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The Danish Twin Registry in the New Millennium

Published online by Cambridge University Press:  21 February 2012

Axel Skytthe ,
Kirsten Kyvik ,
Lise Bathum ,
Niels Holm ,
James W. Vaupel  and
Kaare Christensen
Axel Skytthe*
Affiliation:
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark. [email protected]
Kirsten Kyvik
Affiliation:
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Lise Bathum
Affiliation:
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Niels Holm
Affiliation:
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
James W. Vaupel
Affiliation:
Max Planck Institute for Demographic Research, Rostock, Germany.
Kaare Christensen
Affiliation:
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
*
*Address for correspondence: Axel Skytthe, The Danish Twin Registry, University of Southern Denmark, J B Winløws Vej 9 B, DK-5000 Odense C., Denmark.

Abstract

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The Danish Twin Registry is the oldest national twin register in the world, initiated in 1954, and, by the end of 2005, contained more than 75,000 twin pairs born in the between 1870 and 2004. The Danish Twin Registry is used as a source for studies on the genetic influence on normal variation in clinical parameters associated with the metabolic syndrome and cardiovascular diseases, clinical studies of specific diseases, and aging and age-related health problems. The combination of survey data, clinical data and linkage to national health-related registers enables follow-up studies of both the general twin population and twins from clinical studies. This paper summarizes the newest extension of the register and gives examples of new developments and phenotypes studied.

Type
Articles/Denmark
Information
Twin Research and Human Genetics , Volume 9 , Issue 6 , 01 December 2006 , pp. 763 - 771
Copyright
Copyright © Cambridge University Press 2006