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Association Between Twin Discordance at 6–9 Weeks' of Gestation and Birthweight Complications

Published online by Cambridge University Press:  21 February 2012

Kirsten Palmer ,
Pavitra Delpachitra ,
Joseph Onwude ,
Luk Rombauts ,
Simon Meagher  and
Stephen Tong
Kirsten Palmer*
Affiliation:
Department of Obstetrics & Gynaecology, Monash Medical Centre, Melbourne, Australia. [email protected]
Pavitra Delpachitra
Affiliation:
Department of Obstetrics & Gynaecology, Monash Medical Centre, Melbourne, Australia.
Joseph Onwude
Affiliation:
Springfield Hospital, Chelmsford, United Kingdom.
Luk Rombauts
Affiliation:
Department of Obstetrics & Gynaecology, Monash Medical Centre, Melbourne, Australia; Monash IVF, Melbourne, Australia.
Simon Meagher
Affiliation:
Monash Ultrasound for Women, Melbourne, Australia.
Stephen Tong
Affiliation:
Department of Obstetrics & Gynaecology, Monash Medical Centre, Melbourne, Australia; Monash Ultrasound for Women, Melbourne, Australia.
*
*Address for correspondence: Dr Kirsten Palmer, Department of Obstetrics and Gynaecology, Monash Medical Centre, 246 Clayton Rd, Clayton VIC 3168, Australia.

Abstract

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Twins achieved through in-vitro fertilisation often undergo a viability ultrasound at 6–9 weeks of gestation. The presence of inter-twin crown-rump length discordance at this stage is not an uncommon finding; however the clinical significance of this is unknown. We analyzed 218 dichorionic twin pregnancies, producing two live fetuses > 24 weeks gestation, to determine whether inter-twin discordance (≥ 85th centile) in the mid-first trimester was associated with birthweight discordance (> 20%), or small for gestational age (< 10th centile). The incidence of birthweight discordance and small for gestational age infants were determined, with no increased risk found for the discordant population. This may provide some reassurance to treating clinicians.

Keywords

twinsdiscordancecrown–rump lengthfirst trimesterbirthweight
Type
Articles
Information
Twin Research and Human Genetics , Volume 13 , Issue 4 , 01 August 2010 , pp. 389 - 392
Copyright
Copyright © Cambridge University Press 2010