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Withdrawal of Perphenazine in Chronic Schizophrenia

Published online by Cambridge University Press:  29 January 2018

C. B. Whittaker
Affiliation:
Bellsdyke Hospital, Larbert. (Gartloch Hospital, Glasgow.)
R. M. Hoy
Affiliation:
Bellsdyke Hospital, Larbert

Extract

Although phenothiazine drugs have been employed in the treatment of schizophrenia for approximately ten years, we are still uncertain of the best method of using these agents. Whilst the indications to start phenothiazine medication may readily be agreed, the point at which to terminate such therapy remains debatable. Some psychiatrists stop the drug before the patient is discharged from hospital, some at discharge, some shortly after, but an increasing number recommend the schizophrenic patient never to stop taking his phenothiazine. On the other hand, the national drug bill has reached such proportions that some hospitals are now cutting down the administration of phenothiazines, and continue them only in those patients whose improvement is marked and clearly related to the drug.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1963

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References

Boyd, E. M. (1960). J. Pharm. Exper. Therap., 128, 75.Google Scholar
Brooks, G. W. (1959). Amer. J. Psychiat., 115, 931.CrossRefGoogle Scholar
Diamond, L. S., and Marks, J. B. (1960). J. Nerv. Ment. Dis., 131, 247.CrossRefGoogle Scholar
Good, W. W., Sterling, M., and Holtzmann, W. (1958). Amer. J. Psychiat., 115, 443.CrossRefGoogle Scholar
Judah, L. N., Josephs, Z. M. and Murphree, O. D. (1961). Ibid, 118, 156.Google Scholar
Lucero, R. J., and Meyer, B. T. (1951). J. Clin. Psychol., 7, 250.3.0.CO;2-G>CrossRefGoogle Scholar
Olson, G. W., and Peterson, D. B. (1960). J. Nerv. Ment. Dis., 131, 252.CrossRefGoogle Scholar
Rothstein, C. (1960). New England Med. J., 262, 67.CrossRefGoogle Scholar
Siegel, S. (1956). Non-parametric Statistics for the Behavioural Sciences. New York: McGraw-Hill.Google Scholar
Weatherall, M. (1962). Brit. Med. J., i, 1219.CrossRefGoogle Scholar
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