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Validity of childhood disintegrative psychosis

General findings of a long-term follow-up study

Published online by Cambridge University Press:  02 January 2018

Svend Erik Mouridsen ,
Bente Rich  and
Torben Isager
Svend Erik Mouridsen*
Affiliation:
Department of Child and Adolescent Psychiatry, Bispebjerg Hospital, Copenhagen, Denmark
Bente Rich
Affiliation:
Rehabilitation and Research Center for Torture Victims, Copenhagen, Denmark
Torben Isager
Affiliation:
Department of Child and Adolescent Psychiatry, Glostrup Hospital, Denmark
*
Svend Erik Mouridsen, Department of Child and Adolescent Psychiatry, Bispebjerg Hospital, DK-2400, Copenhagen, Denmark.
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Abstract

Background

Empirical evidence for the validity of the diagnostic label ‘disintegrative psychosis' is sparse. The issue of whether it is a separate form of infantile autism is unresolved.

Method

To investigate the validity of disintegrative psychosis as defined in ICD–9, the natural history of 13 cases were compared with 39 matched cases of infantile autism on various outcome variables. Average follow-up time was 22 (11–33) years.

Results

Statistically significant differences were found between the two groups in terms of number of admissions to non-psychiatric departments, occurrence of comorbid epilepsy social style, and score on the Global Assessment of Functioning scale. In most other areas assessed there was a tendency, although statistically insignificant, towards a better outcome in the infantile autism comparison group.

Conclusions

Our findings provide some support for maintaining a diagnostic category of disintegrative psychosis as distinct from infantile autism.

Type
Papers
Information
The British Journal of Psychiatry , Volume 172 , Issue 3 , March 1998 , pp. 263 - 267
Copyright
Copyright © 1998 The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III). Washington, DC: APA.Google Scholar
American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn revised) (DSM–III–R). Washington, DC: APA.Google Scholar
American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM–IV). Washington. DC: APA.Google Scholar
Burd, L., Fisher, W. & Kerbeshian, J. (1989) Pervasive disintegrative disorder: are Rett syndrome and Heller dementia infantilis subtypes? Developmental Medicine and Child Neurology, 31, 609–616.Google Scholar
Corbett, J., Harris, R., Taylor, E., et al (1977) Progressive disintegrative psychosis of childhood. Journal of Child Psychology and Psychiatry, 18, 211–219.CrossRefGoogle ScholarPubMed
Creak, E. M. (1963) Childhood psychoses: a review of 100 cases. British Journal of Psychiatry, 109, 84–89.CrossRefGoogle ScholarPubMed
Doll, E. A. (1965) The Vineland Social Maturity Scale: Condensed Manual of Directions (revised edn). Minneapolis. MN: American Guidance Service Inc.Google Scholar
Gillberg, C. & Steffenburg, S. (1987) Outcome and prognostic factors in infantile autism and similar conditions: a population study of 46 cases followed through puberty. Journal of Autism and Developmental Disorders, 17, 273–287.Google Scholar
Gillberg, I. C., Gillberg, C. & Ahlsen, G. (1994) Autistic behaviour and attention deficits in tuberous sclerosis. A population based study. Developmental Medicine and Child Neurology, 36, 50–56.CrossRefGoogle ScholarPubMed
Heller, T. (1908) Dementia infantilis. Zeitschriff für die Erforschung und Behandlung des Jugendlichen Schwachsinns, 2, 141–165.Google Scholar
Hill, A. E. & Rosenbloom, L. (1986) Disintegrative psychosis of childhood: teenage follow-up. Developmental Medicine and Child Neurology, 28, 34–40.CrossRefGoogle ScholarPubMed
Kendell, R. E. (1989) Clinical validity Psychological Medicine, 19, 45–55.Google Scholar
Kurita, H. (1988) The concept and nosology of Heller's syndrome: review of articles and report of two cases. Japanese Journal of Psychiatry and Neurology, 42, 785–793.Google Scholar
Kurita, H., Kita, M. & Miyake, Y. (1992) A comparative study of development and symptoms among disintegrative psychosis and infantile autism with and without speech loss. Journal of Autism and Developmental Disorders, 22, 175–188.Google Scholar
Leiter, R. G. (1969) Examiner's manual for the Leiter international performance scale. Chicago, IL: Stoelting.Google Scholar
Malhotra, S. & Singh, S. P. (1993) Disintegrative psychosis of childhood. An appraisal and case study. Acta Paedopsychiatrica, 56, 37–40.Google ScholarPubMed
Mouridsen, S. E., Rich, B. & Isager, T. (1993) Parental age in infantile autism, autistic-like conditions, and borderline childhood psychosis. Journal of Autism and Developmental Disorders, 23, 387–396.CrossRefGoogle ScholarPubMed
Mouridsen, S. E., Rich, B. & Isager, T. (1998) The validity of childhood disintegrative psychosis: a long term follow-up study. Developmental Medicine and Child Neurology, in press.CrossRefGoogle Scholar
Norusis, M. J. (1993) SPSS for Windows. Advanced Statistics. Release 6.0. Chicago, IL: SPSS Inc.Google Scholar
Rivinus, T. M., Jamison, D. L. & Graham, P. J. (1975) Childhood organic neurological disease presenting as psychiatric disorder. Archives of Disease in Childhood, 50, 115–119.Google Scholar
Siegel, J. (1994) Statistix. Version 4.1 User's Manual. Talahassee, FL: Analytical Software.Google Scholar
Volkmar, F. R. (1992) Childhood disintegrative disorder: issues for DSM–IV. Journal of Autism and Developmental Disorders, 22, 625–642.Google Scholar
Volkmar, F. R. & Cohen, D. J. (1989) Disintegrative disorder or ‘late onset’ autism. Journal of Child Psychology and Psychiatry, 130, 717–724.Google Scholar
Volkmar, F. R. & Rutter, M. (1995) Childhood disintegrative disorder: results of the DSM-IV autism field study. Journal of the American Academy of Child and Adolescent Psychiatry, 34, 1092–1095.Google Scholar
Wechsler, D. (1958) The Measurement and Appraisal of Adult Intelligence (4th edn). Baltimore, MD: Williams and Wilkins.Google Scholar
Wing, L. (1983) Social interpersonal needs. In: Autism in Adolescents and Adults (eds Schopler, E. & Mesibov, G. M.) pp. 337–354. New York: Plenum Press.Google Scholar
World Health Organization (1978) International Classification of Diseases. Mental Disorders: Glossary and Guide to their Classification (9th rev). Geneva: WHO.Google Scholar
World Health Organization (1992) ICD-10: The ICD-10 Classification of Mental and Behavioural Disorders – Clinical Descriptions and Diagnostic Guidelines. Geneva: WHO.Google Scholar
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