth dates of retinal ganglion cells giving rise to the crossed and uncrossed optic projections in the mouse. Proceedings of the Royal Society (London) B 224, 57–77.Google Scholar
Easter, S.S., Rusoff, A.C. & Kish, P.E. (1981). The growth and organization of the optic nerve and tract in juvenile and adult goldfish. Journal of Neuroscience 1, 793–811.CrossRefGoogle ScholarPubMed
FitzGibbon, T. (1982). A simple method of obtaining retinal whole-mounts. Vision Research 22, 1221–1223.CrossRefGoogle ScholarPubMed
FitzGibbon, T., Kerr, L. & Burke, W. (1983). Uptake of horseradish peroxidase by axons of passage and its modification by poly-L-ornithine and dimethylsulphoxide. Journal of Neuroscience Methods 7, 73–88.CrossRefGoogle ScholarPubMed
Goldberg, S. & Coulombre, A.J. (1972). Topographical development of the ganglion cell fiber layer in the chick retina. A whole mount study. Journal of Comparative Neurology 146, 507–518.CrossRefGoogle ScholarPubMed
Graybiel, A.M. (1977). Direct and indirect preoculomotor pathways of the brainstem: an autoradiographic study of the pontine retic-ular formation in the cat. Journal of Comparative Neurology 175, 37–78.CrossRefGoogle ScholarPubMed
Guillery, R.W., Polley, E.H. & Torrealba, F. (1982). The arrangement of axons according to fiber diameter in the optic tract of the cat. Journal of Neuroscience 2, 714–721.CrossRefGoogle ScholarPubMed
Hanker, J.S., Yates, P.E., Metz, C.B. & Rustioni, A. (1977). A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase. Histochemical Journal 9, 789–792.CrossRefGoogle ScholarPubMed
Horton, J.C., Greenwood, M.M. & Hubel, D.H. (1979). Non-retino-topic arrangement of fibres in cat optic nerve. Nature 282, 720–722.CrossRefGoogle ScholarPubMed
Hoyt, W.F. & Luis, O. (1962). Visual fiber anatomy in the infragenic-ulate pathway of the primate. Archives of Ophthalmology 68, 124–136.Google ScholarPubMed
Hughes, A. (1975). A quantitative analysis of the cat retinal ganglion cell topography. Journal of Comparative Neurology 163, 107–128.CrossRefGoogle ScholarPubMed
Illing, R.-B. & Wässle, H. (1979). Visualization of the HRP reaction product using the polarization microscope. Neuroscience Letters 13, 7–11.CrossRefGoogle ScholarPubMed
Kliot, M. & Shatz, C.J. (1982). Genesis of different retinal ganglion cell types in the cat. Society for Neuroscience Abstracts 8, 815.Google Scholar
Laties, A.M. & Sprague, J.M. (1966). The projection of optic fibers to the visual centers in the cat. Journal of Comparative Neurology 127, 35–70.CrossRefGoogle Scholar
Lipp, H.-P. & Schwegler, H. (1980). Improved transport of horseradish peroxidase after injections with a non-ionic detergent (Nonidet P–40) into mouse cortex and observations on the relationship between spread at the injection site and amount of transported label. Neuroscience Letters 20, 49–54.CrossRefGoogle ScholarPubMed
Mastronarde, D.N. (1984). Organization of the cat's optic tract as assessed by single-axon recordings. Journal of Comparative Neurology 227, 14–22.CrossRefGoogle ScholarPubMed
Mesulam, M.-M., Hegarty, E., Barbas, H., Carson, K.A., Gower, E.C., Knapp, A.G., Moss, M.B. & Mufson, E.J. (1980). Additional factors influencing sensitivity in the tetramethyl benzidine method for horseradish peroxidase neurohistochemistry. Journal of Histochemistry and Cytochemistry 28, 1255–1259.CrossRefGoogle ScholarPubMed
Moon, Edley S. & Graybiel, A.M. (1983). The afferent and efferent connections of the feline nucleus tegmenti pedunculopontinus, pars compacta. Journal of Comparative Neurology 217, 187–215.Google Scholar
Morrell, J.I., Greenberger, L.M. & Pfaff, D.W. (1981). Comparison of horseradish peroxidase visualization methods: quantitative results and further technical specifics. Journal of Histochemistry and Cytochemistry 29, 903–916.CrossRefGoogle ScholarPubMed
Murakami, D., Sesma, M.A. & Rowe, M.H. (1982). Characteristics of nasal and temporal retina in Siamese and normally pigmented cats: ganglion cell composition, axon trajectory, and laterality of projection. Brain, Behavior, and Evolution 21, 67–113.CrossRefGoogle ScholarPubMed
Naito, J. (1986). Course of retinogeniculate projection fibers in the cat optic nerve. Journal of Comparative Neurology 251, 376–387.CrossRefGoogle ScholarPubMed
Ogden, T.E. (1983 a). Nerve fiber layer of the macaque retina: retinotopic organization. Investigative Ophthalmology and Visual Science 24, 85–98.Google ScholarPubMed
Ogden, T.E. (1983 b). Nerve fiber layer of the owl monkey retina: retinotopic organization. Investigative Ophthalmology and Visual Science 24, 265–269.Google ScholarPubMed
Polyak, S.L. (1957). The Vertebrate Visual System. Chicago: University of Chicago Press.Google Scholar
Robinson, S. (1987). Ontogeny of the area centralis in the cat. Journal of Comparative Neurology 255, 50–67.CrossRefGoogle ScholarPubMed
Scalia, F. & Arango, V. (1983). The anti-retinotopic organization of the frog's optic nerve. Brain Research 266, 121–126.CrossRefGoogle ScholarPubMed
Shatz, C.J. & Kliot, M. (1982). Prenatal misrouting of the retinogeniculate pathway in Siamese cats. Nature 300, 525–529.CrossRefGoogle ScholarPubMed
Stone, J. (1966). The naso-temporal division of the cat's retina. Journal of Comparative Neurology 126, 585–600.Google ScholarPubMed
Stone, J. (1978). The number and distribution of ganglion cells in the cat's retina. Journal of Comparative Neurology 180, 753–772.CrossRefGoogle ScholarPubMed
Stone, J. (1981). The Wholemount Handbook. A Guide to the Preparation and Analysis of Retinal Wholemounts. Sydney: Maitland Publications.Google Scholar
Stone, J. & Hansen, S.M. (1966). The projection of the cat's retina on the lateral geniculate nucleus. Journal of Comparative Neurology 126, 601–624.Google ScholarPubMed
Thor, G. (1983). Some topological considerations of the optic pathway. Journal of Theoretical Biology 101, 129–136.CrossRefGoogle ScholarPubMed
Torrealba, F., Guillery, R.W., Eysel, U., Polley, E.H. & Mason, C.A. (1982). Studies of retinal representations within the cat's optic tract. Journal of Comparative Neurology 211, 377–396.CrossRefGoogle ScholarPubMed
Torrealba, F., Guillery, R.W., Polley, E.H. & Mason, C.A. (1981). A demonstration of several independent, partially overlapping, retinotopic maps in the optic tract of the cat. Brain Research 219, 428–432.CrossRefGoogle ScholarPubMed
Venn, J. (1971). Symbolic Logic. 2nd Edition. New York: Lennox Hill Publishers & Distribution Co. (Burt Franklin).Google Scholar
Voigt, T., Natto, J. & Wässle, H. (1983). Retinotopic scatter of optic tract fibres in the cat. Experimental Brain Research 52, 25–33.CrossRefGoogle ScholarPubMed
Walsh, C. (1986). Age-related fiber order in the ferret's optic nerve and optic chiasm. Journal of Neuroscience 6, 1635–1642.CrossRefGoogle ScholarPubMed
Walsh, C. & Guillery, R.W. (1984). Fibre order in the pathways from the eye to the brain. Trends in Neuroscience 7, 208–211.CrossRefGoogle Scholar
Walsh, C. & Polley, E.H. (1985). The topography of ganglion cell production in the cat's retina. Journal of Neuroscience 5, 741–750.CrossRefGoogle ScholarPubMed
Walsh, C., Polley, E.H., Hickey, T.L. & Guillery, R.W. (1983). Generation of cat retinal ganglion cells in relation to central pathways. Nature, 302, 611–614.CrossRefGoogle ScholarPubMed
Williams, R.W., Bastiani, M.J., Lia, B. & Chalupa, L.M. (1986). Growth cones, dying axons, and developmental fluctuations in the fiber population of the cat's optic nerve. Journal of Comparative Neurology 246, 32–69.CrossRefGoogle ScholarPubMed
Williams, R.W. & Rakic, P. (1985). Dispersion of growing axons within the optic nerve of the embryonic monkey. Proceedings of the National Academy of Sciences of the U.S.A. 82, 3906–3910.CrossRefGoogle ScholarPubMed