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The Use of Self-rating Scales in a Single-patient Multiple Cross-over Trial

Published online by Cambridge University Press:  29 January 2018

R. Kellner
Affiliation:
Department of Psychiatry, University of Liverpool
B. F. Sheffield
Affiliation:
Sefton General Hospital, Liverpool

Extract

The value of measuring changes in symptoms in a single patient has been discussed by a number of authors. (1, 3, 4.) The “self-controlled trial” (1) or the “multiple cross-over method”, i.e. the measurement of responses to repeated and systematic changes in treatment, appears to have advantages over the simple cross-over trial, but the method would be extremely time-consuming in group research with psychiatric patients if the ratings had to be carried out by research workers. The use of valid self-rating scales would make the multiple cross-over method feasible in drug trials with groups of psychiatric patients.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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References

1. Hogben, L., and Sim, M. (1953). “The self-controlled and self-recorded clinical trial for low grade morbidity” Brit. J. prev. soc. Med., 7, 163179.Google Scholar
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