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Timing of Twinning, X-Inactivation and Sex Proportion at Birth

Published online by Cambridge University Press:  21 February 2012

Catherine Derom ,
Robert Vlietinck  and
Robert Derom
Catherine Derom
Affiliation:
Department of Human Genetics, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium; Association for Scientific Research in Multiple Births, Ghent, Belgium.
Robert Vlietinck
Affiliation:
Department of Human Genetics, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium; Association for Scientific Research in Multiple Births, Ghent, Belgium.
Robert Derom
Affiliation:
Association for Scientific Research in Multiple Births, Ghent, Belgium.

Abstract

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Twins are not a homogeneous group. According to zygosity and chorionicity essential differences exist. The lower sex proportion at birth is due to the monozygotic twins, especially the monoamnionic variety. X-inactivation patterns in monozygotic twin girls are totally symmetrical in monoamnionic pairs, almost symmetrical in monochorionic diamnionic pairs and can be very asymmetrical in the dichorionic variety.

Type
Articles
Information
Twin Research and Human Genetics , Volume 10 , Supplement S1 , 01 December 2007 , pp. 8 - 10
Copyright
Copyright © Cambridge University Press 2007